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PhD Position – Computational investigation of ion channels and transporters
Using a combination of molecular simulations, patch-clamp electrophysiology, and molecular biology, the Computational Neurophysiology group of Jan-Philipp Machtens at the Institute of Biological Information Processing 1 investigate the structure-dynamics-function relationships of physiologically and clinically important membrane proteins. Furthermore, we study pathologic alterations of these proteins towards novel strategies to pharmacologically correct protein and cell function under disease conditions. The PhD project will focus on permeation and selectivity mechanisms in ion channels, mechanisms of ligand and voltage activation, or functional principles of thermodynamically coupled transporters.
Last Modified: 31.01.2023