Publikationen 2017

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The Atg8 Family of Proteins—Modulating Shape and Functionality of Autophagic Membranes
Frontiers in genetics 8, 109 () [10.3389/fgene.2017.00109] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Using Neutron Reflectometry to Characterize Antimicrobial Protein Surface Coatings
The journal of physical chemistry <Washington, DC> / B 121(24), 5908–5916 () [10.1021/acs.jpcb.7b02886]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Structure of a LOV protein in apo-state and implications for construction of LOV-based optical tools
Scientific reports 7, 42971 - () [10.1038/srep42971] DBCoverage  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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The Structure of the Polar Core Mutant R175E and Its Functional Implications
The Structural Basis of Arrestin Functions Cham : Springer International Publishing 143-158 () [10.1007/978-3-319-57553-7_11] BibTeX | EndNote: XML, Text | RIS

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Heterologous expression of the Halothiobacillus neapolitanus carboxysomal gene cluster in Corynebacterium glutamicum
Journal of biotechnology 258, 126-135 () [10.1016/j.jbiotec.2017.03.019] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization
Scientific reports 7, 5979 () [10.1038/s41598-017-06319-4] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Comparison of force fields for Alzheimer's A β42: A case study for intrinsically disordered proteins
Protein science 26(2), 174 - 185 () [10.1002/pro.3064]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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On the potential alternate binding change mechanism in a dimeric structure of Pyruvate Phosphate Dikinase
Scientific reports 7(1), 8020 () [10.1038/s41598-017-08521-w] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Pyroglutamate-modified Aβ(3-42) affects aggregation kinetics of Aβ(1-42) by accelerating primary and secondary pathways
Chemical science 8(7), 4996 - 5004 () [10.1039/C6SC04797A] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Pyroglutamate-Modified Amyloid- β (3–42) Shows α -Helical Intermediates before Amyloid Formation
Biophysical journal 112(8), 1621 - 1633 () [10.1016/j.bpj.2017.03.007]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Surprisingly high stability of the Aβ oligomer eliminating all-d-enantiomeric peptide D3 in media simulating the route of orally administered drugs
European journal of pharmaceutical sciences 107, 203-207 () [10.1016/j.ejps.2017.07.015] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structure and phase transitions of DMPC multilamellar vesicles in the presence of Ca2+ ions
Journal of surface investigation 11(1), 27–37 () [10.1134/S1027451016050499]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Fibril structure of amyloid-ß(1-42) by cryoelectron microscopy
Science 358, 116-119 () [10.1126/science.aao2825]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Mechanism of transmembrane signaling by sensor histidine kinases
Science 356(6342), 6345 () [10.1126/science.aah6345]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Tertiary Interactions in the Unbound Guanine-Sensing Riboswitch Focus Functional Conformational Variability on the Binding Site
Journal of chemical information and modeling 57(11), 2822–2832 () [10.1021/acs.jcim.7b00567]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Rigidity theory for biomolecules: concepts, software, and applications
Wiley interdisciplinary reviews / Computational Molecular Science 7(4), e1311 () [10.1002/wcms.1311] BibTeX | EndNote: XML, Text | RIS

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sFIDA automation yields sub-femtomolar limit of detection for Aβ aggregates in body fluids
Clinical biochemistry 50(4-5), 244-247 () [10.1016/j.clinbiochem.2016.11.001]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Nanoparticle standards for immuno-based quantitation of α-synuclein oligomers in diagnostics of Parkinson's disease and other synucleopathies
Clinica chimica acta 466, 152–159 () [10.1016/j.cca.2017.01.010]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex
Scientific reports 7, 41811 () [10.1038/srep41811] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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A combination of mutational and computational scanning guides the design of an artificial ligand-binding controlled lipase
Scientific reports 7, 42592 - () [10.1038/srep42592] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Abstract 2496: Targeting brain tumor stem cells by interfering with choline metabolism: Evidence for an EMT-choline oncometabolic network
Cancer research 77(13), 2496 () [10.1158/1538-7445.AM2017-2496] BibTeX | EndNote: XML, Text | RIS

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Analysis of anticoagulants for blood-based quantitation of amyloid β oligomers in the sFIDA assay
Biological chemistry 398(4), 465–475 () [10.1515/hsz-2016-0153] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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EDTA aggregates induce SYPRO orange-based fluorescence in thermal shift assay
PLoS one 12, e0177024 () [10.1371/journal.pone.0177024] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase
Journal of the American Chemical Society 139(30), 10514–10525 () [10.1021/jacs.7b05576] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Lactones from the Sponge-Derived Fungus Talaromyces rugulosus
Marine drugs 15, 359 () [10.3390/md15110359] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease
Molecules 22, 1693 () [10.3390/molecules22101693] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Conformational Transitions of the Amyloid-β Peptide Upon Copper(II) Binding and pH Changes
Israel journal of chemistry 57(7-8), 771–784 () [10.1002/ijch.201600108] BibTeX | EndNote: XML, Text | RIS

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Fast iodide-SAD phasing for high-throughput membrane protein structure determination
Science advances 3(5), e1602952 () [10.1126/sciadv.1602952] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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New 2-Methoxy Acetylenic Acids and Pyrazole Alkaloids from the Marine Sponge Cinachyrella sp.
Marine drugs 15, 356 () [10.3390/md15110356] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Cyclic Cystine-Bridged Peptides from the Marine Sponge Clathria basilana Induce Apoptosis in Tumor Cells and Depolarize the Bacterial Cytoplasmic Membrane
Journal of natural products 80(11), 2941–2952 () [10.1021/acs.jnatprod.7b00477]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa
Journal of natural products 80(1), 169–180 () [10.1021/acs.jnatprod.6b00809]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Integral Membrane Proteins Can Be Crystallized Directly from Nanodiscs
Journal of crystal growth 17(3), 945–948 () [10.1021/acs.cgd.6b01631] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Protein Stability and Unfolding Following Glycine Radical Formation
Molecules 22(4), 655 () [10.3390/molecules22040655] special issue: "Biomolecular Simulations" OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Multiple WW domains of Nedd4-1 undergo conformational exchange that is quenched upon peptide binding
FEBS letters 591(11), 1573 - 1583 () [10.1002/1873-3468.12664]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Shuffling Active Site Sub-State Populations Impacts Catalytic Activity: The Case of Glucose Oxidase
ACS catalysis 7, 6188–6197 () [10.1021/acscatal.7b01575]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Ca2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy
Proceedings of the National Academy of Sciences of the United States of America 114, 6782-6787 () [10.1073/pnas.1700868114]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Molecular Dynamics Simulations Reveal Key Roles of the Interleukin-6 Alpha Receptor in the Assembly of the Human Interleukin-6 Receptor Complex
The journal of physical chemistry letters 121, 8113-8122 () [10.1021/acs.jpcb.7b05732]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Expression and purification of arrestin in yeast Saccharomyces cerevisiae
Methods in Cell Biology - G Protein-Coupled Receptors San Diego, US : Academic Press 159-172 () BibTeX | EndNote: XML, Text | RIS

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Fluorescence correlation spectroscopy reveals a cooperative unfolding of monomeric amyloid-β 42 with a low Gibbs free energy
Scientific reports 7, 2154 () [10.1038/s41598-017-02410-y] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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$^{1}$H, $^{13}$C, and $^{15}$N backbone and sidechain resonance assignments of a monomeric variant of E. coli deoxyribose-5-phosphate aldolase
Biomolecular NMR assignments 11(2), 197-201 () [10.1007/s12104-017-9747-6]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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6 - Sodium and Engineered Potassium Light-Driven Pumps
Optogenetics from Neuronal Function to Mapping and Disease Biology Massachusetts : Cambridge University Press 77-78 () OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Contribution of single amino acid and codon substitutions to the production and secretion of a lipase by Bacillus subtilis
Microbial cell factories 16(1), 160 () [10.1186/s12934-017-0772-z] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Learning from simulations
OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structural basis for the regulatory interactions of proapoptotic Par-4
Cell death and differentiation 24, 1540–1547 () [10.1038/cdd.2017.76] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Conformational Heterogeneity in a Fully Complementary DNA Three-Way Junction with a GC-Rich Branchpoint.
Biochemistry 56(37), 4985–4991 () [10.1021/acs.biochem.7b00677] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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New amide and dioxopiperazine derivatives from leaves of Breynia nivosa
Fitoterapia 122, 16-19 () [10.1016/j.fitote.2017.08.009]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology
Scientific reports 7(1), 16275 () [10.1038/s41598-017-16565-1] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Enhancing the Catalytic Deamination Activity of APOBEC3C Is Insufficient to Inhibit Vif-Deficient HIV-1
Journal of molecular biology 429(8), 1171–1191 () [10.1016/j.jmb.2017.03.015]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Photo-voltage of highly-oriented bacteriorhodopsin in purple membranes: Possibilities for bio solar cells
Optoelectronics and advanced materials - rapid communications 11(1-2), 65-67 ()  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Structural insights into ion conduction by channelrhodopsin 2
Science 358(6366), eaan8862 () [10.1126/science.aan8862]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Secondary Metabolites of the Lichen-Associated Fungus Apiospora montagnei
Tetrahedron letters 58(17), 1702–1705 () [10.1016/j.tetlet.2017.03.052]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Investigating Structure and Dynamics of Atg8 Family Proteins
New York, NY [u.a.] : Elsevier, Methods in enzymology 587, 115–142 () [10.1016/bs.mie.2016.09.056]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Structural characterization of recombinant fibrillar human Islet Amyloid Polypeptide by solid-state Nuclear Magnetic Resonance Spectroscopy
114 p () = Dissertation, HHU Düsseldorf, 2017 BibTeX | EndNote: XML, Text | RIS

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Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution
Scientific reports 7, 2493 () [10.1038/s41598-017-02370-3] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Opposed effects of dityrosine formation in soluble and aggregated alpha-synuclein on fibril growth
Journal of molecular biology 429, 3018-3030 () [10.1016/j.jmb.2017.09.005] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Influence of solubilization and AD-mutations on stability and structure of human presenilins
Scientific reports 7(1), 17970 () [10.1038/s41598-017-18313-x] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations
The journal of biological chemistry 292, 6468–6477 () [10.1074/jbc.M116.773903]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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High-efficient production and biophysical characterisation of nicastrin, and ist interaction with APPC100
Scientific reports 7, 44297 () [10.1038/srep44297] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Letzte Änderung: 23.05.2022