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BioSoft Colloquium:

Biophysics of protein aggregation

Tuomas Knowles

Biophysics & Biophysical Chemistry,
Department of Chemistry, University of Cambridge, UK


begin
27 May 2021 11:00
venue
Remote access

Join us at: www.fz-juelich.de/ibi/TPLMSem

Abstract:

This talk describes our efforts to elucidate the molecular mechanisms of protein aggregation as well as the kinetics of this process and how these features connect to the biological roles that these structures can have in both health and disease. A particular focus will be on the development and use of physical tools and concepts, including reaction kinetics, to discover molecular assembly pathways in amyloid formation.

Moreover we will discuss the development of new microfluidics approaches to study heterogeneous protein self-assembly and their application to explore the molecular determinants of amyloid formation from peptides and proteins.

Theoretical Physics Copyright: Tuomas Knowles, Department of Chemistry, University of Cambridge, UK

Contact

Dr. Dmitry Fedosov
Phone: +49 2461 61-2972
Fax: +49 2461 61-3180
email: d.fedosov@fz-juelich.de