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Querschnitt durch die Fibrille
Sharpest Image of Alzheimer’s Fibrils Shows Previously Unknown Details (Science)
7 September 2017 – A team of researchers from Germany and the Netherlands have determined the structure of an amyloid fibril with previously unachieved resolution. The atomic-level three-dimensional structure elucidated by scientists displays previously unknown structural details which can answer many questions on the growth of harmful deposits and also explain the effect of genetic risk factors.
More: Sharpest Image of Alzheimer’s Fibrils Shows Previously Unknown Details (Science) …

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Autophagie (Platzhalter)

Autophagy

Autophagy is a highly conserved mechanism in eukaryotes to degrade cellular components. Autophagy plays an important role both in the baseline turnover of intracellular proteins and organelles, as well as in the production of amino acids under starvation conditions. We investigate proteins that are involved in this process. More: Autophagy …

Alzheimer2

Alzheimer′ s Disease

Alzheimer´s disease is a progressive, neurodegenerative disorder and the most common type of dementia. Currently more than 24 million people are affected worldwide. Our research focusses on developing methods for pre-symptomatic diagnosis and new therapeutic approaches. More: Alzheimer′ s Disease …

NMR-Teaser

Biomolecular NMR Center

The Biomolecular NMR Center, which is jointly run by the Institute of Physical Biology at HHU Düsseldorf and the ICS-6, operates various high-field NMR machines and provides an excellent environment for liquid and solid state NMR spectroscopy for structural biology on biologically and medically relevant proteins. More: Biomolecular NMR Center …


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