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Selected Publications


  • Cichon N B, Denker M, Grün S, and Hanganu-Opatz I L (2014) Unsupervised classification of neocortical activity patterns in neonatal and pre-juvenile rodents. Front. Neural Circuits doi: 10.3389/fncir.2014.00050
  • Ito J, Roy S, Liu Y, Cao Y, Fletcher M, Lu L, Boughter J, Grün S, Heck D. (2014) Delta oscillations and gamma power in awake mouse whisker barrel cortex are linked to respiration. Nature Communications doi: 10.1038/ncomms4572


  • Torre, E, Picado-Muiño, D, Denker, M, Borgelt, C and Grün, S (2013) Statistical evaluation of synchronous spike patterns extracted by Frequent Item Set Mining. Front Comput Neurosci doi: 10.3389/fncom.2013.00132
  • Picado-Muiño D, Borgelt C, Berger D, Gerstein G, Grün S (2013) Finding neural assemblies with frequent item set mining. Front Neuroinform doi: 10.3389/fninf.2013.00009
  • Ito J, Maldonado P, Grün S (2013) Cross-frequency interaction of the eye-movement related LFP signals in V1 of freely viewing monkeys. Front Syst Neurosci 7:1 doi: 10.3389/fnsys.2013.00001
  • Pipa G, Grün S, van Vreeswijk C (2013) Impact of spike-train autostructure on probability distribution of joint-spike events Neural Comput. 25(5): 1123-1163 doi: 10.1162/NECO_a_00432 Epub 2013 Mar 7
  • Riehle A, Wirtssohn S, Grün S and Brochier T (2013) Mapping the spatio-temporal structure of motor cortical LFP and spiking activities during reach-to-grasp movements Front. Neural Circuits 7: 48 doi: 10.3389/fncir.2013.00048
  • Schultze-Kraft M, Diesmann M, Grün S, Helias M (2013) Noise Suppression and Surplus Synchrony by Coincidence Detection, PLoS Comput Biol 9(4): e1002904 doi:10.1371/journal.pcbi.1002904


  • Berger D, Pazienti A, Flores F J, Nawrot M, Maldonado PM, Grün S (2012) Viewing strategy of Cebus monkeys during free exploration of natural images. Brain Research 1434: 34-46 doi: 10.1016/j.brainres.2011.10.013
  • Borgelt C, Braune C, Kötter T, Grün S (2012) New algorithms for finding approximate frequent item sets. Soft Comput. 16(5): 903-917 doi: 10.1007/s00500-011-0776-2
  • Gerstein GL, Williams ER, Diesmann M, Grün S, Trengove C (2012) Detecting synfire chains in parallel spike data. J Neurosci Methods 206 (1): 54-64 doi: 10.1016/j.jneumeth.2012.02.003
  • Shimazaki H, Amari S, Brown E N, Grün S (2012) State-Space Analysis of Time-Varying Higher-Order Spike Correlation for Multiple Neural Spike Train Data. PLoS Comput Biol 8(3): e1002385 doi: 10.1371/journal.pcbi.1002385


  • Braune C, Borgelt C and Grün S (2011) Finding Ensembles of Neurons in Spike Trains by Non-linear Mapping and Statistical Testing Proc. 10th Int. Symposium on Intelligent Data Analysis (IDA 2011, Porto, Portugal) Springer-Verlag, Berlin, Germany 2011
  • Denker M, Roux S, Lindén H, Diesmann M, Riehle A, Grün S (2011) The local field potential reflects surplus spike synchrony Cereb. Cortex 21 (12): 2681-2695. doi: 10.1093/cercor/bhr040
  • Ito J, Maldonado P, Singer W, Grün S (2011) Saccade-related modulations of neuronal excitability support synchrony of visually elicited spikes Cereb. Cortex 21 (11): 2482-2497 doi: 10.1093/cercor/bhr020
  • Linden H, Tetzlaff T, Potjans T C, Pettersen K H, Grün S, Diesmann M, Einevoll G (2011) Modeling the Spatial Reach of the LFP. Neuron 72, 859–872 doi: 10.1016/j.neuron.2011.11.006



  • Grün S (2009) Data-driven significance estimation of precise spike correlation. J Neurophysiology, 101: 1126-1140 (invited review)
  • Grün S, Berger D, Borgelt C (2009) Identification of neurons participating in cell assemblies, IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP), 3493-3496
  • Kilavik B E, Roux S, Ponce-Alvarez A, Confais J, Grün S, Riehle A (2009) Long-term modifications in motor cortical dynamics induced by intensive practice J Neuroscience 29(40):12653 12663
  • Sharott A, Moll C, Engler G, Denker M, Grün S, Engel A (2009) Different subtypes of striatal neurons are selectively modulated by cortical oscillations. J Neuroscience, 29:4571-4585
  • Shimazaki H, Amari S, Brown E N, Grün S (2009) State-space analysis on time-varying correlations in parallel spike sequences, IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP), 3501-3504.


  • Grün S, Abeles M, and Diesmann M. (2008) Impact of higher-order correlations on coincidence distributions of massively parallel data. Lecture Notes in Computer Science, 'Dynamic Brain - from Neural Spikes to Behaviors' , vol 5286, 96-114 DOI:10.1007/978-3-540-88853-6 preprint
  • Maldonado P, Babul C, Singer W, Rodriguez E, Berger D and Grün S. (2008) Synchronization of neuronal responses in primary visual cortex of monkeys viewing natural images. J Neurophysiol, 100: 1523 1532.
  • Pazienti A, Maldonado P, Diesmann M, Grün S (2008) Effectiveness of systematic spike dithering depends on the precision of cortical synchronization Brain Research, 1225: 39-46.
  • Schrader S, Grün S, Diesmann M, Gerstein G. (2008) Detecting synfire chain activity using massively parallel spike train recording. J Neurophysiol. 100(4):2165-2176
  • Staude B, Rotter S, and Grün S (2008) Can spike coordination be differentiated from rate covariation? Neural Computation 20, 1973 1999. preprint


  • Berger D, Warren D, Normann R, Arieli A, and Grün S (2007) Spatially organized spike correlation in cat visual cortex. Neurocomputing 70: 2112-2116
  • Denker M, Roux S, Timme M, Riehle A, Grün S (2007) Phase synchonization between LFP and spiking activity in motor cortex during movement preparation. Neurocomputing 70: 2096-2101
  • Nawrot M P, Boucsein C, Rodriguez-Molina V, Aertsen A, Grün S and Rotter S (2007) Serial interval statistics of spontaneous activity in cortical neurons Neurocomputing 70: 1717-1722
  • Pazienti A, Diesmann M, and Grün S. (2007) Bounds of the ability to destroy precise coincidences by spike dithering Lecture Notes in Computer Science 4729, pp. 428 437
  • Pipa G, Riehle A, and Grün S (2007) Validation of task-related excess of spike coincidences based on NeuroXidence Neurocomputing 70: 2064-2068


  • Pazienti A and Grün S (2006) Robustness of the significance of spike correlation with respect to sorting errors. Journal of Computational Neuroscience 21:329-342.
  • Czanner G, Grün S, and Iyengar S (2005) Theory of the snowflake plot and its relations to higher-order analysis methods. Neural Computation 17(7): 1456-1479.
  • Pipa G, Diesmann M, and Grün S (2003) Significance of joint-spike events based on trial-shuffling by efficient combinatorial methods Complexity 8(4): 79-86
  • Pipa G and Grün S (2003) Non-parametric significance estimation of joint-spike events by shuffling and resampling Neurocomputing 52-54: 31-37
  • Schneider G and Grün S (2003) Analysis of higher-order correlations in multiple parallel processes Neurocomputing 52-54: 771-777
  • Grün S, Riehle A, and Diesmann M (2003) Effect of cross-trial nonstationarity on joint-spike events. Biological Cybernetics 88(5): 335-351.
  • Grün S, Riehle A, Aertsen A, and Diesmann M (2003) Temporal scales of cortical interactions. Nova Acta Leopoldina 88(332): 1-18.
  • Gal V, Grün S, and Tetzlaff R (2003) Analysis of multidimensional neural activity via CNN-UM. International Journal Neural Systems 13(6): 479-487.
  • Grün S, Diesmann M, and Aertsen A (2002) `Unitary Events' in multiple single-neuron activity. II. Non-Stationary data. Neural Computation 14(1): 81-119.
  • Grün S, Diesmann M, and Aertsen A (2002) `Unitary Events' in multiple single-neuron activity. I. Detection and significance. Neural Computation 14(1): 43-80.
  • Gal V, Grün S, and Tetzlaff R (2002) Analyzing multidimensional neural activity via CNN-UM. In Tetzlaff R, editor, Proc 7th IEEE Intern Workshop on Cellular Neural Networks and their Applications, pages 243-250. World Scientific, Singapore.
  • Aertsen A, Diesmann M, Gewaltig M-O, Grün S, and Rotter S (2001) Neural dynamics in cortical networks -- precision of joint-spiking events. In Bock G and Goode J, editors, Complexity in biological information processing, volume 239 of Novartis Foundation Symposium 2001, pages 193-207. Wiley, Chichester.
  • Grün S, Wagner H, Carr C, and Aertsen A (2001) Binaural interaction in the nucleus laminaris of the barn owl: A quantitative model. Research Report BrainWorks 1991-01, Neurobiology & Biophysics, ISSN 1615-2042, Inst. Biology 3, Albert-Ludwigs Univ, Freiburg, Germany.
  • Riehle A, Grammont F, Diesmann M, and Grün S (2000) Dynamical changes and temporal precision of synchronized spiking activity in monkey motor cortex during movement preparation. Journal of Physiol (Paris) 94(5-6): 569-582.
  • Grün S, Diesmann M, Grammont F, Riehle A, and Aertsen A (1999) Detecting unitary events without discretization of time. Journal of Neuroscience Methods 94:67-79.
  • Grün S and Rotter S (1999) Concepts of neuronal cooperativity in the cortex. In Elsner N and Eysel U, editors, From Molecular Neurobiology to Clinical Neuroscience, pages 359-363, Thieme Verlag, Stuttgart.
  • Riehle A, Grün S, Diesmann S, and Aertsen S (1997) Spike synchronization and rate modulation differentially involved in motor cortical function. Science 278: 1950-1953.
  • Riehle A, Grün S, Aertsen A, and Requin J (1996) Signatures of dynamic cell assemblies in monkey motor cortex. In von der Malsburg C, von Seelen W, Vorbrüggen J C, and Sendhoff B, editors. Artificial Neural Networks - ICANN '96, pages 673-678, Berlin, Springer.
  • Martignon L, von Hasseln H, Grün S, Aertsen S, and Palm G (1995) Detecting higher-order interactions among the spiking events in a group of neurons. Biological Cybernetics 73: 69-81


Grün S. and Rotter S. (eds.) Analysis of Parallel Spike Trains (2010) Springer Series in Computational Neuroscience, Volume 7, Springer New York, DOI: 10.1007/978-1-4419-5675-0
  • Grün S (1996) Unitary Joint-Events in Multiple-Neuron Spiking Activity: Detection, Significance, and Interpretation. Reihe Physik, Band 60. Verlag Harri Deutsch, Thun, Frankfurt/Main, ISBN 3-8171-1506-7.