Dr. Thomas Gensch


List of Publications (pdf)

Topic of research: fluorescence imaging (two-photon, lifetime)
single molecule spectroscopy
biological photoreceptors

Curriculum Vitae:

19.07.1966 born in Berlin, Germany
1985 Abitur, special school for mathematics and physics "Heinrich-Hertz" in Berlin
09/1987 - 11/1992 Study of Physics at the Humboldt-University in Berlin
Title of Diploma thesis: Investigations of the photosensitized singlet molecular oxygen generation in aqueous detergent solutions.
11/1992 - 01/1993 research at the Dept. of Physics at the Humboldt-University in Berlin in the laboratory Prof. Dr. B. Röder
02/1993 - 12/1996 PhD work at the Max-Planck-Institute for Radiation Chemistry (now Bioanorganic Chemistry) in Mülheim, laboratory of Prof. Dr. Silvia Braslavsky and Dept. of Biology (Institute for Physical Biology), Heinrich-Heine-University Düsseldorf (Prof. Dr. Büldt)
Title of PhD thesis: Time-resolved laser-induced optoacoustic spectroscopy on dyes, biological photoreceptors and photosynthetic reaction centers in solution.
12/1996 - 07/1997 Post-Doc at the Max-Planck-Institute for Radiation Chemistry (now Bioanorganic Chemistry) in Mülheim, laboratory of Prof. Dr. Silvia Braslavsky
08/1997 - 07/1999 Post-Doc at the Dept. of Chemistry, Catholic University Leuven, Belgium, in the laboratory of Prof. Dr. Frans C. De Schryver
04/1998 Casimir-Ziegler Award of the Royal Dutch Academy of Science and the Nordrhein-Westfälische Academy of Science
08/1999 - 07/2000 Post-Doc at the Swammerdam Institute of Life Sciences at the University of Amsterdam in the laboratory of Prof. Dr. Klaas Hellingwerf
since 08/2000 Senior scientist at the Institute of Structural Biology and Biophysics 1 (former Institute of Biological Information Processing 1) at the Research Center Jülich
since 05/2001 in the board of the registered association "Kleine Füchse (Little Foxes)" managing childcare facilities for children from 1 to 12 years
09/2003 Co-organizer of the biyearly Round Table Discussions on the "Spectroscopy of Biological Photoreceptors" (Ringberg-Meeting) by the Max-Planck-Society in 2003 in Frauenchiemsee.
01/2006 Co-organizer of the Xth School of the Italian Biophysics Society in Venice/Italy with the programme "Time resolved spectroscopic methods in biophysics"
06/2006 Co-editor of a Special Issue of Photochemical and Photobiolocal Sciences "Proton Transfer in Biological Systems".

selected publications:

Gensch T., Braslavsky, S. E.
'Volume changes related to triplet formation of a water-soluble porphyrin. A light-induced optoacoustic spectroscopy (LIOAS) study.'
Journal of Physical Chemistry B 101 (1997) 101-108

Gensch T., Viappiani C., and Braslavsky S.E.
'Photoacoustic spectroscopy in solution, Applications.'
in Encyclopedia of Spectroscopy and Spectrometry Academic Press Ltd. London UK (1999)

Gensch T., Hofkens J., Hermann A., Tsuda K., Verheijen W., Vosch T., Christ T., Basche T., Müllen K., De Schryver F. C.
'Fluorescence detection from single dendrimers with multiple chromophores.'
Angewandte Chemie International Edition English 38 (1999) 3752-3756

Tsuda K., Dol G., Gensch T., Hofkens J., Latterini L., Weener J.W., Meijer E.W., and De Schryver F.C.
'Microscopy, Microspectroscopy and Optical Fluorescence from Azobenzene Functionalized Poly(propylene imine) Dendrimers in Self-Assembled Supramolecular Structures.'
Journal of the American Chemical Society 122 (2000) 3445-3452

Hofkens J., Maus M., Gensch T., Vosch T., Cotlet M., Köhn F., Herrmann A., Müllen K., De Schryver F.C.
'Probing photophysical processes in individual multichromophoric dendrimers by single molecule spectroscopy.'
Journal of the American Chemical Society 122 (2000) 9278-9288

van Thor J.J., Gensch T., Hellingwerf K.J., L. Johnson L.
'Phototransformation of the wild-type A. Victoria Green Fluorescent Protein with UV- and Visible light leads to decarboxylation of Glutamate-222.'
Nature Structural Biology 9 (2002) 37-41

Hendriks J., Gensch T., Hviid L., van der Horst M.A., Hellingwerf K.J., and van Thor J.J.
'Transient exposure of hydrophobic surface in the photoactive yellow protein monitored with Nile Red.'
Biophysical Journal 82 (2002) 1632-1643

Hellingwerf K.J., Hendriks J., Gensch T.
'The yellow lab: Will it bring us where we want to go?. '
Journal of Physical Chemistry A 107 (2003) 1082-1094

Gensch T., Viappiani, C.
'Tme-resolved photothermal methods: accessing time-resolved thermodynamics of photoinduced processes in chemistry and biology. '
Photochemical and Photobiological Sciences 2 (2003)699-721

Kaneko H., Putzier I., Frings S., Kaupp U.B., and Gensch T.
'Chloride accumulation in mammalian olfactory sensory neurons. '
Journal of Neuroscience 24 (2004) 7931-7938

Gensch T., Hendriks J., and Hellingwerf K.J.
'Tryptophan fluorescence monitors structural changes accompanying signaling state formation on the photocycle of photoactive yellow protein. '
Photochemical and Photobiological Sciences 3 (2004) 531-536

Polverini, E., Cugini, G., Annoni, F., Abbruzzetti, S., Viappiani, C., and Gensch T.
'Molten Globule Formation in Apomyoglobin Monitored by the Fluorescent Probe Nile Red. '
Biochemistry 45 (2006) 5111-5121



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