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Institute of Neuroscience and Medicine

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Positron emission tomography (PET) is a unique modality for imaging normal and diseased metabolical functions in vivo in a quantitative manner. To allow for optimum image quality it is necessary to continuously improve the physical, technological and methological prerequisites of simultaneous recording. For this purpose we develop innovative reconstruction programs and procedures to correct for the different influences on the quantitative accuracy of PET. Furthermore, methods to extract and analyse diagnostically relevant parameters are investigated.
PET is the most sensitive tool for metabolic in vivo imaging, however, magnetic resonance imaging (MRI) delivers unsurpassed anatomical images in addition to functional information complementary to that obtained from PET. The hybrid 3T MR-PET and 9.4T MR-PET scanners installed in our institute open new frontiers by utilizing both imaging modalities simultaneously. This advance in technology mean that new physical and methodological challenges must be addressed. Important issues concern the assessment of the new PET detector technology, corrections for attenuation, scatter and motion correction as well as PET reconstruction guided by MRI. The hybrid scanners enable the simultaneous depiction of activated brain networks, using fMRI, and an interrogation of the biochemistry using PET. Furthermore, the hybrid MR-PET scanner will also serve as a platform to validate MR-based measurements of biochemical and physiological functions with the help of PET.

PET Physics

Research Teams

Technical Aspects of PET

Technical Aspects of Positron-Emission-Tomography

Typically, a PET-scanner consists of a detector ring with 60 cm diameter and 20 cm length inside which the patient is positioned. For brain studies the patient bed is positioned in such a way that the entire brain is within the field of view.


Technical Aspects of MR-PET

The hybrid scanner 3TMR-PET consists of a high resolution BrainPET, newly constructed by Siemens, and a commercial 3T MAGNETOM Trio MRI scanner

Additional Information

Group Leader

Dr. Christoph Lerche

building: 15.9, room: 2001e

phone: +49 2461 61-96524
fax: +49-2461-61-2089


Institut für Neurowissenschaften und Medizin (INM-4)
Forschungszentrum Jülich
52425 Jülich
building: 15.9

Group Photo