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Institute of Neuroscience and Medicine

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Positron emission tomography (PET) is a unique modality for the quantitative in vivo imaging of normal and diseased metabolical functions. To allow for optimum image quality it is necessary to continuously improve the physical, technological, and methodological prerequisites of simultaneous recording. For this purpose, innovative reconstruction programs and procedures are under development to correct for the different influences on the quantitative accuracy of PET. In addition to this, the use of alternative methods to extract and analyse diagnostically relevant parameters are also being studied.

PET is the most sensitive tool for metabolic in vivo imaging; however, magnetic resonance imaging (MRI) delivers unsurpassed anatomical images in addition to functional information, complementary to that obtained from PET. The combination of these devices in the hybrid 3T MR-PET and 9.4T MR-PET scanners installed in our institute, opens up new frontiers by utilising both imaging modalities simultaneously. This advance in technology means that new physical and methodological challenges must be addressed. These include important issues concerning the assessment of the new PET detector technology, corrections for attenuation, scatter and motion correction as well as PET reconstruction guided by MRI. The hybrid scanners enable the simultaneous highlighting of activated brain networks via fMRI and a representation of the biochemistry using PET. Furthermore, by combining MR with PET, the hybrid MR-PET scanner is also able to serve as a platform on which to validate MR-based measurements of biochemical and physiological functions.

PET Physics

Research Teams

Technical Aspects of PET

Technical Aspects of Positron-Emission-Tomography

Typically, a PET-scanner consists of a detector ring with 60 cm diameter and 20 cm length inside which the patient is positioned. For brain studies the patient bed is positioned in such a way that the entire brain is within the field of view.


Technical Aspects of MR-PET

The hybrid scanner 3TMR-PET consists of a high resolution BrainPET, newly constructed by Siemens, and a commercial 3T MAGNETOM Trio MRI scanner

Additional Information

Group Leader

Dr. Christoph Lerche

building: 15.9, room: 2001e

phone: +49 2461 61-96524
fax: +49-2461-61-2089


Institut für Neurowissenschaften und Medizin (INM-4)
Forschungszentrum Jülich
52425 Jülich
building: 15.9

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