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New Light Shed on "Chameleon Proteins"

Neutrons reveal power play in myelin basic protein

Jülich, 21 May 2014 – Intrinsically disordered proteins (IDP) are the quick-change artists of protein molecules. In aqueous solution, they have no clearly defined structure and can bend with a high degree of flexibility. Jülich neutron researchers have circumvented the shortcomings of conventional methods by using a novel approach to obtain new insights into these chameleon-like proteins. Their findings revolutionize prevailing assumptions about the biomolecular functioning of this key element of the central nervous system and have been published in the journal JACS.

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