Longitudinal multimodal investigation of communication impairments

The aim is to investigate and differentiate between different aspects/influencing factors of communication impairments

Patients with ataxia / healthy adults

University Hospital Düsseldorf/ Research Center Juelich

Gait and Balance training study

This study investigates the impact of a 3-week-video-based gait- and balance training on gait- and balance performance.

Patients with ataxia / Parkinson’s syndrome or healthy adults

University Hospital Düsseldorf

TreatPOLR3A - NHS

The aim of this multicenter patient registry is to determine the various symptoms and the natural course of POLR3A-associated spastic ataxia (in the presence of the c.1909+22G>A variant)

Patients with POLR3A-associated spastic ataxia and carriers of the 1909+22G>A gene variant

University Hospital Düsseldorf

ARCA-Register

n this DZNE network research project (Autosomal Recessive Cerebellar Ataxia Registry, ARCA registry), modern methods are being used to search for new ataxia genes and biomarkers in autosomal recessive ataxias and early onset ataxias with onset before the age of 40.

Patients with (early-onset) cerebellar ataxias

University Hospital Düsseldorf

SCA-Registry

The goals of the SCA (Spinocerebellar Ataxias) Registry (headed by the DZNE) are to characterize the natural history of the disease, identify prognostic factors, and develop novel imaging and biochemical biomarkers. At-risk individuals are also included to study the preclinical disease phase.

Patients with spinocerebellar ataxia (or gene carriers)

University Hospital Düsseldorf