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!POSTPONED! Theory Seminar & Webinar: Filamentous Active Matter: Band Formation, Bending, Buckling, and Defects

Gerrit A. Vliegenthart, Forschungszentrum Jülich, IBI-5 &IAS-2

04.06.2020 11:00 Uhr
Room 2001, Building 04.16 and by remote access

This seminar has been postponed until further notice. Thank you for your understanding.


In the complex environment of biological cells, molecular motors coupled to cytoskeletal filaments are important for the cell's structure, integrity, mobility as well as for intracellular transport. In vitro, using purified model systems, it has been found that the same motor proteins drive the self-organisation of concentrated suspensions of cytoskeletal filaments into so-called active nematics.

We perform computer simulations of polar filaments and molecular motors linking microscopic interactions and activity to self-organisation and dynamics from the filament level up to the mesoscopic domain level. Dynamic filament crosslinking and sliding, and excluded-volume interactions promote formation of bundles at small densities, and of active polar nematics at high densities. A buckling-type instability sets the size of polar domains and the density of topological defects.

We predict a universal scaling of the active diffusion coefficient and the domain size with activity, and its dependence on parameters like motor concentration and filament persistence length.