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Portrait Prof. Dr. Wolfgang Wiechert

Prof. Dr. Wolfgang Wiechert

Head of Systems Biotechnology (IBG-1)

Since June 2011 Prof. Wiechert is professor for Computational Systems Biotechnology at the RWTH Aachen and director at IBG-1 (Biotechnology) at the Forschungszentrum Jülich. Here he leads the department of Systems Biotechnology. Born 1960 in Opladen (today Leverkusen) he studied Mathematics and Computer Science at the University of Bonn. 1990 he got his PhD in Theoretical Biology. From 1991 to 1996 he was PostDoc at the former Institute of Biotechnology 2 (Forschungszentrum Jülich). In 1996 he did his habilitation thesis in the field of metabolic flux analysis. From 1996 to 2002 he held a C3-professorship and - due to a call to Tübingen - from 2002 to 2008 a C4-professorship for Simulation and Computer Science in Mechanical Engineering at the University of Siegen. In 2006 he stayed as guest professor at the Institute for Molecular Systems Biology at the ETH Zürich.

His main area of work lies within the field of applied systems bio(techno)logy of microorganisms with a special focus on methodological developments for quantitative biology. Characteristics of his research work are a close integration of experimental and theoretical work within multi disciplinary projects. Prof. Wiechert is developing methods for quantitative metabolomics, fluxomics and proteomics including model based mathematical methods for experimental design, parameter estimation, and process optimization in biotechnological systems. Within the framework of systems biology mathematical models at different levels of details are formulated and used to integrate multi-omics data. These models are then used for process development in industrial biotechnology. Future work will also incorporate micro fluidic methods for single cell analysis. In general all research results are used to drive forward the process of gaining knowledge in the course of an iterative improvement of industrial production systems. This proceeds in close cooperation of all working groups at the IBG-1. Together with industrial partners also diverse examples from industry are investigated and further developed.


Forschungszentrum Jülich GmbH
Institute of Bio- and Geosciences
IBG-1: Biotechnology
52425 Jülich


Phone: +49 2461 61-3118
Fax: +49 2461 61-3870