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Microstructure Research (PGI-5)

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Sharp Images Without Phase Contrast
Jülich, 18 February 2014 – 3D cryo-electron microscopy provides scientists with unique insights into the structure of biological samples. As the cells themselves produce relatively little contrast in images, phase-contrast methods are generally used. These, however, limit resolution capacity and the range of samples that can be used. Scientists at the Ernst Ruska-Centre and the Weizmann Institute of Science in Israel have now presented an alternative method that enables high-resolution images of samples, notably thicker ones, to be recorded in 3D.
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The Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons is a combined development and user facility. More



How the "PICO" microscope works
A unique transmission electron microscope with a resolution of 50 picometres has been available for use by researchers at the ER-C since February 2012.  You can see just how the “PICO” (Advanced Picometre Resolution Project) works in this video. More