Bacterial Protein Secretion

About

Our focus: Investigation of mechanistic aspects of protein secretion in bacteria and its application for the secretory production of heterologous proteins.

Transport of proteins across biological membranes is a crucial process in all kingdoms of life. In bacteria, the transport of proteins out of the cytosol is mediated mainly by two mechanistically different export pathways, the general secretion (Sec) pathway and the twin-arginine-translocation (Tat) pathway. Current research of our group focusses on the investigation of various mechanistic aspects of Tat-dependent protein translocation and the optimization of selected Gram-positive bacteria as host organisms for the secretory production of biotechnologically and pharmaceutically relevant heterologous proteins.

Contact

Prof. Dr. Roland Freudl

IBG-1

Building 15.4 / Room 130

+49 2461/61-3472

E-Mail

Members

Prof. Dr. Roland Freudl

Head of Bacterial Protein Secretion

  • ibg
  • ibg-1
Building 15.4 /
Room 130
+49 2461/61-3472
E-Mail

Felix Küttner

Ph.D. student

  • ibg
  • ibg-1
Building 15.4 /
Room 222
+49 2461/61-6043
E-Mail

Astrid Bida

Technical staff

  • ibg
  • ibg-1
Building 15.4 /
Room 225
+49 2461/61-5827
E-Mail

Doris Dohmen-Olma

Technical staff

  • ibg
  • ibg-1
Building 15.4 /
Room 224
+49 2461/61-5827
E-Mail

Last Modified: 13.11.2022