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Institute of Neuroscience and Medicine

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Simultaneous MR-PETleft: MRI, right: PET, centre: combination of both

The research and development activities of the Medical Imaging Physics division (INM-4) of the Institute of Neuroscience and Medicine concentrate on the development, experimental validation and the clinical implementation of novel brain imaging methods. The focal points comprise the development of novel methods in the area of ultra-high field Magnetic Resonance Imaging (MRI), Magnetoencephalography (MEG) and the development of hybrid imaging combining MRI with Positron Emission Tomography (PET). Such combinations present unique opportunities for the simultaneous acquisition of structural changes, physiological and biochemical data and provide excellent perspectives for clinical application to neurological diseases, e.g. for the diagnosis and therapy of brain tumours. In cooperation with our partner institutes, novel tracers for PET-MR imaging are investigated in animal experiments and validated by means of autoradiography, immunofluorescence imaging and histological methods.

With MEG patterns of neuronal activities are detected with high temporal resolution. The analysis of such signals provides new insights which contribute to the basic understanding of physiological and pathophysiological activity in the human brain.

The researchers of the INM-4 develop, operate and maintain the scanners of the INM. Additionally, in cooperation with other divisions of the Institute and external researchers, numerous scientific studies into various neuroscientific problems are conducted.

Additional Information

MR-Physics

MRI

The primary aim of the MRI group is the development and implementation of new methods and sequences in Magnetic Resonance Imaging with a focus on the brain.

Technical Aspects of MR-PET

PET

Positron emission tomography (PET) is a unique modality for imaging normal and diseased metabolical functions in vivo in a quantitative manner.

PET-Detector Technology

PET-Detector Technology

Die Arbeitsgruppe befasst sich mit zwei wichtigen Aspekten der Bildgebung mit PET:(1) Entwicklung neuartiger, kompakter und Magnetfeld-kompatibler Detektoren für die PET
(2) Simulation bildgebender Verfahren in der Medizin unter dem Leitmotiv: Das Schicksal der Ereignisse vom primären Detektor zum rekonstruierten Bild unter Berücksichtigung aller physikalischen Effekte und notwendigen Korrekturen.

Brain Tumors

Brain Tumors

The special field of interest of this group is the preclinical and clinical testing of new radiopharmaceuticals for nuclear medicine diagnostics of brain tumors using Positron-Emission-Tomography (PET) and correlation with Magnetic Resonance Imaging (MRI).

MEG-Physik

MEG

Magnetoencephalography (MEG) is a non-invasive measurement for the detection of the tiny magnetic field components originated from the information processes in the living human brain.


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