Welcome to ISB-3: Structural Biochemistry
The research areas of ISB-3 comprise the investigation of precise three-dimensional structures of biologically and medically relevant macromolecules as well as their interactions with other proteins and small ligands. Research is focused on proteins that are involved in diseases like AIDS, SARS and neurodegenerative disorders to study the molecular basis of these diseases and to investigate novel approaches to therapy. Furthermore, ultra-sensitive assays potentially suitable for early and non-invasive diagnosis of neurodegenerative disorders like Alzheimer’s disease and prion diseases are developed. For these research purposes molecular biology as well as several biophysical techniques e.g. liquid and solid state NMR and fluorescence correlation spectroscopy are developed and applied in addition to X-ray crystallography (in cooperation with ISB-2). Moreover, computational biology approaches in the fields of structural biology are performed.
| Contact | Director |
Institute of Structural Biology and Biophysics (ISB) | Prof. Dieter Willbold |
last changed 19.08.2009 | | Print