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Institute of Neuroscience and Medicine

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Martin Schober

Scientist

Degree: M.Sc. in Technomathematics

Fields of Reserach:

3D Polarized Light Imaging (3D-PLI) is a neuroimaging technique that reconstructs the three-dimensional pathways of nerve fibers in postmortem brains with a resolution at the micrometer scale: By transmitting polarized light through histological brain sections in a polarimeter, the birefringence of the nerve fibers is measured and the underlying fiber orientations are determined.
The reconstruction of the nerve fiber orientations is based on a macroscopic model of uniaxial birefringence which has not been investigated before. In order to better understand the physical mechanisms and processes in 3D-PLI and to verify the use of the macroscopic model, different analytical methods and numerical simulations are developed.


Methodologies:

  • Linear and nonlinear image registration
  • Segmentation
  • Object detection and recognition
  • Parallel processing of large data volumes

Address

Institute of Neuroscience and Medicine (INM-1)
Forschungszentrum Jülich
52425 Jülich

Contact

Phone: +49 2461 61-9148
email: m.schober@fz-juelich.de

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