Dr. rer. nat. Guanxiao Qi

Dr. Guanxiao Qi obtained his bachelor’s and master’s degrees in physics from Southeast University, China. In 2007, he moved to RWTH Aachen University to pursue doctoral studies under the supervision of Prof. Dr. Dirk Feldmeyer. In 2011, he was awarded the degree of Dr. rer. nat. in biology with summa cum laude. Since 2014, he has been working as a research associate at the Research Centre Jülich.

Yang, D. Q., Qi, G. X., Ort, J., Witzig, V., Bak, A., Delev, D., Koch, H. & Feldmeyer, D. Modulation of large rhythmic depolarization in human large basket cells by norepinephrine and acetylcholine. Commun Biol 7 (1), 885, doi:10.1038/s42003-024-06546-2, (2024).

Jiang, H. J., Qi, G. X., Duarte, R., Feldmeyer, D. & van Albada, S. A layered microcircuit model of somatosensory cortex with three interneuron types and cell-type-specific short-term plasticity. Cereb Cortex 34, bhae378, doi:10.1093/cercor/bhae378, (2024).

Qi, G. X. ^*, Yang, D. Q. ^*, Messore, F., Bast, A., Yanez, F., Oberlander, M. & Feldmeyer, D. FOXP2-immunoreactive corticothalamic neurons in neocortical layers 6a and 6b are tightly regulated by neuromodulatory systems. iScience 28 (1), 111646, doi:10.1016/j.isci.2024.111646, (2024).

Yang, D. Q. ^*, Qi, G. X. ^*, Delev, D., Maskos, U. & Feldmeyer, D. Linking altered neuronal and synaptic properties to nicotinic receptor Alpha5 subunit gene dysfunction: a translational investigation in rat mPFC and human cortical layer 6. Transl Psychiatry 15 (1), 12, doi:10.1038/s41398-025-03230-9, (2025).

Balduin, C., Qi, G. X., Schoneck, M., Trinkel, V., Schemmert, S., Guzman, G.A., Bungert-Plumke, S., Klussendorf, M., Neumaier, B., Feldmeyer, D., Shah, N.J., Stauber, T., Langen, K.-J., Guzman, R.E., Willuweit, A., Disruption of ClC-3-mediated 2Cl^-/H⁺ exchange leads to behavioural deficits and thalamic atrophy. Sci Rep 15 (1), 33326, doi:10.1038/s41598-025-19757-2, (2025).

Qi, G. X., Diaz-Castillo, A., Aretzweiler, C., Steinmetz, L., Bungert-Plumke, S., Muller, F., Feldmeyer, D. & Guzman, R. Endosomal 2Cl^-/H⁺ exchangers regulate neuronal excitability by tuning K_v7/KCNQ channel density. Brain, doi:10.1093/brain/awaf243, (2025).

Qi, G. X. ^*, Yang, D. Q. ^*, Bak, A. ^*, Hucko, W., Delev, D., Hamou, H., Feldmeyer, D. & Koch, H. Transport-Related Effects on Intrinsic and Synaptic Properties of Human Cortical Neurons: A Comparative Study. J Physiol (accepted).

^* Equal contribution