Institute of Neurosciences and Medicine (INM)

Molecular Organization of the Brain (INM-2)

Publications 2025

Journal Article Akradi, M. ; Farzane-Daghigh, T. ; Ebneabbasi, A. ; Bi, H.FZJ* ; Drzezga, A.FZJ* ; Mander, B. A. ; Eickhoff, S. B.FZJ* ; Tahmasian, M. (Corresponding author)FZJ*
How is self-reported sleep-disordered breathing linked with biomarkers of Alzheimer’s disease?
Neurobiology of aging 154, 16-24 (2025) [10.1016/j.neurobiolaging.2025.06.006]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Asendorf, A. L. ; Guerra, E. ; Dzialas, V. ; Banwinkler, M. ; Theis, H. ; Hagemann, N. ; Möllenhoff, K. ; van Eimeren, T. ; Hönig, M. (Corresponding author)FZJ*
Physical activity and network attack tolerance preserve motor function in Parkinson’s disease: A pilot study
npj Parkinson's Disease 11(1), 183 (2025) [10.1038/s41531-025-01033-9]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Bauer, T. ; Brendel, M. ; Zaganjori, M. ; Bernhardt, A. M. ; Jäck, A. ; Stöcklein, S. ; Scheifele, M. ; Levin, J. ; van Eimeren, T. ; Drzezga, A.FZJ* ; Sabri, O. ; Barthel, H. ; Perneczky, R. ; Höglinger, G. ; Franzmeier, N. ; Gnörich, J. (Corresponding author)
Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [18F]PI-2620 PET Scans
NeuroImage 306, 121001 (2025) [10.1016/j.neuroimage.2025.121001]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Bollack, A. (Corresponding author) ; Shekari, M. ; Collij, L. E. ; Luckett, E. ; García, D. V. ; Markiewicz, P. ; Wolz, R. ; Yaqub, M. ; Wink, A. M. ; Gismondi, R. ; Stephens, A. ; Visser, P. J. ; Mett, A. ; Drzezga, A.FZJ* ; Buckley, C. ; Gispert, J. D. ; Farrar, G. ; Barkhof, F.
Implementing robust amyloid PET quantification in multi‐center studies: AMYPAD approach to address data acquisition, processing, interpretation and data sharing challenges
Alzheimer's & dementia / Translational research & clinical interventions 11(4), e70190 (2025) [10.1002/trc2.70190]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Buchert, R. ; Drzezga, A.FZJ* ; Schreckenberger, M. ; Langen, K. J.FZJ* ; Meyer, P. T.
The Status of Neuroimaging with SPECT and PET in Germany: Results from the 1st Survey on Nuclear Neuroimaging in Germany in 2023
Nuklearmedizin -, a-2566-1487 (2025) [10.1055/a-2566-1487]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Collij, L. E. ; Bischof, G. N. ; Altomare, D. ; Bader, I. ; Battle, M. ; Vállez García, D. ; Lopes Alves, I. ; Wolz, R. ; Gismondi, R. ; Stephens, A. ; Walker, Z. ; Scheltens, P. ; Nordberg, A. ; Gispert, J. D. ; Drzezga, A.FZJ* ; Perissinotti, A. ; Morbelli, S. ; Buckley, C. ; Garibotto, V. ; Frisoni, G. B. ; Farrar, G. ; Barkhof, F. (Corresponding author)
Quantification Supports Amyloid PET Visual Assessment of Challenging Cases: Results from the AMYPAD Diagnostic and Patient Management Study
Journal of nuclear medicine 66(1), 110 - 116 (2025) [10.2967/jnumed.124.268119]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Patent Cukkemane, A. A.FZJ* ; Elmenhorst, D.FZJ* ; Elmenhorst, E.-M.Extern*
Biomarker für die Diagnose von Schlafstörungen
Fulltext BibTeX | EndNote: XML, Text | RIS

Journal Article Czernin, J. ; Anderson, C. J. ; Badawi, R. D. ; Barthel, H. ; Bengel, F. M. ; Beyer, T. ; Buvat, I. ; Calais, J. ; Dorbala, S. ; Drzezga, A. E.FZJ* ; Herrmann, K. ; Hope, T. A. ; Jadvar, H. ; Mankoff, D. A. ; Schelbert, H. R. ; Weber, W. A.
Funding Reductions Threaten the Future of Medical Innovation
Journal of nuclear medicine 66(6), 829 - 829 (2025) [10.2967/jnumed.125.270157]2025 Files BibTeX | EndNote: XML, Text | RIS

Journal Article de Bruin, H. ; Groot, C. ; Barthel, H. ; et al
Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease
Brain 148(11), 3893 - 3912 (2025) [10.1093/brain/awaf279]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Doering, E.FZJ* ; Hönig, M.FZJ* ; Cole, J. H. ; Drzezga, A.FZJ*
When Age Is More Than a Number: Acceleration of Brain Aging in Neurodegenerative Diseases
Journal of nuclear medicine 66(10), 1516 - 1521 (2025) [10.2967/jnumed.125.270325]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Doering, E.FZJ* ; Hoenig, M. C.FZJ* ; Giehl, K.FZJ* ; Dzialas, V. ; Andrassy, G. ; Bader, A. ; Bauer, A.FZJ* ; Elmenhorst, D.FZJ* ; Ermert, J.FZJ* ; Frensch, S.FZJ* ; Jäger, E. ; Jessen, F. ; Krapf, P.FZJ* ; Kroll, T.FZJ* ; Lerche, C.FZJ* ; Lothmann, J. ; Matusch, A.FZJ* ; Neumaier, B.FZJ* ; Onur, O. A.FZJ* ; Ramirez, A. ; Richter, N.FZJ* ; Sand, F. ; Tellmann, L.FZJ* ; Theis, H. ; Zeyen, P. ; van Eimeren, T.FZJ* ; Drzezga, A. (Corresponding author)FZJ* ; Bischof, G. N. (Corresponding author)
“Fill States”: PET-derived Markers of the Spatial Extent of Alzheimer Disease Pathology
Radiology 314(3), e241482 (2025) [10.1148/radiol.241482]2025 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Drzezga, A. (Corresponding author)FZJ* ; Barthel, H.
Imaging and Fluid Biomarkers of Alzheimer Disease: Complementation Rather Than Competition
Journal of nuclear medicine 66(Supplement 2), S32 - S44 (2025) [10.2967/jnumed.125.270152]2025 Fulltext BibTeX | EndNote: XML, Text | RIS

Journal Article Dzialas, V. ; Bischof, G. N. ; Möllenhoff, K. ; Drzezga, A.FZJ* ; van Eimeren, T. (Corresponding author)FZJ*
Dopamine Transporter Imaging as Objective Monitoring Biomarker in Parkinson's Disease
Annals of neurology 98(1), 120 - 135 (2025) [10.1002/ana.27223]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Fischer, F. U. (Corresponding author) ; Kollmann, B. ; Wolf, D. ; Sebastian, A. ; Knaepen, K. ; Riedel, D. ; Mierau, A. ; Ruffini, N. ; Endres, K. ; Winter, J. ; Strüder, H. K. ; Bischof, G. N. ; Faraza, S. ; Baier, B. ; Binder, H. ; Drzezga, A.FZJ* ; Teipel, S. ; Fellgiebel, A. ; Tüscher, O.
Cognitive training gain transfer in cognitively healthy aging: per protocol results of the German AgeGain study
Frontiers in aging neuroscience 17, 1587395 (2025) [10.3389/fnagi.2025.1587395]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Gordjinejad, A. (Corresponding author)FZJ* ; Matusch, A.FZJ* ; Kleedörfer, S. ; Patel, H. J. ; Drzezga, A.FZJ* ; Elmenhorst, D.FZJ* ; Binkofski, F.FZJ* ; Bauer, A.FZJ*
Hemispheric asymmetry in high-energy phosphate consumption during sleep-deprivation is balanced by creatine
Frontiers in neuroscience 19, 1515761 (2025) [10.3389/fnins.2025.1515761]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Heilinger, J. ; Roth, K. S. ; Weis, H. ; Fink, A. ; Weindler, J. ; Dietlein, F. ; Krapf, P.FZJ* ; Schomäcker, K. ; Neumaier, B.FZJ* ; Dietlein, M. ; Drzezga, A.FZJ* ; Kobe, C. (Corresponding author)Extern*
Do you know your PSMA-tracer? Variability in the biodistribution of different PSMA ligands and its potential impact on defining PSMA-positivity prior to PSMA-targeted therapy
EJNMMI Research 15(1), 4 (2025) [10.1186/s13550-024-01190-7]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Kling, A. ; Kusche-Palenga, J. ; Palleis, C. ; Jäck, A. ; Bernhardt, A. M. ; Frontzkowski, L. ; Roemer, S. N. ; Slemann, L. ; Zaganjori, M. ; Scheifele, M. ; Paeger, L. ; Bischof, G. N. ; van Eimeren, T.FZJ* ; Drzezga, A.FZJ* ; Sabri, O. ; Rullmann, M. ; Barthel, H. ; Levin, J. ; Herms, J. ; Franzmeier, N. ; Höglinger, G. ; Roeber, S. ; Brendel, M. ; Gnörich, J. (Corresponding author)
Exploring the origins of frequent tau-PET signal in vermal and adjacent regions
European journal of nuclear medicine and molecular imaging 52(10), 3519 - 3533 (2025) [10.1007/s00259-025-07199-x]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Michno, M.FZJ* ; Schmitz, J. ; Foerges, A. L.FZJ* ; Beer, S.FZJ* ; Jordan, J. ; Neumaier, B.FZJ* ; Drzezga, A.FZJ* ; Aeschbach, D. ; Bauer, A.FZJ* ; Tank, J. ; Weis, H. ; Elmenhorst, E.-M. ; Elmenhorst, D.FZJ*
Effect of Acute Hypoxia Exposure on the Availability of A1 Adenosine Receptors and Perfusion in the Human Brain
Journal of nuclear medicine 66(1), 142 - 149 (2025) [10.2967/jnumed.124.268455]2025 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Michno, M. (Corresponding author)FZJ* ; Schmitz, J. ; Foerges, A. L.FZJ* ; Beer, S.FZJ* ; Jordan, J. ; Neumaier, B.FZJ* ; Drzezga, A.FZJ* ; Aeschbach, D. ; Bauer, A.FZJ* ; Tank, J. ; Weis, H. ; Elmenhorst, E.-M. ; Elmenhorst, D.FZJ*
Sauerstoffmangel im Gehirn: Perfusion und Verfügbarkeit von A1-Adenosinrezeptoren
Flugmedizin, Tropenmedizin, Reisemedizin 32(03), 146 - 154 (2025) [10.1055/a-2547-3678]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Moscoso, A. ; Heeman, F. ; Raghavan, S. ; et al
Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity
The journal of the American Medical Association 334(3), 229 - (2025) [10.1001/jama.2025.7817]2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Ossenkoppele, R. ; Coomans, E. M. ; Apostolova, L. G. ; et al
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex
Nature neuroscience 28(8), 1610 - 1621 (2025) [10.1038/s41593-025-02000-6]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Reimann, G. ; Hoseini, A. ; Koçak, M. ; Beste, M. ; Küppers, V.FZJ* ; Rosenzweig, I. ; Elmenhorst, D.FZJ* ; Pires, G. N. ; Laird, A. R. ; Fox, P. T. ; Spiegelhalder, K. ; Reetz, K.FZJ* ; Eickhoff, S.FZJ* ; Müller, V.FZJ* ; Tahmasian, M. (Corresponding author)FZJ*
Distinct convergent brain alterations in sleep disorders and sleep deprivation
JAMA psychiatry 82(7), 681-691 (2025) [10.1001/jamapsychiatry.2025.0488]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Schmidt, C. C. (Corresponding author)FZJ* ; Bardakan, M. M.FZJ* ; Jaeger, E. ; Richter, N. ; Bischof, G. N. ; Giehl, K.FZJ* ; Onur, O. A. ; Jessen, F. ; Fink, G. R.FZJ* ; Drzezga, A.FZJ* ; Weiss-Blankenhorn, P.FZJ*
Apraxic deficits predict general cognitive impairment in patients with biomarker-verified Alzheimer’s pathology
Journal of neurology 272(10), 654 (2025) [10.1007/s00415-025-13401-9]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Tutas, J. ; Tolve, M. ; Özer-Yildiz, E. ; Ickert, L. ; Klein, I. ; Silverman, Q. ; Liebsch, F. ; Dethloff, F. ; Giavalisco, P. ; Endepols, H.FZJ* ; Georgomanolis, T. ; Neumaier, B.FZJ* ; Drzezga, A.FZJ* ; Schwarz, G. ; Thorens, B. ; Gatto, G. ; Frezza, C. ; Kononenko, N. L. (Corresponding author)
Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity
Nature metabolism 7, 297–320 (2025) [10.1038/s42255-024-01196-4]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Wiels, W. A. ; Oomens, J. E. ; Engelborghs, S. ; et al
Depressive Symptoms and Amyloid Pathology
JAMA psychiatry 82(3), 296 - 310 (2025) [10.1001/jamapsychiatry.2024.4305]2025 BibTeX | EndNote: XML, Text | RIS

Last Modified: 08.01.2025