Institute of Neuroscience and Medicine
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Institute of Neuroscience and Medicine
To reconstruct the nerve fiber architecture from the images generated in the 3D-PLI measurement, various methods of signal and image processing are employed. The methods are validated by analytical methods and numerical simulations.
To process and handle the measurement data of up to 1 Terabyte per brain section, the resources of the Jülich Supercomputing Centre (JSC) are exploited. The developed software utilizes either a large number of processors or graphic cards.
Computational Workflow: This workflow describes the different steps, computing platform and output images of 3D-PLI.
Copyright: Forschungszentrum Jülich GmbH
The parameter maps shown in the figure above (transmittance, direction, retardation, inclination) are extracted from the measured raw images by employing different methods of signal and image processing.
Copyright: Top left/Middle right: adapted from Schmitz et al., Frontiers (2018); Rest: Schmitz/Schober, Forschungszentrum Jülich GmbH