Degree: M.Sc. in Technomathematics
Fields of Reserach:
3D Polarized Light Imaging (3D-PLI) is a neuroimaging technique that reconstructs the three-dimensional pathways of nerve fibers in postmortem brains with a resolution at the micrometer scale: By transmitting polarized light through histological brain sections in a polarimeter, the birefringence of the nerve fibers is measured and the underlying fiber orientations are determined.
The reconstruction of the nerve fiber orientations is based on a macroscopic model of uniaxial birefringence which has not been investigated before. In order to better understand the physical mechanisms and processes in 3D-PLI and to verify the use of the macroscopic model, different analytical methods and numerical simulations are developed.
- Linear and nonlinear image registration
- Object detection and recognition
- Parallel processing of large data volumes
AddressInstitute of Neuroscience and Medicine (INM-1)