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Institute of Neuroscience and Medicine

Navigation and service

Dipl.-Phys. David Gräßel

Research fellow

Degree: Diploma in physics

Research Topics:

Polarized Light Imaging (3D-PLI) - High resolution imaging of nerve fiber tracts in the human brain using polarized light
The Connectome project dedicated to reveal the connectivity of interacting brain regions involves different neuroimaging techniques such as optical microscopy and diffusion weighted magnetic resonance imaging. Three-dimensional Polarized Light Imaging (3D-PLI) is an innovative approach to map the spatial orientations of fiber tracts in histological sections of the human brain at a submillimeter scale. The basic principle of 3D-PLI is based on the birefringent properties of the myelin sheaths surrounding nerve axons.
Research Methods:Forschungsschwerpunkt:

Research Methods:

  • 3D-Visualization of neuronal fiber models with Matlab®
  • Hardware programming with LabView®
  • Theory of polarized light propagation in uniaxial birefringent tissue


Institute of Neuroscience and Medicine (INM-1)
Forschungszentrum Jülich
52425 Jülich


Phone: +49 2461 61-4774
Fax: +49 2461 61-3483