Medical imaging group
Head:  Dr. rer. nat. Simone Weber


Methodology for high resolution positron emission tomography (µPET) and combination of µPET with anatomical imaging modalities


PET principle

 

What is µPET?

 

Positron Emission Tomography is a non-invasive technique for studying in vivo tracer pharmacokinetics and metabolism. High resolution PET (µPET) for small animals is used e.g. for receptor studies in brain research or for the imaging of gene expression in living animals. µPET allows to examine the tracer kinetics in a single animal. While human PET systems have a spatial resolution of 5-7mm, high resolution PET needs a spatial resolution of <2mm and a high sensitivity.

 

Research topics

  Reconstruction and Correction Methods

 Standardization of Performance Measurements

 Monte Carlo Simulation for Medical Imaging Instrumentation and Methodology

Recent Presentations
  • IEEE Nuclear Science Symposium & Medical Imaging Conference, San Diego, 29.10.-04.11.2006 - Dynamic List-Mode reconstruction of PET data based on the ML-EM algorithm  (poster, pdf)
  • IEEE Nuclear Science Symposium & Medical Imaging Conference, San Diego, 29.10.-04.11.2006 - Parallel List-Mode reconstruction and calculation of the system matrix for the high-resolution ClearPET Neuro
  • Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaft für Biomedizinische Technik, 06.-09.09.2006, Zürich - Characterisation and compensation strategies for the small animal scanner ClearPET Neuro and their effects with regard to the slice by slice variation of the spatial resolution
  • ESMI, 1st International Conference of the European Society for Molecular Imaging, 17.-19.05.2006, Paris - Geometric sensitivity of the ClearPET Neuro
  • ESMI, 1st International Conference of the European Society for Molecular Imaging, 17.-19.05.2006, Paris - List-mode image reconstruciton for the ClearPET Neuro
  • EuroMedIm2006, 1st European Conference on Molecular Imaging Technology, 9.-12.5.2006, Marseille - Geometric sensitivity of ClearPET Neuro  (poster, pdf)

    •  Previous presentations

Interesting Links

 Let's play PET - UCLA's introduction into PET

 Molecular Imaging Central - more about Molecular Imaging

 Webcast on New Molecular Imaging Systems and Technologies  - Webcast of Dr. Simon Cherry's lecture at the MIPS/GE Medical Systems/Amersham Health Molecular Imaging Seminar Series.

emil_logo - Network of Excellence of the EU Sixth Framework Programme

 ClearPET-Sites

Staff
Dissertations
  • Maryam Khodaverdi, "Designstudie eines µCT-Zusatzes für einen hochauflösenden Positronen-Emissions-Tomographen", Bergische Universität Wuppertal (2003) (in German)
Theses
  • Christian Unger, "Untersuchungen zur Bestimmung des räumlichen Auflösungsvermögens für hochauflösende PET", RheinAhrCampus Remagen, Fachhochschule Koblenz (2005) (in German)
  • Daniela Christ, "Untersuchung von LuYAP als Szintillationskristall im Vergleich zu LSO- und BGO-Kristallen für den Einsatz in der hochauflösenden Positronen-Emissions-Tomographie", Westsächsische Hochschule Zwickau (2002) (in German)
  • Axel Blume, "Optimierung der Lichtausbeute und Energieauflösung von LSO-Szintillationskristallen zur Anwendung in hochauflösenden Positronen-Emissions-Tomographen", Fachhochschule Lübeck (2000) (in German)
Reports
Cooperations

IME - Institute of Medicine, Forschungszentrum Jülich

INC - Institute of Nuclear Chemistry, Forschungszentrum Jülich

 Crystal Clear Collaboration

 EMIL - European Molecular Imaging Laboratories, Network of Excellence of the EU Sixth Framework Programme .

  FH Koblenz, RheinAhrCampus Remagen




last change 30.01.2007 | | Print