(Selection)
Üffing, A., Weiergräber, O.H., Schwarten, M., Hoffmann, S., and Willbold, D. (2024). GABARAP interacts with EGFR - supporting the unique role of this hAtg8 protein during receptor trafficking. FEBS Lett. (ePub); doi: 10.1002/1873-3468.14997.
Üffing, A., Gold, L., Gensch, T., Weiergräber, O.H., Hoffmann, S., and Willbold, D. (2024). Highlighting the hidden: monitoring the avidity-driven association of a fluorescent GABARAP tandem with microtubules in living cells. Autophagy Rep. 3, 2348899.
Sundermeyer, L., Bosco, G., Gujar, S., Brocker, M., Baumgart, M., Willbold, D., Weiergräber, O.H., Bellinzoni, M., and Bott, M. (2022). Characteristics of the GlnH and GlnX signal transduction proteins controlling PknG-mediated phosphorylation of OdhI and 2-oxoglutarate dehydrogenase activity in Corynebacterium glutamicum. Microbiol. Spectr. 10, e0267722.
Amariei, D.A., Pozhydaieva, N., David, B., Schneider, P., Classen, T., Gohlke, H., Weiergräber, O.H., and Pietruszka, J. (2022). Enzymatic C3-methylation of indoles using methyltransferase PsmD—Crystal structure, catalytic mechanism, and preparative applications. ACS Catal. 12, 14130−14139.
Weiergräber, O.H., Petrović, D., Kislat, A., Pattky, M., Fabig, J., Batra-Safferling, R., Schulte am Esch, J., Hänel, K., Huhn, C., Strodel, B., Homey, B., and Willbold, D. (2022). Structure and dynamics of human chemokine CCL16—implications for biological activity. Biomolecules 12, 1588.
Brown, H., Chung, M., Üffing, A., Batistatou, N., Tsang, T., Doskocil, S., Mao, W., Willbold, D., Bast, R.C. Jr, Lu, Z., Weiergräber, O.H., and Kritzer, J.A. (2022). Structure-based design of stapled peptides that bind GABARAP and inhibit autophagy. J. Am. Chem. Soc. 144, 14687−14697.
Cukkemane, A., Becker, N., Zielinski, M., Frieg, B., Lakomek, N.-A., Heise, H., Schröder, G.F., Willbold, D., and Weiergräber, O.H. (2021). Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses. Transl. Psychiatry 11, 639.
Freischem, S., Grimm, I., López-Pérez, A., Willbold, D., Klenke, B., Vuong, C., Dingley, A.J., and Weiergräber, O.H. (2021). Interaction mode of the novel monobactam AIC499 targeting penicillin binding protein 3 of Gram-negative bacteria. Biomolecules 11, 1057.
Klinker, S., Stindt, S., Gremer, L., Bode, J.G., Gertzen, C.G.W., Gohlke, H., Weiergräber, O.H., Hoffmann, S., and Willbold, D. (2019). Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication. J. Biol. Chem. 294, 7388−7402.
Abdollahzadeh, I., Schwarten, M., Gensch, T., Willbold, D., and Weiergräber, O.H. (2017). The Atg8 family of proteins—modulating shape and functionality of autophagic membranes. Front. Genet. 8, 109.
Weiergräber, O.H., Schwarten, M., Strodel, B., and Willbold, D. (2017). Investigating structure and dynamics of Atg8 family proteins. Methods Enzymol. 587, 115−142.
Dick, M., Hartmann, R., Weiergräber, O.H., Bisterfeld, C., Classen, T., Schwarten, M., Neudecker, P., Willbold, D., and Pietruszka, J. (2016). Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies. Chem. Sci. 7, 4492−4502.
Michel, M., Schwarten, M., Decker, C., Nagel-Steger, L., Willbold, D., and Weiergräber, O.H. (2015). The mammalian autophagy initiator complex contains 2 HORMA domain proteins. Autophagy 11, 2300−2308.