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Labs! Visit on Protein Structure Determination by X-Ray Crystallography

25 Mar 2020 09:15
25 Mar 2020 10:45
building 05.8v, room 3016b

Renu Batra-Safferling, Oliver Weiergräber
(Structural Biochemistry)

The most widely used method for the determination of high-resolution structures of biological samples is X-ray crystallography. In this lab visit, you will get an idea of the workflow in a protein crystallography lab, i.e., how a protein structure model at atomic resolution is obtained from purified protein in solution. The equipment includes Tecan robot (for high throughput automated screening of crystal growth), a digital doc- umentation system (for evaluation and recording of the optimized crystals), and an in-house rotating anode generator (for single crystal X-ray diffraction experiments). You will be able to see finalized 3D protein models using the computer infrastructure equipped with crystallographic software.

Online registration is mandatory and all places are subject to availability; you will receive an email confirmation once your place on the seminar is reserved.

This Labs! event is offered in collaboration with the IFF Spring School.