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Nanotools for Cell-Chip Communication

Dr. Bernhard Wolfrum

Electrochemical sensorGraphic representation of an electrochemical sensor (green with yellow conductors) that detects neurotransmitter molecules. These molecules are secreted by neurons (dark red).
Source: Forschungszentrum Jülich

The Young Investigator Group develops and investigates nanotechnology tools for chip-based communication with cells and cellular networks. Specifically we are interested in devices that allow electrochemical detection of redox-active molecules. To this end the scientists investigate redox cycling techniques, which benefit from fast diffusion processes on the nanometer scale. Efficient redox cycling approaches in confined geometries, such as nanocavity sensors, show interesting physical phenomena and allow for very sensitive electrochemical detection. The group's goal is to develop biohybrid systems based on these tools to study the release of neurotransmitters. At the same time the scientists are exploring nanoscaled chip-interfaces for functional coupling to cells based on electrical, chemical, and optical communication.

more information (PGI-8)