Publikationen 2023

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Fast Motions Dominate Dynamics of Intrinsically Disordered Tau Protein at High Temperatures
Chemistry - a European journal 29(17), e202203493 () [10.1002/chem.202203493] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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The Avidity of Autoreactive Alpha-Synuclein Antibodies in Leucine-Rich Repeat Kinase 2 Mutation Carriers Is Not Altered Compared to Healthy Controls or Patients with Parkinson’s Disease
Biomolecules 13(9), 1303 - () [10.3390/biom13091303] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer’s Disease and Other Tauopathies
International journal of molecular sciences 24(3), 2161 - () [10.3390/ijms24032161] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Development and implementation of an internal quality control sample to standardize oligomer-based diagnostics of Alzheimer's disease
Diagnostics 13(10), 1702 - () [10.3390/diagnostics13101702] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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RNA-Processing DNAzymes
RNA Structure and Function / Barciszewski, Jan (Editor) ; Cham : Springer International Publishing, 2023, Chapter 28 ; ISSN: 2197-9731=2197-9758 ; ISBN: 978-3-031-36389-4=978-3-031-36390-0 ; doi:10.1007/978-3-031-36390-0 Cham : Springer International Publishing, RNA Technologies 14, 629 - 643 () [10.1007/978-3-031-36390-0_28] BibTeX | EndNote: XML, Text | RIS

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Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1–42) Amyloid Fibrils
Journal of the American Chemical Society 145(4), 2161–2169 () [10.1021/jacs.2c09231] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Maturation of amyloid β fibrils alters their molecular stability
Physical chemistry, chemical physics 25, 15099-15103 () [10.1039/D3CP01276J] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Aß oligomers peak in early clinical stages of Alzheimer´s disease and proceed Tau pathology
Alzheimer's and dementia 19(S24), e082907 () [10.1002/alz.082907]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The architecture of the 10‐23 DNA zyme and its implications for DNA ‐mediated catalysis
The FEBS journal 290(8), 2011-2021 () [10.1111/febs.16698] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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The Importance of Epigallocatechin as a Scaffold for Drug Development against Flaviviruses
Pharmaceutics 15(3), 803 - () [10.3390/pharmaceutics15030803] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Discovery of All- d -Peptide Inhibitors of SARS-CoV-2 3C-like Protease
ACS chemical biology 18(2), 315 - 330 () [10.1021/acschembio.2c00735] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Tau protein aggregation associated with SARS-CoV-2 main protease
bioRxiv beta XX, XX () [10.1101/2023.03.04.531078] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Tau protein aggregation associated with SARS-CoV-2 main protease
PLOS ONE 18(8), e0288138 - () [10.1371/journal.pone.0288138] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Cumulative Millisecond-Long Sampling for a Comprehensive Energetic Evaluation of Aqueous Ionic Liquid Effects on Amino Acid Interactions
Journal of chemical information and modeling 63(1), 281–298 () [10.1021/acs.jcim.2c01123] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Amyloid fibril formation kinetics of low-pH denatured bovine PI3K-SH3 monitored by three different NMR techniques
Frontiers in molecular biosciences 10-2023, 1254721 () [10.3389/fmolb.2023.1254721] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Editorial: The biochemistry of amyloids in neurodegenerative diseases, volume II
Frontiers in neuroscience 17, 1236518 () [10.3389/fnins.2023.1236518] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Flotillin-associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes
mSystems 8(3), e00008-23 () [10.1128/msystems.00008-23] DBCoverage BibTeX | EndNote: XML, Text | RIS

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Nucleation of α-Synuclein Amyloid Fibrils Induced by Cross-Interaction with β-Hairpin Peptides Derived from Immunoglobulin Light Chains
International journal of molecular sciences 24(22), 16132 - () [10.3390/ijms242216132] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Residue alterations within a conserved hydrophobic pocket influence light, oxygen, voltage photoreceptor dark recovery
Photochemical & photobiological sciences 22, 713-727 () [10.1007/s43630-022-00346-5] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment
Toxicology letters 373, 160-171 () [10.1016/j.toxlet.2022.11.018] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Measuring pico-Newton Forces with Lipid Anchors as Force Sensors in Molecular Dynamics Simulations
The journal of physical chemistry / B 127(18), 4081 - 4089 () [10.1021/acs.jpcb.3c00063] BibTeX | EndNote: XML, Text | RIS

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Comparative molecular dynamics simulations of pathogenic and non-pathogenic huntingtin protein monomers and dimers
Frontiers in molecular biosciences 10, 1143353 () [10.3389/fmolb.2023.1143353] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers
Journal of the American Chemical Society 145(33), 18340 - 18354 () [10.1021/jacs.3c03980] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Mechanisms of inward transmembrane proton translocation
Nature structural & molecular biology 30(7), 970 - 979 () [10.1038/s41594-023-01020-9] BibTeX | EndNote: XML, Text | RIS

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Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs – A model of sporadic Alzheimer’s disease
Heliyon 9(8), e18443 - () [10.1016/j.heliyon.2023.e18443] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Combining skin and olfactory α-synuclein seed amplification assays (SAA)—towards biomarker-driven phenotyping in synucleinopathies
npj Parkinson's Disease 9(1), 79 () [10.1038/s41531-023-00519-8] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Combining structural and coevolution information to unveil allosteric sites
Chemical science 14(25), 7057-7067 () [10.1039/D2SC06272K] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Functional reconstitution and structural characterization of the plant hormone receptor ETR1 in lipid nanodiscs
Chemical communications 59(61), 9344 - 9347 () [10.1039/D3CC02619A] Embargoed OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2
Scientific reports 13(1), 679 () [10.1038/s41598-023-27520-8] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore
Proceedings of the National Academy of Sciences of the United States of America 120(27), e2221595120 () [10.1073/pnas.2221595120] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET
Communications biology 6(1), 362 () [10.1038/s42003-023-04727-z] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Amyloid oligomers as on-pathway precursors or off-pathway competitors of fibrils
Frontiers in molecular biosciences 10, 1120416 () [10.3389/fmolb.2023.1120416] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Editorial for the special issue “A Celebration of Women in Biophysical Chemistry”
Biophysical chemistry 292, 106929 - () [10.1016/j.bpc.2022.106929] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Pyroglutamate-modified amyloid β(3–42) monomer has more β-sheet content than the amyloid β(1–42) monomer
Physical chemistry, chemical physics 25(24), 16483 - 16491 () [10.1039/D2CP05961D] BibTeX | EndNote: XML, Text | RIS

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Differentiation of subnucleus-sized oligomers and nucleation-competent assemblies of the A β peptide
Biophysical journal 122(2), 269 - 278 () [10.1016/j.bpj.2022.12.020] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Disrupted‐in‐schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first‐episode psychosis
Psychiatry and clinical neurosciences 77(12), 665 - 671 () [10.1111/pcn.13594] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case–Control Study Based on German Health Claims Data
Journal of Alzheimer's disease 93(4), 1329 - 1339 () [10.3233/JAD-221153]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Familial Alzheimer’s Disease-Related Mutations Differentially Alter Stability of Amyloid-Beta Aggregates
The journal of physical chemistry letters 14, 1427 - 1435 () [10.1021/acs.jpclett.2c03729] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Transition Networks Unveil Disorder-to-Order Transformations in Aβ Caused by Glycosaminoglycans or Lipids
International journal of molecular sciences 24(14), 11238 - () [10.3390/ijms241411238] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool
npj Parkinson's Disease 9(1), 14 () [10.1038/s41531-023-00458-4] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Fibril core regions in engineered α-synuclein dimer are crucial for blocking of fibril elongation
BBA advances 4, 100110 - () [10.1016/j.bbadva.2023.100110] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Allosteric communication induced by GTP binding sets off a closed-to-open transition in a bacterial dynamin-like protein
[10.1101/2023.01.16.524228] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Integrative modeling of guanylate binding protein dimers
Protein science 32(12), e4818 () [10.1002/pro.4818] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Effects of ion type and concentration on the structure and aggregation of the amyloid peptide A β16−22$$ {\boldsymbol{\beta}}_{16-22} $$
Proteins 16-22, prot.26635 () [10.1002/prot.26635] BibTeX | EndNote: XML, Text | RIS

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Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains
BMC biology 21(1), 21 () [10.1186/s12915-022-01506-w] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Intrinsic Disorder of the Neuronal SNARE Protein SNAP25a in its Pre-fusion Conformation
Journal of molecular biology 435(10), 168069 - () [10.1016/j.jmb.2023.168069] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Ferritin self-assembly, structure, function, and biotechnological applications
International journal of biological macromolecules 224, 319 - 343 () [10.1016/j.ijbiomac.2022.10.126] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Evaluation of the 18F-Labeled Analog of the Therapeutic All-d-enantiomeric Peptide RD2 for Amyloid β Imaging
European journal of pharmaceutical sciences 184, 106421 () [10.1016/j.ejps.2023.106421] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Oral Treatment with d-RD2RD2 Impedes Early Disease Mechanisms in SOD1*G93A Transgenic Mice but Does Not Prolong Survival
Biomedicines 11(4), 995 - () [10.3390/biomedicines11040995] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Cryo-EM of Aβ Fibrils from Mouse Models find tg-APPArcSwe fibrils resemble those found in sporadic Alzheimer's disease patients
Nature neuroscience 26, 2073-2080 () [10.1038/s41593-023-01484-4] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Discovery of novel amino acid production traits by evolution of synthetic co-cultures
Microbial cell factories 22(1), 71 () [10.1186/s12934-023-02078-2] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Letzte Änderung: 17.01.2023