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Veröffentlichungen 2013

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Rho-kinase: regulation, (dys)function, and inhibition
Biological chemistry 394(11), 1399-1410 (2013) [10.1515/hsz-2013-0181]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Double-strand DNA end-binding and sliding of the toroidal CRISPR-associated protein Csn2
Nucleic acids symposium series 41(12), 6347 - 6359 (2013) [10.1093/nar/gkt315]  GO OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Thermodynamic analysis of structural transitions during GNNQQNY aggregation
Proteins 81(7), 1141 - 1155 (2013) [10.1002/prot.24263]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Analysis of prion protein aggregates in blood and brain from pre-clinical and clinical BSE cases
Veterinary microbiology 166(1-2), 102 - 108 (2013) [10.1016/j.vetmic.2013.05.021]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Prion diagnostics by single particle detection and quantitation
Prion 7 (suppl), 1-9 (2013) BibTeX | EndNote: XML, Text | RIS

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Collision-induced dissociation studies of caffeine in positive electrospray ionisation mass spectrometry using six deuterated isotopomers and one N1-ethylated homologue
Rapid communications in mass spectrometry 27(8), 885 - 895 (2013) [10.1002/rcm.6520]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Structure and dynamics of human Nedd4-1 WW3 in complex with the αENaC PY motif
Biochimica et biophysica acta / Proteins and proteomics 1834(8), 1632 - 1641 (2013) [10.1016/j.bbapap.2013.04.031]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Energy barriers and driving forces in tRNA translocation through the ribosome
Nature structural & molecular biology 2690, 1-8 (2013) [10.1038/nsmb.2690]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Structural biology: Active arrestin proteins crystallized
Nature 497(7447), 45-46 (2013) [10.1038/nature12096]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Visualizing GroEL/ES in the Act of Encapsulating a Folding Protein
Cell 153(6), 1354-1365 (2013) [10.1016/j.cell.2013.04.052]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Assembling an ion channel: ORF 3a from SARS-CoV
Biopolymers 99(9), 628 - 635 (2013) [10.1002/bip.22230]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes
Human molecular genetics 22(2), 262 - 270 (2013) [10.1093/hmg/dds426]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Small-angle X-ray Scattering of Apolipoprotein A-IV Reveals the Importance of Its Termini for Structural Stability
The journal of biological chemistry 288(7), 4854 - 4866 (2013) [10.1074/jbc.M112.436709]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Structural and functional characterization of the recombinant death domain from death-associated protein kinase.
PLoS one 8(7), e70095 (2013) [10.1371/journal.pone.0070095] OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by Pubmed Central Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Full-length Vpu and human CD4(372–433) in phospholipid bilayers as seen by magic angle spinning NMR
Biological chemistry 394(11), 1453 - 1463 (2013) [10.1515/hsz-2013-0194]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Characterization of a single-chain variable fragment recognizing a linear epitope of Aß: A biotechnical tool for studies on Alzheimer's disease?
PLoS one 8(3), e59820 (2013) [10.1371/journal.pone.0059820] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum
Biochemical pharmacology 85(1), 38 - 45 (2013) [10.1016/j.bcp.2012.10.006]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The Off-rate of Monomers Dissociating from Amyloid-ß Protofibrils
The journal of biological chemistry 288(52), 37104 - 37111 (2013) [10.1074/jbc.M113.513432]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Structural insights into the proton pumping by unusual proteorhodopsin from nonmarine bacteria
Proceedings of the National Academy of Sciences of the United States of America 110(31), 12631 - 12636 (2013) [10.1073/pnas.1221629110]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Two Distinct States of the HAMP Domain from Sensory Rhodopsin Transducer Observed in Unbiased Molecular Dynamics Simulations
PLoS one 8(7), e66917 - (2013) [10.1371/journal.pone.0066917] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Protein structure prediction using global optimization by basin-hopping with NMR shift restraints
The journal of chemical physics 138(025102), 1-7 (2013) [10.1063/1.4773406]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Ground state structure of D75N mutant of sensory rhodopsin II in complex with its cognate transducer
Journal of photochemistry and photobiology / B 123, 55 - 58 (2013) [10.1016/j.jphotobiol.2013.03.008]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The Crystal Structures of the Eukaryotic Chaperonin CCT Reveal Its Functional Partitioning
Structure 21(4), 540-549 (2013) [10.1016/j.str.2013.01.017]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Structural and functional characterisation of TesA - a novel lysophospholipase A from Pseudomonas aeruginosa.
PLoS one 8(7), e69125 - (2013) [10.1371/journal.pone.0069125] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Highlight: NRW Research School BioStruct – Biological Structures in Molecular Medicine and Biotechnology
Biological chemistry 394(11), 1353-1355 (2013) [10.1515/hsz-2013-0250]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Expression and Purification of Functional Human Mu Opioid Receptor from E.coli
PLoS one 8(2), e56500 - (2013) [10.1371/journal.pone.0056500] OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Molecular interaction of the cellular and pathogenic PrP describes the species barrier in prion diseases
Prion 7, 82-83 (2013) BibTeX | EndNote: XML, Text | RIS

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Seeded Fibrillation as Molecular Basis of the Species Barrier in Human Prion Diseases
PLoS one 8(8), e72623 - (2013) [10.1371/journal.pone.0072623] OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Interaction of Bcl-2 with the autophagy-related GABAA receptor-associated protein (GABARAP): biophysical characterization and functional implications
The journal of biological chemistry 288, 37204-37215 (2013) [10.1074/jbc.M113.528067]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Expression and characterisation of fully posttranslationally modified cellular prion protein in Pichia pastoris
Biological chemistry 394(11), 1475-1483 (2013) [10.1515/hsz-2013-0180]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba
Nature Chemical Biology 9(1), 37 - 42 (2012) [10.1038/nchembio.1116]  GO   Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Nanodiscs Allow Phage Display Selection for Ligands to Non-Linear Epitopes on Membrane Proteins
PLoS one 8(9), e72272 - (2013) [10.1371/journal.pone.0072272] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Aaptamine Derivatives from the Indonesian Sponge Aaptos suberitoides
Journal of natural products 76(1), 103 - 106 (2013) [10.1021/np300794b]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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New Cytotoxic 1,2,4-Thiadiazole Alkaloids from the Ascidian Polycarpa aurata
Organic letters 15(9), 2230–2233 (2013) [10.1021/ol400791n]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

(Corresponding Author)
Aggregation of Amyloids at Biomembranes and its Implications in Alzheimers's Disease and Type II Diabetes
Biophysical journal 104(2), 592a - (2013) [10.1016/j.bpj.2012.11.3291]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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How the amyloid-β peptide and membranes affect each other: An extensive simulation study
Biochimica et biophysica acta / Biomembranes 1828(2), 327 - 339 (2013) [10.1016/j.bbamem.2012.09.001]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Stability of Transmembrane Amyloid ß-Peptide and Membrane Integrity Tested by Molecular Modeling of Site-Specific Aß$_{42}$ Mutations
PLoS one 8(11), e78399 (2013) [10.1371/journal.pone.0078399] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Membrane Permeation Induced by Aggregates of Human Islet Amyloid Polypeptides
Biophysical journal 105, 2323-2332 (2013) [10.1016/j.bpj.2013.09.045]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae “Short” Light, Oxygen, Voltage (LOV) Protein Family: Implications for the Design of LOV-Based Optogenetic Tools
Biochemistry 52(26), 4460 - 4473 (2013) [10.1021/bi400311r]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Cross-validation in cryo-EM-based structural modeling
Proceedings of the National Academy of Sciences of the United States of America 110(22), 8930-8935 (2013) [10.1073/pnas.1119041110]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Structural snapshot of cyclic nucleotide binding domains from cyclic nucleotide-sensitive ion channels.
Biological chemistry 394(11), 1439–1451 (2013) [10.1515/hsz-2013-0228]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Interaction of Nonstructural Protein 5A of the Hepatitis C Virus with Src Homology 3 Domains Using Noncanonical Binding Sites
Biochemistry 52, 6160-6168 (2013) [10.1021/bi400363v]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Molecular modeling, dynamics, and an insight into the structural inhibition of cofactor independent phosphoglycerate mutase isoform 1 from Wuchereria bancrofti using cheminformatics and mutational studies
Journal of biomolecular structure & dynamics 31(7), 765-778 (2013) [10.1080/07391102.2012.709460] BibTeX | EndNote: XML, Text | RIS

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BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins.
Journal of biomolecular NMR 55, 311-321 (2013) [10.1007/s10858-013-9715-0]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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An N-terminal amphipathic helix in the Dengue virus nonstructural protein 4A mediates oligomerization and is essential for replication.
Journal of virology 87(7), 4080-4085 (2013) [10.1128/JVI.01900-12]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase independent manner
The journal of biological chemistry -, - (2013) [10.1074/jbc.M113.532333]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division
Biological chemistry 394(11), 1411-1423 (2013) [10.1515/hsz-2013-0184]  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Treatment of D3 removes amyloid deposits, reduces inflammation, and improves cognition in aged APP/PS1 double transgenic mice.
Alzheimer disease & associated disorders 34(3), 609-620 (2013) [10.3233/JAD-121792] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Expression, Purification, and Solid-State NMR Characterization of the Membrane Binding Heme Protein Nitrophorin 7 in Two Electronic Spin States
Biochemistry 52(40), 7031 - 7040 (2013) [10.1021/bi401020t]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Structural features of antiviral DNA cytidine deaminases
Biological chemistry 394(11), 1357 - 1370 (2013) [10.1515/hsz-2013-0165]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The Amyloid-β Oligomer Count in Cerebrospinal Fluid is a Biomarker for Alzheimer's Disease
Journal of Alzheimer's disease 34(4), 985-994 (2013) [10.3233/JAD-122047] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Identification of key residues involved in adrenomedullin binding to the AM 1 receptor
British journal of pharmacology 169(1), 143 - 155 (2013) [10.1111/bph.12118]  GO OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Revisiting Disrupted-in-Schizophrenia 1 as a scaffold protein
Biological chemistry 394(11), 1425-1437 (2013) [10.1515/hsz-2013-0178]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS


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