Navigation and service

Advertising division: ICS-6 - Structural Biochemistry
Reference number: 2019-413


The function of each cell and organism depends crucially on the dynamic interactions between biological macromolecules and their correct three-dimension structure. Faulty interactions and misfolded structeres ultimately lead to disease and aging. The goal of ICS-6 is to understand these interactions and to determine the three-dimensional structures of the protein complexes involved in crucial cellular processes as far as possible at atomic resolution. In addition, the department is developing novel methods for the early detection and therapy of neurodegenerative diseases with a strong Focus on Alzheimer´s dementia.

The laboratory of "Cellular and systemic propagation of protein aggregation in neurodegenerative diseases" is focused on understanding how disease-associated proteins misfold, spread, and damage the nerve system. The main focus is here on Parkinson´s disease, Alzheimer´s disease, and amyotrophic lateral sclerosis.

Verstärken Sie diesen Bereich zum nächstmöglichen Zeitpunkt als

Research technician or life scientist for Parkinson`s disease research

Your Job:

  • perform behavioral experiments in mice (pole-test, novel object recognition test, rotarod-test, etc.)
  • scoring of mice by weight and based on neurological criteria
  • preparation of tissue sections
  • immunhistochemical and immunfluorescence analysis of tissue sections
  • preparation of solutions, buffers and test series
  • carrying out general lab work, care and maintenance of laboratory equipment as well as the organization of maintenance and repair work

Your Profile:

  • Completed training as a technical assistant (MTA/BTA/CTA/PTA) with good results, or a university degree as bachelor of science or engineering in one of the fields of study discribed or comparable education
  • FELASA-B certification
  • Several years of experience in behavioral testing and histology
  • Extensive experience with rodent neuroscience/neurobiology and mouse models of neurodegenerative diseases
  • Very good experience with culturing cell lines and primary neurons and with handling nucleic acids (PCR/qRT-PCR) and proteins (SDS-PAGE/Western Blot and Elisa)
  • Good German and English skills in word and writing
  • Good computer and software skills (Word, Excel, Fiji, ImageJ)
  • Very strong ability to cooperate
  • A high sense of responsibility
  • Very careful working style as well as a structured and systematic way of working

Our Offer:

  • A varied and challenging field of work
  • An excellent technical infrastructure
  • Exciting working environment on an attractive research campus with excellent infrastructure, located between the cities of Cologne, Düsseldorf, and Aachen
  • International and interdisciplinary working atmosphere
  • A comprehensive further training programme
  • Flexible working hours and various opportunities to reconcile work and private life
  • Limited for 2 years
  • Full-time position with the option of slightly reduced working hours
  • Salary and social benefits in conformity with the provisions of the Collective Agreement for the Civil Service (TVöD)

Forschungszentrum Jülich aims to employ more women in this area and therefore particularly welcomes applications from women.

We also welcome applications from disabled persons.