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Articles in peer reviewed journals

    2018
    • Schartmann E., Schemmert S., Niemietz N., Honold D., Ziehm T., Tusche M., Elfgen A., Gering I., Brener O., Shah NJ., Langen KJ., Kutzsche J., Willbold D., Willuweit A. (2018) In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer's Disease. J Alzheimers Dis. 64(3):859-873. doi: 10.3233/JAD-180165
    • Hupert M., Elfgen A., Schartmann E., Schemmert S., Buscher B., Kutzsche J., Willbold D., Santiago-Schübel B. (2018) Development and validation of an UHPLC-ESI-QTOF-MS method for quantification of the highly hydrophilic amyloid-β oligomer eliminating all-D-enantiomeric peptide RD2 in mouse plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 1073:123-129. doi: 10.1016/j.jchromb.2017.12.009
    2017
    • van Groen T., Schemmert S., Brener O., Gremer L., Ziehm T., Tusche M., Nagel-Steger L., Kadish I., Schartmann E., Elfgen A., Jürgens D., Willuweit A., Kutzsche J., Willbold D. (2017) The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology. Sci Rep. 7(1):16275. doi: 10.1038/s41598-017-16565-1
    • Elfgen A., Santiago-Schübel B., Gremer L., Kutzsche J., Willbold D. (2017) Surprisingly high stability of the Aβ oligomer eliminating all-d-enantiomeric peptide D3 in media simulating the route of orally administered drugs. Eur J Pharm Sci. 107:203-207. doi: 10.1016/j.ejps.2017.07.015
    • Klein AN., Ziehm T., van Groen T., Kadish I., Elfgen A., Tusche M., Thomaier M., Reiss K., Brener O., Gremer L., Kutzsche J., Willbold D. (2017) Optimization of d-Peptides for Aβ Monomer Binding Specificity Enhances Their Potential to Eliminate Toxic Aβ Oligomers. ACS Chem Neurosci. 8(9):1889-1900. doi: 10.1021/acschemneuro.7b00045
    2016
    • Rudolph S., Klein AN., Tusche M., Schlosser C., Elfgen A., Brener O., Teunissen C., Gremer L., Funke SA., Kutzsche J., Willbold D. (2016) Correction: Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity. PLoS One. 11(7):e0159470. doi: 10.1371/journal.pone.0159470
    • Rudolph S., Klein AN., Tusche M., Schlosser C., Elfgen A., Brener O., Teunissen C., Gremer L., Funke SA., Kutzsche J., Willbold D. (2016) Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity. PLoS One. 11(2):e0147470. doi: 10.1371/journal.pone.0147470
    2012
    • Slowik A., Merres J., Elfgen A., Jansen S., Mohr F., Wruck CJ., Pufe T., Brandenburg LO. (2012) Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells. Mol Neurodegener. 7:55. doi: 10.1186/1750-1326-7-55

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