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Institute of Neuroscience and Medicine

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Sam Vickery

M.Sc. Sam Vickery

Ph.D. student

Methodological topics:

• Voxel Based Morphometry (VBM)
• Unsupervised clustering methods (Non-negative matrix Factorization)
• Structural MRI in humans and primates

My research focuses on the structural configuration of the chimpanzee brain. A key aspect in understanding structural patterns within the chimpanzee brain is to identify regions that co-vary across subjects in a consistent way, which may indicate basic neural networks. To this effect, Voxel Based Morphometry (VBM) is used to extract local grey matter densities for the analysis of the structural covariance. Then Non-Negative Matrix Factorization (NNMF) is applied, which allows for a sparse representation of brain structure by co-varying regions.
The intention is to utilize this factorization to devise a structural parcellation of the chimpanzee brain. A key question here is which minimum number of parcels best describe common variance over individual brains.
The overarching goal is to conduct interspecies comparisons to further our understanding of the brain from an evolutionary stand point.


Institute of Neuroscience and Medicine (INM-7)
52425 Jülich


Phone: +49 2461 61-85333
Fax: +49 2461 61-1880