Talk by Pedro Maldonado A, Ph.D.
Biomedical Neuroscience Institute, Center for Neuroscience of Memory, Programa de Fisiología y Biofísica, Faculty of Medicine, Universidad de Chile
- 25 Jun 2012 14:00
- 25 Jun 2012 15:00
"Synchronization Across Sensory Cortical Areas by Electrical Microstimulation is Sufficient for Behavioral Discrimination."
The temporal correlation hypothesis proposes that cortical neurons engage in synchronized activity, thus configuring a general mechanism to account for a range of cognitive processes from perceptual binding to consciousness. However, most studies supporting this hypothesis have only provided correlational, but not causal evidence.We used electrical microstimulation of the visual and somatosensory cortices of the rat in both hemispheres, to test whether distributed patterns of artificial synchrony evoke a coherent brain activation that rats can signal by pressing different levers. We demonstrated that rats can recognize artificial current patterns containing precise synchronization features, thus providing the first direct evidence that artificial synchronous activity can guide behavior.