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Advertising division: IBG-1 - Biotechnology
Reference number: D085/2018, Biotechnology, Computational Science

PhD project: Simulation based support of bioreactor design across lab and industrial scales for cultivation of microorganisms under comparable conditions

At IBG-1: Biotechnology, bioreactors of various types and dimensions are operated to cultivate microorganisms and produce valuable substances. It is of particular interest how such reactors need to be designed and operated in order to ensure the transferability of results from lab reactors at liter scale to production reactors at industrial large scale.

The advertised PhD project targets to support the design of bioreactors across scales and the cultivation of microorganisms under comparable conditions with simulation models. This requires to couple a commercial CFD (Computational Fluid Dynamics) simulator with metabolic cell models. Turbulent flow in a stirred reactor is calculated, and concentration profiles of solved substrates and products are determined along the trajectories of selected representative organisms.

The project requires solid methods knowledge and practical application experience with CFD simulation, ideally using COMSOL. Fundamental knowledge of metabolic modeling are desirable but can be acquired on the job. Good command of the English language is mandatory.

We offer an international and interdisciplinary research environment and work with modern methods on recent and relevant questions of life sciences. In addition to a solid fundamental education a high sense of responsibility and team spirit are expected. The PhD position is open at the next possible date.

Forschungszentrum Jülich aims to employ more women in this area and therefore particularly welcomes applications from women. We also welcome applications from disabled persons.

Your contact person is Dr. Eric von Lieres,

Dr. Eric von Lieres
Forschungszentrum Jülich
Institute of Bio- and Geosciences
IBG-1: Biotechnology