Dr. Oleg Dmytrenko

2018–2025 Postdoc in RNA Synthetic Biology

Helmholtz Institute for RNA-based Infection Research, Würzburg, Germany

2008–2018 PhD in Organismic and Evolutionary Biology

Harvard University, Cambridge, MA, USA

2009–2010 Visiting Scientist

Department of Civil and Environmental Engineering, MIT, Cambridge, MA, USA

2007–2008 Graduate Researcher

Max Planck Institute for Marine Microbiology, Bremen, Germany

2005–2007 BSc in Biology

Jacobs University Bremen, Germany

Scholz P., Thompson J., Crosby K.T., … Dmytrenko O., et al. RNA-triggered cell killing with CRISPR–Cas12a2. Nature (2026). https://doi.org/10.1038/s41586-026-10466-y

Dmytrenko O., Yuan B., Crosby K.T., et al. RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity. Nature 649, 1312–1321 (2026). https://doi.org/10.1038/s41586-025-09852-9

Eggenschwiler R., Hoffmann T., Dmytrenko O., Opitz M., Ackel-Zakour M., et al. PAM-interacting domain turn-helix 51 motifs can improve Cas9–SpRY activity. Nucleic Acids Research 53, gkaf782 (2025). https://doi.org/10.1093/nar/gkaf782

Schut F.T., Hallmark T., Dmytrenko O., Jackson R.N., Beisel C.L. Purification and in vivo, cell-free, and in vitro characterization of CRISPR–Cas12a2. Methods in Enzymology 712, 143–181 (2025). https://doi.org/10.1016/bs.mie.2025.01.032

Khakimzhan A., Izri Z., Thompson S., … Dmytrenko O., et al. Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins. Communications Biology 7, 1005 (2024). https://doi.org/10.1038/s42003-024-06690-9

Dmytrenko O., Neumann G.C., Hallmark T., et al. Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613, 588–594 (2023). https://doi.org/10.1038/s41586-022-05559-3