Dynamics and interaction of (bio)macromolecular systems at and in interfaces
About
The properties of synthetic and biological nanoscopic particles suspended in solvents differ significantly in the immediate vicinity of an interface from their behaviour in the bulk. These changes are caused by static and hydrodynamic interactions between the particles and the interface and ultimately lead to interface-induced changes in macroscopic material properties such as rheology or phase behaviour. We investigate the underlying mechanisms on the nanometre scale of biological, or biologically inspired and synthetically tailored model systems using computer simulations and interface-sensitive scattering techniques.
These effects are not only of scientific interest, but also play a role in many technological, biological and biomedical processes, from membrane filtration to the approach of a virus or drug carrier to a cell wall to the movement of proteins in membranes.
With our work, we want to contribute to a fundamental microscopic understanding of the physical mechanisms underlying such processes.
Research Topics
Members
Quasi-two-dimensional dispersions of Brownian particles with competitive interactions: phase behavior and structural properties, Z. Tan et al., Soft matter 20, 9528 (2024) DOI: 10.1039/D4SM00736K.
Analysing Sources of Error in Total Internal Reflection Microscopy (TIRM) Experiments and Data Analysis, J. A. Rivera-Morán et al., Polymers 15, 4028 (2023). DOI: 10.3390/polym15214208
Polyelectrolyte Complexes from Oppositely Charged Filamentous Viruses, H. Anop et al., Langmuir 39, 4545 (2023). DOI: 10.1021/acs.langmuir.2c02790
Geometrical Influence on Particle Transport in Cross-Flow Ultrafiltration: Cylindrical and Flat Sheet Membranes. G. W. Park et al., Membranes 11, 960 - (2021) DOI: 10.3390/membranes11120960
On the effect of morphology and particle-wall interaction on colloidal near-wall dynamics, J. A. Rivera-Morán et al., Soft Matter 17,10301 (2021). DOI: 10.1039/d1sm01191j
Probing nonlinear velocity profiles of shear-thinning, nematic platelet dispersions in Couette flow using x-ray photon correlation spectroscopy, Y. Chen et al., Physics of fluids 33, 063102 (2021). DOI: 10.1063/5.0050942