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Advertising division: ER-C-3 - Structural Biology
Reference number: 2019-051

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The Ernst Ruska-Centre (ER-C) at the Forschungszentrum Jülich houses some of the world's most advanced electron microscopes and tools for nanocharacterisation. The scientific research covers current issues in condensed matter physics and from now on cryo-EM on biomacromolecules and in the future development of electron microscopy. The ER-C has a total of 13 electron microscopes including the PICO FEI Titan with a point resolution of 0.5 Å. The facility has been extended with state-of-the-art cryo-microscopes FEI Talos Arctica including Bioquantum K3 and FEI Talos 120. The Structural Biology subinstitute of the ER-C investigates the structural and molecular mechanism of autophagy and pushes the development of cryo-EM related methodology. The Jülich campus hosts a vibrant electron microscopy, biophysics and structural biology community.

We are looking to recruit a

Structural biology scientist for protein purification

Your Job:

  • Cloning, expression and purification of recombinant proteins and macromolecular complexes
  • Overseeing multiple expressions systems, such as E.coli, insect cell culture and human cell culture
  • Functional and biophysical characterization of purified proteins
  • Screening, data acquisition and structure determination of purified cryo-EM samples


Your Profile:

  • University degree (master or doctorate) in physics, chemistry, biology, Computer science or related field
  • Several years of experience in structural biology related protein purification
  • Excellent communication and interpersonal skills as well as the ability to interact effectively with team members and users are essential
  • Experience with multiple protein expression systems so that (s)he can help other users and establish new purification procedures for macromolecular complexes
  • Participating in generating highly pure samples for cryo-EM structural investigation of autophagy complexes at the ER-C3 for structural biology
  • Fluency in English is required


Our Offer:

  • Exciting working environment on an attractive research campus with excellent infrastructure, located between the cities of Cologne, Düsseldorf, and Aachen
  • International and interdisciplinary working atmosphere
  • A comprehensive further training programme
  • Flexible working hours and various opportunities to reconcile work and private life
  • Limited for 2 years with possible longer-term prospects
  • Full-time position with the option of slightly reduced working hours
  • Salary and social benefits in conformity with the provisions of the Collective Agreement for the Civil Service (TVöD)


Forschungszentrum Jülich aims to employ more women in this area and therefore particularly welcomes applications from women.

We also welcome applications from disabled persons.

Additional Information

We look forward to receiving your application, preferably online via our online recruitment system on our career site until 05.03.2019, quoting the above-mentioned reference number.

Questions about the vacancy?
Contact us by mentioning the reference number 2019-051: career@fz-juelich.de
Please note that for technical reasons we cannot accept applications via email.