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Aktuelle Publikationen

MR-Physik

Oros-Peusquens A.M., Matusch A., Sabine Becker J., Shah N. J. (2011). Automatic segmentation of tissue sections using the multielement information provided by LA-ICP-MS imaging and k-means cluster analysis. International Journal of Mass Spectrometry special issue "Bioinorganic Mass Spectrometry and Metallomics" (in print)

Stöcker T, Vahedipour K, Pflugfelder D, Shah NJ. High Performance Computer MRI Simulations. Magnetic Resonance in Medicine. 2010; 64:186–193.

I. Neuner, Y. Kupriyanova, T. Stöcker, R. Huang, O. Posnansky, F. Schneider, M. Tittgemeyer, N. J. Shah. White Matter Abnormalities in Tourette Syndrome Extend Beyond Motor Pathways. NeuroImage 2010: 51:1184-1193.

K. Ulrich, P. Galvosas, J. Kaerger, F. Grinberg, J. Vernimmen, V. Meynen, P. Cool, Self-Assembly and Diffusion of Block Copolymer Templates in SBA-15 Nanochannels, J. Phys. Chem., B 114, 4223-4229, (2010).

A.M. Oros-Peusquens, T. Stöcker, K. Amunts, K. Zilles, N.J. Shah (2010). In vivo imaging of the human brain at 1.5T with 0.6 mm isotropic resolution. Magnetic Resonance Imaging, 28: 329-340.

Salber D, Stoffels G,Oros-Peusquens AM, Shah NJ, Reifenberger G, Hamacher K, Coenen HH, Langen KJ (2010). Comparison of O-(2-18F-fluoroethyl)-L-tyrosine and L-3H-methionine uptake in cerebral hematomas. J Nucl Med. 51:790-7.

N.J. Shah, V. Ermer, A.M. Oros-Peusquens. Measuring the Absolute Water Content of the Brain Using Quantitative MRI. Book Chapter, Neuroimaging Protocols, Editor M. Modo, in print

Kellermann T, Reske M, Jansen A, Satrapi P, Shah NJ, Schneider F, Habel U. Latencies in BOLD response during visual attention processes. Brain Research Cognitive Brain Research, in Druck.

MR-PET

Herzog H, Langen KJ, Weirich C, Rota Kops E, Kaffanke J, Tellmann L, Scheins J, Neuner I, Stoffels G, Fischer K, Caldeira L, Coenen HH, Shah NJ. High Resolution BrainPET Combined with Simultaneous MRI. Nuklearmedizin/NuclearMedicine 2011 50(2) 74-82.

Miese Falk; Scherer Axel; Ostendorf Benedikt; Heinzel Alexander; Lanzman Rotem S; Kropil Patric; Blondin Dirk; Hautzel Hubertus; Wittsack Hans-Jorg; Schneider Matthias; Antoch Gerald; Herzog Hans; Shah N Jon. Hybrid (18)F-FDG PET -MRI of the hand in rheumatoid arthritis: initial results.Clinical rheumatology, (2011 Sep) Vol. 30, No. 9, pp. 1247-50.

Tellmann L, Quick HH, Bockisch A, Herzog H, Beyer T. The effect of MR surface coils on PET quantification in whole-body PET/MR: Results from a pseudo-PET/MR phantom study. Medical Physics 2011 38:2795-2805

Herzog H, Langen KJ, Kaffanke J, Weirich C, Neuner I, Stoffels G, Rota Kops E, Scheins J, Tellmann L, Shah NJ. MR-PET opens new horizons in neuroimaging. Future Neurol 2010 5(6): 807–815

Herzog H, Pietrzyk U, Shah NJ, Ziemons K. The current state, challenges and perspectives of MR-PET. NeuroImage 2010;49:2072-83

Neuner I, Kaffanke JB, Kupriyanova Y, Langen JF, Herzog H, Shah NJ. Trimodal imaging in one session: FET-PET, MP-RAGE and DTI in humans. NeuroImage Supplement Human Brain Mapping 2010

fMRI

Neuner I, Kellermann T, Stöcker T, Kircher T, Habel U, Shah NJ, Schneider F. Amygdala Hypersensitivity in Response to Emotional Faces in Tourette’s Patients. World J Biological Psychiatry in press SWBP-2009-0112.R2 IP 3.58

Habel U, Pauly K, Koch K, Kellermann T, Reske M, Backes V, Stöcker T, Amunts K, Shah NJ, Schneider F. Emotion-cognition interactions in schizophrenia. In Press (Psychological Medicine)

Neuner I, Stöcker T, Kellermann T, Ermer V, Wegener HP, Eickhoff SB, Schneider F, Shah NJ. Electrophysiology Meets fMRI: Neural Correlates of the Startle Reflex Assessed by Simultanueous EMG-fMRI Data Acquisition. Human Brain Mapping 2010 epub ahead of print, DOI: 10.1002/hbm.20965, IP 5.395

Mobascher A, Brinkmeyer J, Thiele H, Toliat MR, Steffens M, Warbrick T, Musso F, Wittsack H-J, Saleh A, Schnitzler A, Winterer G. The val158met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation. Molecular Pain, 2010, 6: 32

Reske M, Kellermann T, Shah NJ, Schneider F, Habel U. The Impact of Valence and Age on Olfactory Induced Cerebral Activation in Healthy Females. Behavioral Neuroscience, 2010, 124(3): 414-422.

Neuner I, Kupriyanova Y, Stöcker T, Huang R, Posnansky O, Schneider F, Tittgemeyer M, Shah NJ. White matter abnormalities in Tourette Syndrome Extend Beyond Motor Pathways. Neuroimage 2010, 51:1184-1193, IP 5.694

Brinkmeyer J, Mobascher A, Warbrick T, Musso F, Wittsack HJ, Saleh A, Schnitzler A, Winterer, G. Dynamic EEG-informed fMRI modeling of the pain matrix using 20-ms root mean square segments. Human Brain Mapping, 2010, DOI: 10.1002/hbm/20967

Musso F, Brinkmeyer J, Mobascher A, Warbrick T, Winterer G. Spontaneous brain activity and EEG microstates. A novel EEG/fMRI analysis approach to explore resting-state networks. Neuroimage, 2010, 52(4): 1149-61.

Habel U, Koch K, Kellermann T, Reske M, Frommann N, Wölwer W, Zilles K, Shah NJ, Schneider F. Training of affect recognition in schizophrenia: neurobehavioral validation. Social Neuroscience, 2010, 5(1): 92-104.

Mobascher A, Brinkmeyer J, Warbrick T, Musso F, Schlemper V, Wittsack HJ, Saleh A, Schnitzler A, Winterer G. Brain activation patterns underlying fast habituation to painful laser stimuli. Internaltional Journal of Psychophysiology, 2010, 75(1): 16-24.

PET-Physik

Hautzel H, Müller HW, Herzog H, Grandt R. Cognition-induced modulation of serotonin in the orbitofrontal cortex: A controlled cross-over PET study of a delayed match-to-sample task using the 5-HT2a receptor antagonist [18F]altanserin. NeuroImage 2011 58:905-911

Lubberink M, Hans Herzog H. Quantitative imaging of 124I and 86Y with PET. Eur J Nucl Med Mol Imaging. 2011 38 (Suppl1) S10-S18

Piroth MD, Holy R, Pinkawa M, Stoffels G, Kaiser HJ, Galldiks N, Herzog H, Coenen HH, Eble MJ, Langen KJ. Prognostic impact of postoperative, pre-irradiation 18F-Fluoroethyl-L-Tyrosine uptake in glioblastoma patients treated with radiochemotherapy. Radiotherapy and Oncology, 2011 80:176-184

Scheins JJ, Herzog H, Shah NJ. Fully-3D PET image reconstruction using scanner-independent, adaptive projection data and highly rotation-symmetric voxel assemblies. IEEE Trans Med Imaging. 2011 30:879-92.

MEG-Physik

Dammers J, Breuer L, Axer M, Kleiner M, Eiben B, Gräßel D, Dickscheid T, Zilles K, Amunts K, Shah N. Joni, Pietrzyk U. Automatic identification of gray and white matter components in polarized light imaging. Neuroimage 59,2 (2012) 1338–1347
http://dx.doi.org/10.1016/j.neuroimage.2011.08.030

Dammers J and Schiek M. 2011. Detection of Artifacts and Brain Responses Using Instantaneous Phase Statistics in Independent Components. In Magnetoencephalography, ed. W Pang, Elizabeth, InTech; 131-150.
Detection of Artifacts and Brain Responses Using Instantaneous Phase Statistics in Independent Components.

M. Axer, D. Gräßel, C. Palm, J. Dammers, H. Axer, K. Amunts, U. Pietrzyk, K. Zilles. High-resolution fiber tract reconstruction in the human brain by means of three-dimensional polarized light imaging (3D-PLI). Frontiers in Neuroinformatics 5, 34 (2011)
http://dx.doi.org/10.3389/fninf.2011.00034

Weidner R., Boers F., Mathiak K., Dammers J., Fink G.R. The temporal dynamics of the Müller-Lyer illusion. Cerebral Cortex, 1586-1595, 2010
The temporal dynamics of the Müller-Lyer illusion.

Palm C, Axer M, Gräßel D, Dammers J, Lindemeyer J, Zilles K, Pietrzyk U, Amunts K. Towards ultra-high resolution fibre tract mapping of the human brain – registration of polarised light images and reorientation of fibre vectors. Front. Hum. Neurosci. (2010)
Towards ultra-high resolution fibre tract mapping of the human brain

Axer M, Amunts K, Gräßel D, Palm C, Dammers J, Axer H, , Pietrzyk U, K. Zilles. (2011) A Novel Approach to the Human Connectome: Ultra-High Resolution Mapping of Fiber Tracts in the Brain. Neuroimage, Vol 54(2), 1091-1101

Dammers, J., Axer, M., Grässel, D., Palm, C., Zilles, K., Amunts, K., et al. (2010). Signal enhancement in polarized light imaging by means of independent component analysis. Neuroimage, 49(2), 1241-8.

Thönnessen H., Boers F., Dammers J., Chen Y-H., Norra C., Mathiak K (2010). Early sensory encoding of affective prosody: Neuromagnetic tomography of emotional category changes. Neuroimage, 250-259

Chen Yu-Han, Edgar J. Christopher, Holroyd Tom, Dammers Jürgen, Thönneßen Heike, Roberts Timothy P.L., Mathiak Klaus (2010). Neuromagnetic oscillations to emotional faces and prosody. European Journal of Neuroscience, Vol. 31, pp. 1818–1827, 2010

Florin E, Gross J, Reck C, Maarouf M, Schnitzler A, Sturm V, Fink GR, Timmermann, Lars (2010). Causality between local field potentials of the subthalamic nucleus and electromyograms of forearm muscles in Parkinson’s disease. European Journal of Neuroscience, Vol31, Issue 3, 491–498

Hirntumore

Abdulazim A, Samis Zella MA, Rapp M, Gierga K, Langen KJ, Steiger HJ, Sabel M.Meningioangiomatosis in a patient with progressive focal neurological deficit-case report and review of literature. Br J Neurosurg. 2012 Nov 20

Kirch RD, Meyer PT, Klein S, Braun F, Gehrig S, Langen KJ, von Hörsten S, Nikkhah G, Cassel JC, Döbrössy MD.
Early deficits in declarative and procedural memory dependent behavioral function in a transgenic rat model of Huntington's disease.Behav Brain Res. 2012 Nov 5

Galldiks N, Rapp M, Stoffels G, Fink GR, Shah NJ, Coenen HH, Sabel M, LangenKJ. Response assessment of bevacizumab in patients with recurrent malignant glioma using [18F]Fluoroethyl-l-tyrosine PET in comparison to MRI. European Journal of Nuclear Medicine and Molecular Imaging 2012

Galldiks N, Langen KJ. Anwendung von Aminosäuren-PET in der Diagnostik und Therapie von zerebralen Tumoren. Fortschr Neurol Psychiatr. 2012 Jan;80(1):17-23

Piroth MD, Pinkawa M, Holy R, Klotz J, Schaar S, Stoffels G, Coenen HH, Kaiser JH, Langen KJ, Eble MJ. Integrated-Boost-IMRT with FET-PET-adapted local dose escalation in glioblastomas - Results of a prospective Phase-II-study. Strahlenther Onkol. 2012;188:334-339.

Heinzel A, Stock S, Langen KJ, Müller D. Cost-effectiveness analysis of amino acid PET guided surgery for supratentorial high-grade gliomas. J Nucl Med, 2012; 53:552-558

Heinzel A, Stock S, Langen KJ, Müller D. Cost-effectiveness analysis of FET PET guided target selection for the diagnosis of gliomas. EJNMMI, 2012; 39:1089-96

Cornelius JF, Langen KJ, Stoffels G, Hänggi D, Sabel M Steiger JH. PET imaging of meningioma in clinical practice– Review of literature and future directions.
J Neurosurgery 2012 ;70:1033-41

Döbrössy MD, Deininger F, Klein S, Garcia J, Langen KJ, Weber WA, Nikkhah G, Meyer PT. [18F]desmethoxyfallypride as a novel PET radiotracer for quantitative in vivo dopamine D2/D3 receptor imaging in rat models of neurodegenerative diseases. Nucl Med Biol. 2012 May 14. [Epub ahead of print] PubMed PMID: 22591915.

Manook A, Yousefi BH, Willuweit A, Platzer S, Reder S, Voss A, Huisman M, Settles M, Neff F, Velden J, Schoor M, von der Kammer H, Wester HJ, Schwaiger M, Henriksen G, Drzezga A. Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease. PLoS One. 2012;7(3):e31310

Langen KJ. Molecular Imaging of Brain Tumors. Neuromethods, 1, Volume 71, Molecular Imaging in the Clinical Neurosciences, Seiten 345-357. Springer-Verlag GmbH Heidelberg DOI: 10.1007/7657_2012_42

Galldiks N, Langen KJ, Holy R, Pinkawa M, Stoffels G, Kaiser HJ, Filss CP, Fink GR, Coenen HH, Eble MJ, Piroth MD. Assessment of treatment response in patients with glioblastoma multiforme using [18F]Fluoroethyl-L-Tyrosine PET. J Nucl Med 2012;53:1048-57

Stuplich M, Hadidzadeh DR, Kuchelmeister K, Scorzin J, Filß C, Langen KJ, Schäfer N, Mack F ,Schüller H, Simon M, Glas M, Pietsch T, Urbach H, Herrlinger U, Late pseudoprogression in glioblastoma patients treated with lomustine and temozolomide. J Clin Oncol. 2012;30:e180-3

Neuner I, Kaffanke JB, Langen KJ, Rota Kops E, Tellmann L, Stoffels G, Weirich C, Filss C, Scheins J, Herzog H, Shah NJ. Multimodal Imaging Utilising Simultaneous MR-PET For Human Brain Tumour Assessment – Eur Radiol 2012 Jul 11. [Epub ahead of print] PubMed PMID: 22777617.

Galldiks N, Stoffels G, Filss CP, Sabel M, Piroth MD, Ruge MI, Fink GRF, Coenen HH, Langen KJ. Role of [18F]Fluoroethyl-L-Tyrosine PET for differentiation of radiation necrosis from recurrent brain metastasis FET PET in Brain metastases. J Nucl Med. 2012 Aug 7. [Epub ahead of print] PubMed PMID: 22872742.

Piroth MD, Pinkawa M, Holy R, Klotz J, Nussen S, Stoffels G, Coenen HH, Kaiser JH, Langen KJ, Eble MJ. Prognostic Value of Early 18F-Fluoroethyltyrosine PET after Radiochemotherapy in Glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2011;80:176-84


Langen KJ, Müller HW, Eble M, Steiger HJ. Stellungnahme zum Bericht des IQWiG zum Nutzen der PET und PET/CT zur Rezidivdiagnostik bei Gliomen mit hohem Malignitätsgrad. Journal Onkologie 2011;1:37-39


Floeth FW, Sabel M, Ewelt C, Stummer W, Felsberg J, Reifenberger G, Steiger HJ, Stoffels G, Coenen HH, Langen KJ. Comparison of 18F-FET-PET and 5-ALA fluorescence in cerebral gliomas. Eur J Nucl Med Mol Imaging 2011;38:731-41


Herzog H, Langen KJ, Weirich C, Rota Kops E, Kaffanke J, Tellmann L, Scheins J, Neuner I, Stoffels G, Fischer K, Caldeira L, Coenen HH, Shah NJ. High Resolution BrainPET Combined with Simultaneous MRI. Nuklearmedizin 2011;50:74-82.


Piroth MD, Holy R, Pinkawa M, Stoffels G, Kaiser JH, Galldiks N, Herzog H, Coenen HH, Eble MJ, Langen KJ. Prognostic impact of postoperative 18F-Fluoroethyl-L-Tyrosine uptake in patients with glioblastoma multiforme. Radiother Oncol. 2011;99:218-24

Ewelt C, Floeth FW, Felsberg J, Steiger HJ, Sabel M, Langen KJ, Stoffels G, Stummer W. Finding the anaplastic focus in diffuse gliomas: The value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence. Clinical Neurology and Neurosurgery, 2011;113:541-7


Langen KJ, Bartenstein P, Boecker H, Brust P, Coenen HH, Drzezga A, Grünwald F, Krause BJ, Kuwert T, Sabri O, Tatsch K, Weber WA, Schreckenberger M: German guidelines for brain tumour imaging by PET and SPECT using labelled amino acids. Nuklearmedizin 2011;50:167-73


Floeth FW, Stoffels G, Herdmann J, Eicker S, Galldiks N, Steiger HJ, Langen KJ. Prognostic Value of 18F-FDG PET in Monosegmental Stenosis and Myelopathy of the Cervical Spinal Cord. J Nucl Med. 2011 Aug 18. [Epub ahead of print] PubMed PMID: 21852356.

Langen KJ, Weckesser M, Floeth FW. Brain tumors: diagnostic impact of PET using radiolabelled amino acids. In M.A. Hayat (Editor): Tumors of the Central Nervous System, Springer Verlag


Cornelius JF, Langen KJ, Stoffels G, Hänggi D, Sabel M Steiger JH. PET imaging of meningioma in clinical practice– Review of literature and future directions, J Neurosurgery

Piroth MD, Pinkawa M, Holy R, Klotz J, Schaar S, Stoffels G, Coenen HH, Kaiser JH, Langen KJ, Eble MJ. Integrated-Boost-IMRT with FET-PET-adapted local dose escalation in glioblastomas - Results of a prospective Phase-II-study. Int J Radiat Oncol Biol Phys. 2011

Salber D, Stoffels G, Oros-Peusquens AM, Shah NJ, Reifenberger G, Hamacher K, Coenen HH, Langen KJ. Comparison of O-(2-[18F]fluoroethyl)-L-tyrosine and L-[3H]methionine uptake in cerebral hematomas. J Nucl Med 2010;51:790-797


Weckesser M, Langen KJ. Clinical Evaluation of Primary Brain Tumor: O-(2-[18 F]Fluorethyl)-L-Tyrosine Positron Emission Tomography. In M.A. Hayat (Editor): Methods of Cancer Diagnosis, Therapy, and Prognosis, 2010. Volume 8, Springer Verlag, 179-188


Becker JS, Zoriy M, Wu B, Matusch A, Salber D, Becker JS. Imaging Mass Spectrometry by Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in life sciences. Mass Spectrometry reviews, 2010;29:156-175

Becker JS, Matusch A, Palm C, Salber D, Morton KA, Becker JS: Bioimaging of metals in brain tissue by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and metallomics. Metallomics 2(2), 104-11, 2010

Becker JS, Niehren S, Matusch A, Wu B, Hsieh HF, Kumtabtin U, Hamester M, Plaschke-Schlütter A, Salber D. Scaling down the bioimaging of metals by laser microdissection inductively coupled plasma mass spectrometry (LMD-ICP-MS). International Journal of Mass Spectrometry 2010;294: 1-6

Piroth MD, Pinkawa M, Holy R, Klotz J, Nussen S, Stoffels G, Coenen HH, Kaiser JH, Langen KJ, Eble MJ. Prognostic Value of Early 18F-Fluoroethyltyrosine PET after Radiochemotherapy in Glioblastoma multiforme. Int J Radiat Oncol Biol Phys 2010, Epub 2010 Jun 21, DOI: 10.1016/j.ijrobp.2010.01.055

Floeth FW, Stoffels G, Herdmann J, Jansen P, Meyer W, Steiger HJ, Langen KJ. Regional impairment of 18F-FDG uptake in the cervical spinal cord below monosegmental cervical myelopathy. Eur Radiol Epub 2010 July 21, DOI: 10.1007/s00330-010-1877-S

Langen KJ, Weckesser M, Pauleit D, Steiger HJ. Nuklearmedizinische Diagnostik in der Neuroonkologie. Onkologische Welt 2010;1:169-171


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