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PhD student: Novel optogenetic tools to study and to modify neuronal function

Advertising institute: ICS-4 - Cellular Biophysics
Reference number: D003/2016, Biology, chemistry, physics

The laboratory of Christoph Fahlke in the Institute of Complex Systems – Cellular Biophysics is looking for a

PhD student

with a DFG-founded thesis project that aims at identifying novel optogenetic tools to study and to modify neuronal function. Available methods range from cell culture, molecular biology, fluorescence spectroscopy and microscopy to cellular electrophysiology. We are looking for highly motivated individuals with an interest and/or experience in cell biology and optics. The position is available for three years.

Our laboratory focuses on the molecular and cellular function of membrane transport proteines (PNAS (2006) 103: 11411-11416; J Biol Chem (2015) 290, 25851-25862, PNAS (2013) 110, 12486-12491, Cell 160, 542-553) and on their dysfunction in genetic and acquired human diseases (Am J Hum Genet (2009) 85, 273-280; Brain (2012) 135, 3416-3425, Nature Genet (2013) 45, 1050-1054). We use multiple approaches ranging from computational biology on individual proteins to the analysis of organ functions in animal models.


  • M. Sc. (or equivalent) in biology, chemistry, physics, or a related field
  • Experience in molecular and cellular biophysics
  • Excellent technical and organizational skills
  • Willingness to communicate research results and to interact within an international research environment
  • The integration in international co-operations requires the ability to cooperate in an international team, thus good skills in the spoken and written English.

Equal opportunity is a cornerstone of our staff policy. Applications from disabled persons are welcomed. Payment of the PhD fellow will be based on salary grade 13/2 Collective Agreement for the Civil Service (TVöD).

Please send applications (preferably via E-mail) with a motivation letter, a curriculum vitae, a summary of the results of the diploma/master thesis, the methods used so far, and copies of all relevant certificates to:

Christoph Fahlke, MD
Institute of Complex Systems, Zelluläre Biophysik (ICS-4)
Forschungszentrum Jülich
52428 Jülich

Tel: 02461-613016;
Fax: 02461-614216