Publikationen 2025
Master Thesis
Microfluidic Platform for the Study of Stable Co-Cultures: Phototrophic and Heterotrophic Microorganisms in Sucrose-Driven Carbon Exchange
95 p. (2025) = Masterarbeit, Universität Bonn, 2025
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Journal Article
Continuous cultivation of defined mixed bacterial cultures for upcycling polyurethane and polyethylene terephthalate monomers to polyhydroxyalkanoates
Polymer degradation and stability 242, 111605 - (2025) [10.1016/j.polymdegradstab.2025.111605]
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Contribution to a book
Optogenetics Methods and Protocols
[Ebook] Optogenetics : Methods and Protocols / Baumschlager, Armin 1st ed. 2025, New York, NY : Springer US, 2025,
New York, NY : Springer US : 1st ed. 2025, 1 Online-Ressource(XII, 256 p. 63 illus., 57 illus. in color. (2025) [10.1007/978-1-0716-4047-0]
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Journal Article
Measuring adsorption equilibria: The determination of the maximum binding capacity depends strongly on the method of resin preparation
Journal of chromatography 1762, 466421 - (2025) [10.1016/j.chroma.2025.466421]
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Master Thesis
The influence of Bacteriophages on Plant and Animal Microbiomes
147 pp. (2025) = Masterarbeit, HHU Düsseldorf, 2025
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Bachelor Thesis
Optimisation of (R)-3-hydroxy-phenylacetylcarbinol synthesis using pyruvate decarboxylase from the Acetobacter pasteuranius (ApPDC) variants in micro aqueous reaction system (MARS) and in aqueous reaction system
73 p. (2025) = Bachelorarbeit, Hochschule Emden-Leer, 2025
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Journal Article
Corynebacterium glutamicum: vom Umami-Geschmack zur Bioökonomie
Biospektrum 31(1), 14 - 17 (2025) [10.1007/s12268-025-2366-3]
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Master Thesis
Implementation and Characterization of High-Throughput Bioprocess Automation Analysiswith a Growth Profiler
128 p. (2025) = Masterarbeit, TU München, 2025
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Journal Article
Biosurfactant biosynthesis by Alcanivorax borkumensis and its role in oil biodegradation
Nature chemical biology 21(10), 1631 - 1641 (2025) [10.1038/s41589-025-01908-1]
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Journal Article
Upcycling of polyamides through chemical hydrolysis and engineered Pseudomonas putida
Nature microbiology 10(3), 667 - 680 (2025) [10.1038/s41564-025-01929-5]
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Bachelor Thesis
Klonierungen und Untersuchungen zur funktionalen Expression des L-Arabinose-Transporters AraE aus E. coli sowie zur Erhöhung der Aktivität der membrangebundenen Glukose-Dehydrogenase im Essigsäurebakterium Gluconobacter oxydans für die Bioprozessentwicklung
67 pp. (2025) = Bachelorarbeit, HS Hamm-Lippstadt, 2025
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Patent
Matrix-vermittelte Beschichtung von Zielorganismen mit Bioeffektoren
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Journal Article
Environmental and molecular noise buffering by the cyanobacterial clock in individual cells
Nature Communications 16(1), 3566 (2025) [10.1038/s41467-025-58169-8]
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Book/Dissertation / PhD Thesis
Exploring the process window for production of itaconic, 2 hydroxyparaconic, and itatartaric acid with engineered Ustilago strains
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 293, x, 145 (2025) [10.34734/FZJ-2024-06042] = Dissertation, Düsseldorf, 2024
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Journal Article
High-Performance C++ and Julia solvers in CADET for weakly and strongly coupled continuous chromatography problems
Computers & chemical engineering 202, 109295 - (2025) [10.1016/j.compchemeng.2025.109295]
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Journal Article
CADET-Julia: Efficient and versatile, open-source simulator for batch chromatography in Julia
Computers & chemical engineering 192, 108913 - (2025) [10.1016/j.compchemeng.2024.108913]
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Journal Article
EAP4EMSIG – enhancing event-driven microscopy for microfluidic single-cell analysis
Automatisierungstechnik 73(10), 808 - 823 (2025) [10.1515/auto-2025-0018]
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Journal Article
CRISPR/dCas-mediated counter-silencing - Reprogramming dCas proteins into antagonists of xenogeneic silencers
mBio 16(7), 1-23 (2025) [10.1128/mbio.00382-25]
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Journal Article
Resolution of physics and deep learning-based protein engineering filters: A case study with a lipase for industrial substrate hydrolysis
PLOS ONE 20(9), e0332409 - (2025) [10.1371/journal.pone.0332409]
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Master Thesis
Chassis engineering of Pseudomonas taiwanensis for enhanced production of hydrophobic aromatics
53 pp. (2025) = Masterarbeit, TH Mannheim, 2025
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Journal Article
Influence of ionic liquids on enzymatic asymmetric carboligations
Computational and structural biotechnology journal 27, 4212 - 4225 (2025) [10.1016/j.csbj.2025.09.029]
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Bachelor Thesis
Optimization of media components for peroxidase production in Komagataella Phaffii using microscale cultivation
87 p. (2025) = Bachelorarbeit, Rhein-Waal Hochschule Kleve, 2025
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Journal Article
Re‐engineering a transferase scaffold for indole C3 methylation in diketopiperazines
Protein science 34(9), e70254 (2025) [10.1002/pro.70254]
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Journal Article
Characterization of a C-methyltransferase from Streptomyces griseoviridis – crystal structure, mechanism, and substrate scope
Chemical science 16(10), 4519 - 4527 (2025) [10.1039/D4SC07300B]
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Journal Article
From molasses to purified α-ketoglutarate with engineered Corynebacterium glutamicum
Bioresource technology 416, 131803 - (2025) [10.1016/j.biortech.2024.131803]
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Contribution to a conference proceedings/Journal Article
Combining Knowledge About Metabolic Networks and Single-Cell Data with Maximum Entropy
MaxEnt 2024, Meeting location,
Physical sciences forum 12(1), 3 (2025) [10.3390/psf2025012003]
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Contribution to a book
Digitalisierung und Bioprozessierung: Aussichten und Herausforderungen
Digitale Zwillinge / Herwig, Christoph (Editor) ; Cham : Springer Nature Switzerland, 2025, Chapter 3 ; ISBN: 978-3-031-75697-9 ; doi:10.1007/978-3-031-75698-6
Cham : Springer Nature Switzerland 63-76 (2025) [10.1007/978-3-031-75698-6_3]
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Master Thesis
Bioprocess optimization of heterologous procuction of antimicrobial peptide Lysostaphin with Corynebacterium glutamicum
91 p. (2025) = Masterarbeit, Universität Bonn, 2025
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Master Thesis
Integration of biological degradation processes into a multi-component adsorption model for simulating granular activated carbon filters in wastewater treatment
33 p. (2025) = Masterarbeit, RWTH Aachen, 2025
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Master Thesis
Studies on the functional expression of the Larabinose transporter AraE from E. coli in the acetic acid bacterium Gluconobacter oxydans for establishing light-controlled gene expression using the L-arabinose-inducible AraC-ParaBAD system from E. coli
67 pp. (2025) = Masterarbeit, HS Ansbach, 2025
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Contribution to a conference proceedings/Journal Article
Trans-Dimensional Diffusive Nested Sampling for Metabolic Network Inference
MaxEnt 2024, Meeting location,
Physical sciences forum 12, 5 (2025) [10.3390/psf2025012005]
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Journal Article
Hydrophobic interaction chromatography (HIC) isotherm incorporating salt-dependent water activity enhances model-based analysis of protein elution profiles
Journal of chromatography 1756, 466095 - (2025) [10.1016/j.chroma.2025.466095]
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Master Thesis
Matrix Hit- and Run for Sampling Convex Polytopes and its GPU implementation
79 p. (2025) = Masterarbeit, Friedrich-Alexander-Universität Erlangen-Nürnberg, 2025
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Dissertation / PhD Thesis
Structuring Spatiotemporal Oxygen Environments for Microbial Single-Cell Analysis in Microfluidics
155 p. (2025) = Dissertation, RWTH Aachen, 2025
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Journal Article
Unveiling microbial single-cell growth dynamics under rapid periodic oxygen oscillations
Lab on a chip 25(9), 2234 - 2246 (2025) [10.1039/D5LC00065C]
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Journal Article
Creating Rapid Oxygen Oscillations in Microbial Single-cell Growth Analysis using a Microfluidic Double-layer Device
JoVE science education 0(221), 68697 (2025) [10.3791/68697]
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Master Thesis
Analyzing optochemical expression control systems in Gluconobacter oxydans on a single-cell level
101 p. (2025) = Masterarbeit, TU Berlin, 2025
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Master Thesis
Development of a Next-Generation Screening Method for Microplastic-Binding Adhesion Peptides using LC-MS/MS
75 p. (2025) = Masterarbeit, RWTH Aachen, 2025
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Master Thesis
Automatisierte Konstruktion einer Sekretionsstammbibliothek für die Produktion von Adhäsionsvermittlern zur Mikroplastikdetektion
148 p. (2025) = Masterarbeit, TU Berlin, 2025
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Journal Article
Creating Rapid Oxygen Oscillations in Microbial Single-cell Growth Analysis using Microfluidic Double-layer Device
JoVE / Video journal 0, 0-0 (2025)
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Journal Article
Molecular methods for high-throughput, multiplexed, and automated genome editing in prokaryotes and eukaryotes
Current opinion in biotechnology 96, 103381 - (2025) [10.1016/j.copbio.2025.103381]
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Master Thesis
Studies on the functional expression of the L-rhamnose transporter RhaT from E. coli in the acetic acid bacterium Gluconobacter oxydans for establishing light-controlled gene expression using the L-rhamnose inducible RhaS-PrhaBAD system from E. coli
85 pp. (2025) = Masterarbeit, HS Ansbach, 2025
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Journal Article
Genome‐Wide Analysis of DtxR and HrrA Regulons Reveals Novel Targets and a High Level of Interconnectivity Between Iron and Heme Regulatory Networks in Corynebacterium glutamicum
Molecular microbiology 124(2), 115-130 (2025) [10.1111/mmi.15376]
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Dissertation / PhD Thesis
Modeling and Analysis of Tracer Transport Dynamics in Plants
178 p. (2025) = Dissertation, RWTH Aachen, 2025
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Journal Article
Analyzing time activity curves from spatio-temporal tracer data to determine tracer transport velocity in plants
Mathematical biosciences 383, 109430 - (2025) [10.1016/j.mbs.2025.109430]
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Master Thesis
MoClo-based CRISPR/Cas12a workflows for standardized genomic integrations in Corynebacterium glutamicum
77 pp. (2025) = Masterarbeit, RWTH Aachen, 2025
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Book/Dissertation / PhD Thesis
Tolerance engineering of Pseudomonas for the efficient conversion and production of aldehydes
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 292, XVI, 185 (2025) [10.34734/FZJ-2024-07180] = Dissertation, Düsseldorf, 2024
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Dissertation / PhD Thesis
Enforced alteration of sugar uptake and metabolism in Corynebacterium glutamicum and application for the production of the natural low-calorie sweetener D-allulose
204 pp. (2025) = Dissertation, HHU Düsseldorf, 2025
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Journal Article
CADET-Core 5.0: High-Performance Solver for Advanced Biotechnology Process Modeling
The journal of open source software 10(111), 7881 - (2025) [10.21105/joss.07881]
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Journal Article
Exploring biotechnology for plastic recycling, degradation and upcycling for a sustainable future
Biotechnology advances 81, 108544 - (2025) [10.1016/j.biotechadv.2025.108544]
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Journal Article
Engineering of Corynebacterium glutamicum for the synthesis of aromatic compounds
Applied microbiology and biotechnology 109(1), 132 (2025) [10.1007/s00253-025-13520-3]
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Master Thesis
Regulation of lysis-lysogeny decision in Corynebacterium glutamicum ATCC 13032 harboring the CyranoPS prophage
95 pp. (2025) = Masterarbeit, HHU Düsseldorf, 2025
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Journal Article
Advancing regulatory dialogue: In silico models for improved vaccine biomanufacturing - an expert meeting report
Vaccine 56, 127170 - (2025) [10.1016/j.vaccine.2025.127170]
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Journal Article
Asymmetric synthesis of C–N axially chiral carbazoles via axial-to-axial chirality transfer
Organic & Biomolecular Chemistry 23(20), 4888-4892 (2025)
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Journal Article
Asymmetric synthesis of C–N axially chiral carbazoles via axial-to-axial chirality transfer
Organic & biomolecular chemistry 23(20), 4888 - 4892 (2025) [10.1039/D5OB00587F]
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Journal Article
Enzymatic asymmetric synthesis of all stereoisomers of aliphatic, vicinal diols in conventional and non‐conventional media
Advanced synthesis & catalysis 367(8), e202401143 (2025) [10.1002/adsc.202401143]
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Journal Article
Combination of Bio‐ and Organometallic Catalysis for the Synthesis of Dioxolanes in Organic Solvents
ChemCatChem 17(6), e202401836 (2025) [10.1002/cctc.202401836]
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Dissertation / PhD Thesis
Integration of adaptive enzymatic one- and multistep synthesis in the sustainable production of bio-fuels and chiral fine chemicals
207 pp. (2025) = Dissertation, RWTH Aachen, 2025
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Master Thesis
Reversible and Non-Reversible Parallel Tempering Methods for Efficient Polytope Sampling
52 p. (2025) = Masterarbeit, RWTH Aachen, 2025
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Bachelor Thesis
Data analysis of circadian clock mutants cultivated in a microfluidic system
56 p. (2025) = Bachelorarbeit, Heinrich Heine Universität Düsseldorf, 2025
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Journal Article
Engineering of 1,4‐Butanediol and Adipic Acid Metabolism in Pseudomonas taiwanensis for Upcycling to Aromatic Compounds
Microbial biotechnology 18(8), e70205 (2025) [10.1111/1751-7915.70205]
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Journal Article
Characterisation and Harnessing of 5‐Hydroxymethylfurfural Metabolism in Pseudomonas umsongensis GO16 for the Production of 2,5‐Furandicarboxylic Acid
Microbial biotechnology 18(5), e70159 (2025) [10.1111/1751-7915.70159]
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Contribution to a conference proceedings/Contribution to a book
How To Make Your Cell Tracker Say "I dunno!"
Proceedings of the IEEE/CVF International Conference on Computer Vision (ICCV)
International Conference on Computer Vision, ICCV 2025, HonoluluHonolulu, USA, 19 Oct 2025 - 23 Oct 2025
6914-6923 (2025)
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Master Thesis
Optimizing the biotechnological production process for erythritol with Ustilago yeast
110 pp. (2025) = Masterarbeit, FH Aachen, 2025
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Book/Dissertation / PhD Thesis
Elucidation of anti-viral strategies in Streptomyces
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 298, xii, 148 (2025) [10.34734/FZJ-2025-02793] = Dissertation, Düsseldorf, 2025
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Journal Article
Two-dimensional general rate model with particle size distribution in CADET calibrated with high-definition CFD simulated intra-column data
Separation and purification technology 379, 134409 - (2025) [10.1016/j.seppur.2025.134409]
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Dissertation / PhD Thesis
Advances and Applications in High-Definition Simulation of Packed Bed Liquid Chromatography
124 p. (2025) = Dissertation, RWTH Aachen, 2025
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Master Thesis
Application of automated methods to optimise the secretion to two bifunctional proteins in C. glutamicum using different signal peptides
104 p. (2025) = Masterarbeit, FH Jülich, Campus Jülich, 2025
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Journal Article
Rapid exometabolome footprinting combined with multivariate statistics: A powerful tool for bioprocess optimization
Engineering in life sciences 25(2), 2300222 (2025) [10.1002/elsc.202300222]
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Journal Article
Insights into the morphology-productivity relationship of filamentous fungi through small-scale cultivation and automated microscopy of Thermothelomyces thermophilus
Biotechnology progress 41(3), e3528 (2025) [10.1002/btpr.3528]
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Journal Article
SIGHT—A System for Solvent‐Tight Incubation and Growth Monitoring in High Throughput
Engineering in life sciences 25(2), e202400037 (2025) [10.1002/elsc.202400037]
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Book/Dissertation / PhD Thesis
Metabolic engineering of Pseudomonas taiwanensis for the improved production of styrene
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 297, XII, 147 (2025) [10.34734/FZJ-2025-03157] = Dissertation, Düsseldorf, 2025
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Bachelor Thesis
The Influence of deleted prophage regions in Pseudomonas production strains on phage susceptibility
48 pp. (2025) = Bachelorarbeit, HHU Düsseldorf, 2025
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Journal Article
Inhibitory effect of plant flavonoid cyanidin on oral microbial biofilm
Microbiology spectrum 13(6), e02848-24 (2025) [10.1128/spectrum.02848-24]
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Master Thesis
Leveraging mechanistic modeling of the Shikimate pathway in Corynebacterium glutamicum to support rational strain construction
69 pp. (2025) = Masterarbeit, RWTH Aachen, 2025
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Dissertation / PhD Thesis
Geometry-aware Image Analysis for Microfluidic Live-cell Experimentation
135 p. (2025) = Dissertation, RWTH Aachen, 2025
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Journal Article
Chemoenzymatic Total Synthesis of Lansai B
Chemistry - a European journal 31(26), e202500740 (2025) [10.1002/chem.202500740]
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Master Thesis
Metabolic engineering of Pseudomonas taiwanensis for sustainable bio-production of 2-phenylethyl acetate
75 pp. (2025) = Masterarbeit, Heinrich-Heine University Düsseldorf, 2025
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Journal Article
Engineered Passive Glucose Uptake in Pseudomonas taiwanensis VLB120 Increases Resource Efficiency for Bioproduction
Microbial biotechnology 18(1), e70095 (2025) [10.1111/1751-7915.70095]
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Master Thesis
Optimal Experimental Design in Isotopically Nonstationary Metabolic Flux Analysis
88 p. (2025) = Masterarbeit, Karlsruher Institute of Technology - KIT, 2
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Journal Article
PyUAT: An open-source Python framework for uncertainty-aware, efficient, and scalable model-driven cell tracking
PLOS ONE 20(12), e0337110 - (2025) [10.1371/journal.pone.0337110]
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Dissertation / PhD Thesis
Quantitative single-cell analysis using deep learning based smart live-cell microscopy
195 p. (2025) = Dissertation, RWTH Aachen, 2025
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Contribution to a conference proceedings/Contribution to a book
Tracking One-in-a-Million: Large-Scale Benchmark for Microbial Single-Cell Tracking with Experiment-Aware Robustness Metrics
Computer Vision – ECCV 2024 Workshops / Del Bue, Alessio (Editor) ; Cham : Springer Nature Switzerland, 2025, Chapter 20 ; ISSN: 0302-9743=1611-3349 ; ISBN: 978-3-031-91720-2=978-3-031-91721-9 ; doi:10.1007/978-3-031-91721-9
ECCV 2024, MilanoMilano, Italy, 29 Sep 2024 - 4 Oct 2024
Cham : Springer Nature Switzerland, Lecture Notes in Computer Science 15638, 318 - 334 (2025) [10.1007/978-3-031-91721-9_20]
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Journal Article
Avoiding Replicates in Biocatalysis Experiments: Machine Learning for Enzyme Cascade Optimization
ChemCatChem 17(1), e202400777 (2025) [10.1002/cctc.202400777]
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Journal Article
Jahresrückblick Organische Chemie: Naturstoff(total)synthese
Nachr. Chem. Tech. Lab. 73(3), 61-63 (2025)
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Journal Article
A Sustainable Method for Potato Side Stream Valorisation to Obtain Steroidal Glycoalkaloids within a Bioeconomy Approach
Green chemistry 27(45), 14683-14694 (2025) [10.1039/D5GC03072B]
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Journal Article
13CFLUX — Third-generation high-performance engine for isotopically (non)stationary 13C metabolic flux analysis
Bioinformatics 41(12), btaf630 (2025) [10.1093/bioinformatics/btaf630]
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Master Thesis
Exploring the catalyttic potential of the carboxylic acid reductase from Neurospora crassa for the enzymtic reduction of formic acid to formaldehyde
82 p. (2025) = Masterarbeit, FH Aachen, Campus Jülich, 2025
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Bachelor Thesis
Einfluss der Eisenverfügbarkeit auf die Infektiosität von Bakteriophagen bei E. coli
57 pp. (2025) = Bachelorarbeit, HHU Düsseldorf, 2025
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Journal Article
Quantifying data needs in surrogate modeling for flow fields in two-dimensional stirred tanks with physics-informed neural networks
Physics of fluids 37(11), 117112 (2025) [10.1063/5.0291054]
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Master Thesis
Comparative cultivation of Cyanidioschyzon merolae and Galdieria sulphuraria, isolation and characterisation of phycobiliproteins, carotenoids and fatty acids for the evaluation of an integrated biorefinery concept
87 pp. (2025) = Masterarbeit, FH Jülich, 2025
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Journal Article
Functionalized in Triplicate: A Ring‐By‐Ring Approach to Tailored Prodiginine Derivatives for Site‐Specific Conjugation Through Click Chemistry
Chemistry - a European journal 31(43), e202502066 (2025) [10.1002/chem.202502066]
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Journal Article
Building trust in automated experimentation: uncertainty quantification in the era of high-throughput biolabs
Current opinion in biotechnology 96, 103382 - (2025) [10.1016/j.copbio.2025.103382]
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A microfluidic system for the cultivation of cyanobacteria with precise light intensity and CO 2 control: enabling growth data acquisition at single-cell resolution
Lab on a chip 25(3), 319-329 (2025) [10.1039/D4LC00567H]
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Master Thesis
Automation of a CRISPR/Cas12a-mediated genome editing system in Corynebacterium glutamicum
96 p. (2025) = Masterarbeit, RWTH Aachen, 2025
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Master Thesis
Massivelyparallel high-definition simulation of packed-bed chromatography in laterally unconfined compartments
62 p. (2025) = Masterarbeit, RWTH Aachen, 2025
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Solving crystallization/precipitation population balance models in CADET, part II: Size-based Smoluchowski coagulation and fragmentation equations in batch and continuous modes
Computers & chemical engineering 192, 108860 - (2025) [10.1016/j.compchemeng.2024.108860]
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Chemoenzymatic C,C-Bond Forming Cascades by Cryptic Vanadium Haloperoxidase Catalyzed Bromination
Organic letters 27(1), 159 - 164 (2025) [10.1021/acs.orglett.4c04108]
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ALE reveals a surprising link between [Fe-S] cluster formation, tryptophan biosynthesis and the potential regulatory protein TrpP in Corynebacterium glutamicum
BMC microbiology 25(1), 214 (2025) [10.1186/s12866-025-03939-z]
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