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Brain Network Modeling

Modellierung kortikaler Systeme



Our team investigates regional specialization and large-scale integration in the human brain. For this task we use both psychological experiments on cognitive functions as well as multimodal modeling of structure, function and connectivity.


Research Focus:

 

  • Functional imaging and analysis

    • Psychological experiments of cognition
    • Meta-Analysis of imaging data
    • Combining probabilistic cytoarchitectonic maps and functional imaging data
    • Aging, inter-individual variance
  • Connectivity analyses

    • Effektive Connektivity (DCM)
    • Functional task-based Connectivity (MACM)
    • Functional task-independent Connectivity (Resting-State)
    • Anatomical Connectivity (DTI)
  • Methods development

    • Data-Mining

      • Data-driven cortical parcellation
      • Identification of sub-groups
    • Toolboxes for multimodal imaging
  • Pathophysiological investigation of

    • Schizophrenia
    • Depression
    • Parkinson Syndrome)



Selected publications:

Rottschy C, Langner R, Dogan I, Reetz K, Laird AR, Schulz JB, Fox PT, Eickhoff SB. 2012. Modelling neural correlates of working memory: a coordinate-based meta-analysis. Neuroimage. 60(1):830-46.

Bzdok D, Laird AR, Zilles K, Fox PT, Eickhoff SB. 2012. An investigation of the structural, connectional, and functional subspecialization in the human amygdala. Hum Brain Mapping (in press)

Cieslik EC, Caspers S, Roski C, Kellermann TS, Jakobs O, Langner R, Laird AR, Fox PT, Eickhoff SB. 2012. Is There "One" DLPFC in Cognitive Action Control? Evidence for Heterogeneity From Co-Activation-Based Parcellation. Cerebral Cortex (in press)

Eickhoff SB, Bzdok D, Laird AR, Roski C, Caspers S, Zilles K, Fox PT. 2011Co-activation patterns distinguish cortical modules, their connectivity and functional differentiation. Neuroimage. 57(3):938-49

Jakobs O, Langner R, Caspers S, Roski C, Cieslik EC, Zilles K, Laird AR, Fox PT, Eickhoff SB. 2012. Across-study and within-subject functional connectivity of a right temporo-parietal junction subregion involved in stimulus-context integration. Neuroimage.60(4):2389-98

Müller VI, Cieslik EC, Turetsky BI, Eickhoff SB. 2012. Crossmodal interactions in audiovisual emotion processing. Neuroimage. 60(1):553-61

Clos M, Langner R, Meyer M, Oechslin MS, Zilles K, Eickhoff SB. 2012. Effects of prior information on decoding degraded speech: an fMRI study. Human Brain Mapping (in press)

Eickhoff SB, Jbabdi S, Caspers S, Laird AR, Fox PT, Zilles K, Behrens TE. 2010. Journal of  Neuroscience. 30(18):6409-21.





Datasets:

Clos M, Amunts K, Laird AR, Fox PT, Eickhoff SB. 2013. Tackling the mutlifunctional nature of Broca's region meta-analytically: Co-activation-based parcellation of area 44. Neuroimage (Advance online publication). doi: 10.1016/j.neuroimage.2013.06.041.

[Download]

The zip file contains the nifti files of the five CBP-derived clusters (normalized to MNI space) numbered correspondingly to the parcellation described in the paper.

Additional Information

Groupleader

Prof. Dr. med. Simon Eickhoff

Institut für Neurowissenschaften und Medizin (INM-1)
Forschungszentrum Jülich
52425 Jülich
Tel.:  +49 (0)2461 61 8609
Fax: +49 (0)2461 61 3483
s.eickhoff@fz-juelich.de

and

Institut für Klinische Neurowissenschaften und Medizinische Psychologie
Heinrich-Heine Universität Düsseldorf
40225 Düsseldorf

Tel.: +49 (0)211 81 13018
E-Mail: simon.eickhoff@uni-duesseldorf.de

Management

Stefanie Hennen

Building: 15.9, Room: 3021

+49 2461 61-2412
 +49-2461 61-3483
s.hennen@fz-juelich.de

Janine Klapper

Building: 15.9, Room: 3020

+49 2461 61-6443
+49 2461 61-3483
j.klapper@fz-juelich.de

Address

Institut für Neurowissenschaften und Medizin (INM-1)
Forschungszentrum Jülich
52425 Jülich

Building: 15.9


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