The main focus of radiopharmaceutical production at the INM-5 is on the preparation of clinical trials (radiotracer) for the Positron Emission Tomography (PET) as for the FZJ internal service (Institute of Neuroscience and Medicine: Medicine (INM-2 and 3), Clinics for medicine (KME) as well as for external university hospitals (Universities of Aachen, Duesseldorf, Muenster etc.).
In general, radiopharmaceuticals (radiotracers) are synthesized by coupling a short-lived radionuclide to anorganic compound (e.g. a drug or a metabolic substance like glucose, amino acid or fatty acids). Due to the high amount of radioactivity, these labelling reactions are performed in remotely controlled synthesis apparatus, which are located in lead shielded cells (so called hot cells).