Prof. Dr. U. Benjamin Kaupp


 Prof.  Dr. U. Benjamin Kaupp Teaching

Publications (pdf)

Topic of research: sensory physiology, ion channels, chemotaxis

Curriculum Vitae:

1968-1971 Study of Chemistry and Psychology (University Tübingen)
1971-1974 Study of Chemistry and Psychology (Technical University Berlin)
1974-1979 PhD work at the Max-Vollmer-Insitute, Technical University Berlin (Prof. Dr. W. Junge)
Title of PhD thesis: Blitzlichtphotometrische Untersuchungen der schnellen, licht-induzierten Kalziumfreisetzung in isolierten Rindersehstäbchen.
1981 Post-doctoral fellow at the Department of Physiology and Biophysics; SUNY Stony Brook, USA (Prof. Dr. J.E. Brown)
1983 Habilitation at the University of Osnabrück; venia legendi for Biophysics
1987 Feodor-Lynen-Award of the Alexander-v.-Humboldt-Society at the Department of Medical Chemistry, Faculty of Medicine, University of Kyoto, Japan (Prof. S. Numa)
since 1988 Director of the Institut für Biologische Informationsverarbeitung 1 (Forschungszentrum Jülich) and Professor of Biophysical Chemistry (University of Cologne)
1994 Alcon Research Award
1995-2005 Member of the Scientific Advisory Board of the Institute for Science and Ethics, University Bonn
since 1996 Curator of the Boehringer Ingelheim Fonds
since 1997 Member of the Scientific Advisory Board, Cohn Minerva Center, Weizmann Institute, Israel
1997-2003 Coordinator of the nation-wide Special Research Programme "Molecular Sensory Physiology" of the Deutsche Forschungsgemeinschaft
since 1997 Chairman of the Advisory Board of the "Center for Molecular Neurobiology" University Hospital, Hamburg
since 1999 Member of the Advisory Board of the Max-Planck-Institut für Hirnforschung, Frankfurt
since 1999 Member of the Advisory Board of the Max-Planck-Institut für experimentelle Medizin, Göttingen
2001 - 2002 Vice-Chair of the Wiss. Techn. Rat and Hauptkommission, FZ Jülich
since 2003 Rapporteur of the evaluation committee of Max-Planck-Institutes
since 2003 Member of the Minerva Stipend-Committee
since 2003 Chairman of the Scientific Advisory Board of the Wilhelm-Kühne-Minerva Center in Jerusalem, Israel
2004 Vice-Chairman of the Gordon Conference "Ligand Recognition & Molecular Gating"
since 2005 Member of the Deutsche Akademie der Naturforscher Leopoldina
since 2006 Member of the " Senate Committee for Collaborative Research Centres" of the German Research Foundation (DFG)
2006 Chairman of the Gordon Conference "Ligand Recognition & Molecular Gating"

selected publications:

Cook N.J., Hanke W., Kaupp U.B.
'Identification, purification, and functional reconstitution of the cyclic GMP-dependent channel from rod photoreceptors.'
Proceedings of the National Academy Science USA 84 (1987) 585-589

Kaupp U.B., Niidome T., Tanabe T., Terada S., Bönigk W., Stühmer W., Cook N.J., Kagawa K., Matsuo H., Hirose T., Miyata T., Numa S.
'Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel.'
Nature 342 (1989) 762-766

Weyand I., Godde M., Frings S., Weiner J., Müller F., Altenhofen W., Hatt H., Kaupp U.B.
'Cloning and functional expression of a cyclic-nucleotide-gated channel from mammalian sperm.'
Nature 368 (1994) 859-863

Körschen H.G., Illing M., Seifert R., Williams A., Gotzes S., Colville C., Müller, F., Dosé A., Godde M., Molday L., Kaupp U.B., Molday R.S.
'A 240K protein with a bipartite structure represents the complete β-subunit of the cyclic nucleotide-gated channel from rod photoreceptor.'
Neuron 15 (1995) 627-636

Gauss R., Seifert R., Kaupp U.B.
'Molecular identification of a hyperpolarization-activated channel (Ih) in sea urchin sperm.'
Nature 393 (1998) 583-587

Körschen H.G., Beyermann M., Müller F., Heck M., Vantler M., Koch K.-W., Kellner R., Wolfrum U., Bode C., Hofmann K.P., Kaupp U.B.
'Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors.'
Nature 400 (1999) 761-766

Stevens, D.R., Seifert, R., Bufe, B., Müller, F., Kremmer, E., Gauss, R., Meyerhof, W., Kaupp, U.B., Lindemann, B.
'Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.'
Nature 413 (2001) 631-635

Weitz D., Ficek N., Kremmer E., Bauer P.J., Kaupp U.B.
'Subunit stoichiometry of the CNG channel of rod photoreceptors.'
Neuron 36 (2002) 881-889

Kaupp U.B., Solzin J., Hildebrand E., Brown, J.E., Helbig A., Hagen V., Beyermann M., Pampaloni F., Weyand I.
'The signal flow and motor response controling chemotaxis of sea urchin sperm.'
Nature Cell Biology 5 (2003) 109-117

Böhmer M., Van Q., Weyand I., Hagen V., Beyermann M., Matsumoto M., Hoshi M., Hildebrand E., Kaupp U.B.
'Ca2+ spikes in the flagellum control chemotactic behaviour of sperm.'
EMBO Journal 24 (2005) 2741-2752

Strünker T., Weyand I., Bönigk W., Van Q., Loogen A., Brown J.E., Kashikar N., Hagen V., Krause E., Kaupp U.B.
'K+-selective cGMP-gated ion channel controls chemosensation of sperm.'
Nature Cell Biology 8 (2006) 1149-1154



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