Databases, Ontology and Tool Development
The group is involved in develop tools to faster evaluate, interpret and visualize omics data.
The group is involved in develop tools to faster evaluate, interpret and visualize omics data. Major tools the group has developed are MapMan a GUI application to visualize omics data on biological pathways. ROBINa is a graphical frontend to BioConductor/R. It allows you to quality control and visualize microarray and RNASeq data. In addition experimental questions can be formulated by visually drawing experiments and the data is then statistically evaluated using state-of-the-art statistical algorithms developed in R. All these tools are supported by forums.
Within the MapMan tool we have also developed a specific ontology to support the annotation of genes and metabolites for plant omics data. This onotology has been expanded to more than 10 plant species and can be applied to any plant species where transcript data is available based on sequence similarity searches. We thus provide an easy way to learn about plant transcriptome projects.
Also the group hosts the GABI PRIMARY database. A database for primary data generated within the BMBF financed German GABI programs.