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Supercomputers Shed Light on the Cause of Alzheimer’s

Forschungszentrum Jülich, 23 January 2018 – Deposits from certain protein building blocks – amyloid beta (Aβ) – are viewed as a typical sign of Alzheimer’s disease. How these amyloid plaques are formed exactly has yet to be explained in detail, however. Using computer simulations, Jülich researchers have now been able to demonstrate that the form and distribution of intermediate products in the formation process, known as oligomers, play an important role in the "clumping" of proteins.

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