Publications 2025

Master Thesis Andree, A.FZJ*
Microfluidic Platform for the Study of Stable Co-Cultures: Phototrophic and Heterotrophic Microorganisms in Sucrose-Driven Carbon Exchange
95 p. (2025)2025 = Masterarbeit, Universität Bonn, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Bott, M. (Corresponding author)FZJ* ; Wendisch, V. F.
Corynebacterium glutamicum: vom Umami-Geschmack zur Bioökonomie
Biospektrum 31(1), 14 - 17 (2025) [10.1007/s12268-025-2366-3]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article de Witt, J. ; Luthe, T.FZJ* ; Wiechert, J.FZJ* ; Jensen, K. ; Polen, T.FZJ* ; Wirtz, A.FZJ* ; Thies, S.FZJ* ; Frunzke, J.FZJ* ; Wynands, B.FZJ* ; Wierckx, N.FZJ*
Upcycling of polyamides through chemical hydrolysis and engineered Pseudomonas putida
Nature microbiology 10(3), 667 - 680 (2025) [10.1038/s41564-025-01929-5]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Patent Erdrich, S.FZJ* ; Arsova, B.FZJ* ; Frunzke, J.FZJ* ; Schurr, U.FZJ*
Matrix-vermittelte Beschichtung von Zielorganismen mit Bioeffektoren
Fulltext BibTeX | EndNote: XML, Text | RIS

Journal Article Eremina, A. ; Schwall, C. ; Saez, T. ; Witting, L.FZJ* ; Kohlheyer, D.FZJ* ; Martins, B. M. C. ; Thomas, P. ; Locke, J. C. W. (Corresponding author)
Environmental and molecular noise buffering by the cyanobacterial clock in individual cells
Nature Communications 16(1), 3566 (2025) [10.1038/s41467-025-58169-8]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Book/Dissertation / PhD Thesis Ernst, P. (Corresponding author)FZJ*
Exploring the process window for production of itaconic, 2 hydroxyparaconic, and itatartaric acid with engineered Ustilago strains
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 293, x, 145 (2025) [10.34734/FZJ-2024-06042]2025 = Dissertation, Düsseldorf, 2024 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Frandsen, J. ; Breuer, J. M.FZJ* ; Schmölder, J.FZJ* ; Huusom, J. K. ; Gernaey, K. V. ; Abildskov, J. ; von Lieres, E. (Corresponding author)FZJ*
CADET-Julia: Efficient and versatile, open-source simulator for batch chromatography in Julia
Computers & chemical engineering 192, 108913 - (2025) [10.1016/j.compchemeng.2024.108913]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Frunzke, J.FZJ* ; Wiechert, J.FZJ* ; Badia Roigé, B.FZJ* ; Dohmen-Olma, D.FZJ* ; Hindra ; Zhang, X. ; Stella, R. G. ; Elliot, M. A.
CRISPR/dCas-mediated counter-silencing - Reprogramming dCas proteins into antagonists of xenogeneic silencers
mBio 16(7), 1-23 (2025) [10.1128/mbio.00382-25]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Halle, L.FZJ* ; Höppner, D.FZJ* ; Doser, M.FZJ* ; Brüsseler, C. ; Gätgens, J.FZJ* ; Conen, N. ; Jupke, A.FZJ* ; Marienhagen, J.FZJ* ; Noack, S. (Corresponding author)FZJ*
From molasses to purified α-ketoglutarate with engineered Corynebacterium glutamicum
Bioresource technology 416, 131803 - (2025) [10.1016/j.biortech.2024.131803]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Master Thesis Hoffzimmer, A.FZJ*
Bioprocess optimization of heterologous procuction of antimicrobial peptide Lysostaphin with Corynebacterium glutamicum
91 p. (2025)2025 = Masterarbeit, Universität Bonn, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Jäpel, R. (Corresponding author)FZJ* ; Knödler, M. ; von Lieres, E.FZJ* ; Buyel, J. F. (Corresponding author)
Hydrophobic interaction chromatography (HIC) isotherm incorporating salt-dependent water activity enhances model-based analysis of protein elution profiles
Journal of chromatography 1756, 466095 - (2025) [10.1016/j.chroma.2025.466095]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Dissertation / PhD Thesis Kasahara, K.FZJ*
Structuring Spatiotemporal Oxygen Environments for Microbial Single-Cell Analysis in Microfluidics
155 p. (2025)2025 = Dissertation, RWTH Aachen, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Kasahara, K.FZJ* ; Seiffarth, J. ; Stute, B.FZJ* ; von Lieres, E.FZJ* ; Drepper, T.FZJ* ; Nöh, K.FZJ* ; Kohlheyer, D. (Corresponding author)FZJ*
Unveiling microbial single-cell growth dynamics under rapid periodic oxygen oscillations
Lab on a chip 25(9), 2234 - 2246 (2025) [10.1039/D5LC00065C]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Master Thesis Kayserling, A. (Corresponding author)FZJ*
Analyzing optochemical expression control systems in Gluconobacter oxydans on a single-cell level
101 p. (2025)2025 = Masterarbeit, TU Berlin, 2025 BibTeX | EndNote: XML, Text | RIS

Master Thesis Keilen, K.FZJ*
Development of a Next-Generation Screening Method for Microplastic-Binding Adhesion Peptides using LC-MS/MS
75 p. (2025)2025 = Masterarbeit, RWTH Aachen, 2025 BibTeX | EndNote: XML, Text | RIS

Master Thesis Kern, B.FZJ*
Automatisierte Konstruktion einer Sekretionsstammbibliothek für die Produktion von Adhäsionsvermittlern zur Mikroplastikdetektion
148 p. (2025)2025 = Masterarbeit, TU Berlin, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Kohlheyer, D.FZJ*
Creating Rapid Oxygen Oscillations in Microbial Single-cell Growth Analysis using Microfluidic Double-layer Device
JoVE / Video journal 0, 0-0 (2025)2025 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Krüger, A.FZJ* ; Weber, U.FZJ* ; Frunzke, J. (Corresponding author)FZJ*
Genome‐Wide Analysis of DtxR and HrrA Regulons Reveals Novel Targets and a High Level of Interconnectivity Between Iron and Heme Regulatory Networks in Corynebacterium glutamicum
Molecular microbiology 124(2), 115-130 (2025) [10.1111/mmi.15376]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Lanzrath, H.FZJ* ; von Lieres, E.FZJ* ; Metzner, R.FZJ* ; Huber, G. (Corresponding author)FZJ*
Analyzing time activity curves from spatio-temporal tracer data to determine tracer transport velocity in plants
Mathematical biosciences 383, 109430 - (2025) [10.1016/j.mbs.2025.109430]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Book/Dissertation / PhD Thesis Lechtenberg, T.FZJ*
Tolerance engineering of Pseudomonas for the efficient conversion and production of aldehydes
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 292, XVI, 185 (2025) [10.34734/FZJ-2024-07180]2025 = Dissertation, Düsseldorf, 2024 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Leweke, S.FZJ* ; Breuer, J.FZJ* ; Schmölder, J.FZJ* ; Jäpel, R.FZJ* ; Lanzrath, H.FZJ* ; Rao, J.FZJ* ; Hassan, J.FZJ* ; Zhang, W. ; Berger, A.FZJ* ; Heymann, W. ; von Lieres, E.FZJ*
CADET-Core 5.0: High-Performance Solver for Advanced Biotechnology Process Modeling
The journal of open source software 10(111), 7881 - (2025) [10.21105/joss.07881]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Liu, X. ; Park, H. ; Ackermann, Y.FZJ* ; Avérous, L. ; Ballerstedt, H. ; Besenmatter, W. ; Blázquez, B. ; Bornscheuer, U. T. ; Branson, Y. ; Casey, W. ; de Lorenzo, V. ; Dong, W. ; Floehr, T. ; Godoy, M. S. ; Ji, Y. ; Jupke, A.FZJ* ; Klankermayer, J. ; León, D. S. ; Liu, L. ; Liu, X. ; Liu, Y. ; Manoli, M. T. ; Martínez-García, E. ; Narancic, T. ; Nogales, J. ; O'Connor, K. ; Osterthun, O. ; Perrin, R. ; Prieto, M. A. ; Pollet, E. ; Sarbu, A. ; Schwaneberg, U. ; Su, H. ; Tang, Z. ; Tiso, T. ; Wang, Z. ; Wei, R. ; Welsing, G. ; Wierckx, N.FZJ* ; Wolter, B. ; Xiao, G. ; Xing, J. ; Zhao, Y.FZJ* ; Zhou, J. ; Tan, T. ; Blank, L. M. ; Jiang, M. ; Chen, G.-Q.
Exploring biotechnology for plastic recycling, degradation and upcycling for a sustainable future
Biotechnology advances 81, 108544 - (2025) [10.1016/j.biotechadv.2025.108544]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Marienhagen, J. (Corresponding author)FZJ*
Engineering of Corynebacterium glutamicum for the synthesis of aromatic compounds
Applied microbiology and biotechnology 109(1), 132 (2025) [10.1007/s00253-025-13520-3]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Meln, I. (Corresponding author) ; Van Molle, W. ; Vélez, M. P. ; Abrahamsen, G. ; Brusselmans, K. ; Calvosa, E. ; Cardillo, A. G. ; Clénet, D. ; Forestieri, C. ; Gernaey, K. V. ; Hoefnagel, M. ; Jorgensen, J. B. ; Lebrun, P. ; Natalis, L. ; Nilsson, B. ; Öppling, V. ; Pollinger, J. C. ; Rayat, A. C. M. E. ; Reem, D. ; Rubbrecht, M. ; Schmölder, J.FZJ* ; Schofield, T. ; Smith, D. ; Timmins, S. ; von Lieres, E.FZJ* ; Welin, M. ; Bracewell, D. G.
Advancing regulatory dialogue: In silico models for improved vaccine biomanufacturing - an expert meeting report
Vaccine 56, 127170 - (2025) [10.1016/j.vaccine.2025.127170]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Myllek, S. ; Lencer, P.FZJ* ; Klischan, M. K. T. ; Henssen, B.FZJ* ; Neudecker, P.FZJ* ; Breugst, M. ; Pietruszka, J. (Corresponding author)FZJ*
Asymmetric synthesis of C–N axially chiral carbazoles via axial-to-axial chirality transfer
Organic & biomolecular chemistry 23(20), 4888 - 4892 (2025) [10.1039/D5OB00587F]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Nicolas, M.FZJ* ; Küsters-Spöring, J.-D. ; Aufderheide, C. ; Traving, H. ; Kipp, C. ; Pfennig, V. ; Bolm, C. ; Siegert, P. ; Rother, D. (Corresponding author)FZJ*
Enzymatic asymmetric synthesis of all stereoisomers of aliphatic, vicinal diols in conventional and non‐conventional media
Advanced synthesis & catalysis 367(8), e202401143 (2025) [10.1002/adsc.202401143]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Nicolas, M.FZJ* ; Gaelings, N. ; Wiesenthal, J. ; von Westarp, W. G. ; Pehlivanlar, B. ; Pischinger, S. ; Jupke, A.FZJ* ; Klankermayer, J. ; Rother, D.FZJ*
Combination of Bio‐ and Organometallic Catalysis for the Synthesis of Dioxolanes in Organic Solvents
ChemCatChem 17(6), e202401836 (2025) [10.1002/cctc.202401836]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Dissertation / PhD Thesis Nicolas, M.FZJ*
Integration of adaptive enzymatic one- and multistep synthesis in the sustainable production of bio-fuels and chiral fine chemicals
207 pp. (2025)2025 = Dissertation, RWTH Aachen, 2025 BibTeX | EndNote: XML, Text | RIS

Bachelor Thesis Nohr, J. (Corresponding author)FZJ*
Data analysis of circadian clock mutants cultivated in a microfluidic system
56 p. (2025)2025 = Bachelorarbeit, Heinrich Heine Universität Düsseldorf, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Orimaco, R.Extern* ; Donnelly, P. ; Sexton, S. ; McLoughlin, A. ; Kelly, S. ; O'Connor, K. E. ; Wierckx, N.FZJ* ; Narančić, T. (Corresponding author)
Characterisation and Harnessing of 5‐Hydroxymethylfurfural Metabolism in Pseudomonas umsongensis GO16 for the Production of 2,5‐Furandicarboxylic Acid
Microbial biotechnology 18(5), e70159 (2025) [10.1111/1751-7915.70159]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Book/Dissertation / PhD Thesis Rackow, B.FZJ*
Elucidation of anti-viral strategies in Streptomyces
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 298, xii, 148 (2025) [10.34734/FZJ-2025-02793]2025 = Dissertation, Düsseldorf, 2025 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Master Thesis Recker, V. (Corresponding author)FZJ*
Application of automated methods to optimise the secretion to two bifunctional proteins in C. glutamicum using different signal peptides
104 p. (2025)2025 = Masterarbeit, FH Jülich, Campus Jülich, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Reiter, A. ; Wesseling, L. ; Wiechert, W.FZJ* ; Oldiges, M. (Corresponding author)FZJ*
Rapid exometabolome footprinting combined with multivariate statistics: A powerful tool for bioprocess optimization
Engineering in life sciences 25(2), 2300222 (2025) [10.1002/elsc.202300222]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Rohr, K.FZJ* ; Geinitz, B.FZJ* ; Seiffarth, J.FZJ* ; Anbarani, A. ; Bernauer, S. ; Moch, M.FZJ* ; Tenhaef, J.FZJ* ; Wiechert, W.FZJ* ; Nöh, K.FZJ* ; Oldiges, M. (Corresponding author)FZJ*
Insights into the morphology-productivity relationship of filamentous fungi through small-scale cultivation and automated microscopy of Thermothelomyces thermophilus
Biotechnology progress 41(3), e3528 (2025) [10.1002/btpr.3528]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Rönitz, J.FZJ* ; Herrmann, F.FZJ* ; Wynands, B.FZJ* ; Polen, T.FZJ* ; Wierckx, N. (Corresponding author)FZJ*
SIGHT—A System for Solvent‐Tight Incubation and Growth Monitoring in High Throughput
Engineering in life sciences 25(2), e202400037 (2025) [10.1002/elsc.202400037]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Book/Dissertation / PhD Thesis Rönitz, J.FZJ*
Metabolic engineering of Pseudomonas taiwanensis for the improved production of styrene
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 297, XII, 147 (2025) [10.34734/FZJ-2025-03157]2025 = Dissertation, Düsseldorf, 2025 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Dissertation / PhD Thesis Ruzaeva, K.FZJ*
Geometry-aware Image Analysis for Microfluidic Live-cell Experimentation
135 p. (2025)2025 = Dissertation, RWTH Aachen, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Schatton, M.FZJ* ; Haase, M.FZJ* ; Tenhaef, J.FZJ* ; Gronkowsky, C.FZJ* ; Noack, S.FZJ* ; Pietruszka, J. (Corresponding author)FZJ*
Chemoenzymatic Total Synthesis of Lansai B
Chemistry - a European journal 31(26), e202500740 (2025) [10.1002/chem.202500740]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Schwanemann, T. ; Krink, N. ; Nikel, P. I. ; Wynands, B.FZJ* ; Wierckx, N. (Corresponding author)FZJ*
Engineered Passive Glucose Uptake in Pseudomonas taiwanensis VLB120 Increases Resource Efficiency for Bioproduction
Microbial biotechnology 18(1), e70095 (2025) [10.1111/1751-7915.70095]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Siedentop, R. (Corresponding author) ; Siska, M. (Corresponding author)FZJ* ; Hermes, J. ; Lütz, S. ; von Lieres, E.FZJ* ; Rosenthal, K.
Avoiding Replicates in Biocatalysis Experiments: Machine Learning for Enzyme Cascade Optimization
ChemCatChem 17(1), e202400777 (2025) [10.1002/cctc.202400777]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Witting, L.FZJ* ; Seiffarth, J. ; Stute, B.FZJ* ; Schulze, T. ; Hofer, J. M. ; Nöh, K.FZJ* ; Eisenhut, M. ; Weber, A. P. M. ; von Lieres, E.FZJ* ; Kohlheyer, D. (Corresponding author)FZJ*
A microfluidic system for the cultivation of cyanobacteria with precise light intensity and CO 2 control: enabling growth data acquisition at single-cell resolution
Lab on a chip 25(3), 319-329 (2025) [10.1039/D4LC00567H]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Master Thesis Wolf, L.FZJ*
Automation of a CRISPR/Cas12a-mediated genome editing system in Corynebacterium glutamicum
96 p. (2025)2025 = Masterarbeit, RWTH Aachen, 2025 BibTeX | EndNote: XML, Text | RIS

Journal Article Zhang, W. ; Przybycien, T. ; Breuer, J. M.FZJ* ; von Lieres, E. (Corresponding author)FZJ*
Solving crystallization/precipitation population balance models in CADET, part II: Size-based Smoluchowski coagulation and fragmentation equations in batch and continuous modes
Computers & chemical engineering 192, 108860 - (2025) [10.1016/j.compchemeng.2024.108860]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Zhao, Q. ; Zhang, R. ; Döbber, J. ; Gulder, T. (Corresponding author)
Chemoenzymatic C,C-Bond Forming Cascades by Cryptic Vanadium Haloperoxidase Catalyzed Bromination
Organic letters 27(1), 159 - 164 (2025) [10.1021/acs.orglett.4c04108]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Zuchowski, R. ; Schito, S. ; Mack, C. ; Wirtz, A.FZJ* ; Bott, M.FZJ* ; Polen, T.FZJ* ; Noack, S.FZJ* ; Baumgart, M. (Corresponding author)FZJ*
ALE reveals a surprising link between [Fe-S] cluster formation, tryptophan biosynthesis and the potential regulatory protein TrpP in Corynebacterium glutamicum
BMC microbiology 25(1), 214 (2025) [10.1186/s12866-025-03939-z]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Last Modified: 18.02.2025