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Neuroanatomy and It’s impact on Structural and Functional Imaging (In Honor of Karl Zilles)

30 May 2021
04 Jun 2021

Name of Organizers:

Kevin Weiner
University of California, Berkeley
Berkeley, CA

Hiromasa Takemura
Center for Information and Neural Networks (CiNet)
National Institute of Information and Communications Technology
Osaka, Japan

Nicola Palomero-Gallagher
Institute of Neuroscience and Medicine (INM-1)
Research Centre Jülich
Jülich, Germany

The course will provide an introduction and critical overview of classical and modern approaches for studying the anatomy of the brain using neuroimaging techniques. It is aimed at a multidisciplinary audience, and will provide an introduction to brain macroscopy, gross anatomical landmarks and its intersubject variability, the microstructural organization of the cortical areas, spatial organization of white matter tracts, how different neuroanatomical features of the brain contribute to the representation of cognitive functions, as well as brain development as assessed by novel and timely MR techniques such as quantitative MRI (qMRI) and lipidomics. All these aspects come together in an atlas, where their relationship can be studied. Neuroimaging methods will be discussed with respect to their advantages, disadvantages, and potential pitfalls as it concerns anatomy. The relevance of anatomical knowledge for the interpretation of structural and/or functional imaging data will be made explicit. The course will cover talks introducing anatomical concepts and developmental aspects, also showing how MRI contributes; discussing organizational principles of the brain’s microstructure (cyto-, receptor- and myeloarchitecture), and thus, critically reflecting the perspectives and limits of MR imaging with respect to these aspects of brain organization; and elucidating the relationship between microstructure and brain function, and providing an overview of some widely distributed neuroimaging tools in this field. Participants of the course will thus be able to interpret neuroimaging findings within the underlying anatomical framework of the brain and to critically evaluate advantages and limitations of different neuroanatomical and neuroimaging methods. Therefore, this educational course will provide important perspectives on how to bridge anatomical and neuroimaging methods to understand structural and functional organizations of human brains.