Publications 2025
2025
Journal Article
Disruption of ClC-3-mediated 2Cl−/H+ exchange leads to behavioural deficits and thalamic atrophy
Scientific reports 15(1), 33326 (2025) [10.1038/s41598-025-19757-2]
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Journal Article
An External, Independent Validation of an O -(2-[ 18 F]Fluoroethyl)-l-Tyrosine PET Automatic Segmentation Network on a Single-Center, Prospective Dataset of Patients with Glioblastoma
Journal of nuclear medicine 66(1), - (2025) [10.2967/jnumed.124.268925]
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Journal Article
The Status of Neuroimaging with SPECT and PET in Germany: Results from the 1st Survey on Nuclear Neuroimaging in Germany in 2023
Nuklearmedizin -, a-2566-1487 (2025) [10.1055/a-2566-1487]
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Journal Article
The Value of Multidisciplinary Neuro-oncological Tumor Boards to Increase the Accuracy of FET PET for Identifying Brain Tumor Relapse
Clinical nuclear medicine 50(4), 307 - 315 (2025) [10.1097/RLU.0000000000005634]
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Patent
Magnetresonanz-System mit transkranieller Gleichstromstimulation und Verfahren
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Abstract
JS01.3.A FULLY AUTOMATED EVALUATION OF FET PET IN BRAIN TUMOR PATIENTS - AN INTERNATIONAL, MULTICENTER STUDY
European Association of Neuro-Oncology, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.001]
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Journal Article
Nonlinear effects in magnetic resonance localized spectroscopy and images
Progress in nuclear magnetic resonance spectroscopy 146-147, 101557 - (2025) [10.1016/j.pnmrs.2025.101557]
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Journal Article
“Fill States”: PET-derived Markers of the Spatial Extent of Alzheimer Disease Pathology
Radiology 314(3), e241482 (2025) [10.1148/radiol.241482]
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Journal Article
On the use of multi-echo NODDI MRI with released intrinsic diffusivity for the assessment of tissue diffusion and relaxation properties in experimental ischaemic stroke
NeuroImage 318, 121390 - (2025) [10.1016/j.neuroimage.2025.121390]
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Journal Article
High dynamic range B1+ mapping for the evaluation of parallel transmit arrays
Magnetic resonance in medicine 93(3), 1298-1305 (2025) [10.1002/mrm.30349]
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Abstract
Early phase 18F-FET PET may help to differentiate tumor progression from treatment-related changes in glioma patients
Kongress der Deutschen Gesellschaft für Neurologie, DGN 2025, BerlinBerlin, Germany, 12 Nov 2025 - 15 Nov 2025
(2025) [10.1055/s-0045-1804440]
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Abstract
IMG-76. FET PET reveals considerable volumetric and spatial differences in tumor burden compared to conventional MRI in recurrent glioblastoma
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, SNO / WFNOS 2025, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.1155]
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Journal Article
Update to the RANO working group and EANO recommendations for the clinical use of PET imaging in gliomas
The lancet / Oncology 26(8), e436 - e447 (2025) [10.1016/S1470-2045(25)00193-7]
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Journal Article
The role of amino acid PET in the era of checkpoint inhibitors and targeted therapy for brain tumor treatment
Current opinion in neurology 10, - (2025) [10.1097/WCO.0000000000001425]
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Journal Article
Assessment of 18F-FET PET-based response in patients with gliomas using the PET RANO 1.0 criteria
Neuro-oncology advances 7(1), vdaf198 (2025) [10.1093/noajnl/vdaf198]
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Abstract
P17.06.A VORASIDENIB AS MAINTENANCE TREATMENT AFTER FIRST-LINE CHEMORADIOTHERAPY IN IDH-MUTANT GRADE 2/3 ASTROCYTOMA: STUDY PROTOCOL FOR THE PLACEBO-CONTROLLED, TRIPLE-BLIND, RANDOMIZED PHASE III STUDY EORTC-2427 (VIGOR)
European Association of Neuro-Oncology 2025, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.522]
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Abstract
CTNI-09. VORASIDENIB AS MAINTENANCE TREATMENT AFTER FIRST-LINE CHEMORADIOTHERAPY IN IDH-MUTANT GRADE 2/3 ASTROCYTOMA: STUDY PROTOCOL FOR THE PLACEBO-CONTROLLED, TRIPLE-BLIND, RANDOMIZED PHASE III STUDY EORTC-2427 (VIGOR)
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, SNO / WFNOS 2025, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.0506]
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Journal Article
Hemispheric asymmetry in high-energy phosphate consumption during sleep-deprivation is balanced by creatine
Frontiers in neuroscience 19, 1515761 (2025) [10.3389/fnins.2025.1515761]
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Contribution to a conference proceedings/Contribution to a book
XAIguiFormer: explainable artificial intelligence guided transformer for brain disorder identification
The Thirteenth International Conference on Learning Representations ICLR 2025, ICLR 2025, SingaporeSingapore, Singapore, 24 Apr 2025 - 28 Apr 2025
1-19 (2025)
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Journal Article
Shared neurobiological changes in individuals with Crohn’s disease and major depressive disorder
Communications medicine 5(1), 388 (2025) [10.1038/s43856-025-01117-w]
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Abstract
P03.15.B BOLD ASYNCHRONY MAPS FOR THE VISUALIZATION OF IDH-MUTANT GLIOMAS - A COMPARISON WITH FET PET
European Association of Neuro-Oncology 2025, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.174]
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Patent
DOPPELTRESONANTE SPULE SOWIE ARRAY VON DOPPELTRESONANTEN SPULEN UND DEREN VERWENDUNG / DOUBLE-RESONANT COIL, ARRAY OF DOUBLE-RESONANT COILS, AND USE THEREOF
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Patent
MR COIL ASSEMBLY WITH MULTIPLE DIPOLE ANTENNAS AND CONNECTION ELEMENTS WITH BLOCKING CIRCUITS
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Journal Article
Novel 1 H/ 19 F double‐tuned coil using an asymmetrical butterfly coil
Medical physics 52(7), 17890 (2025) [10.1002/mp.17890]
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Contribution to a conference proceedings
Effects of Dead Time Correction on Quantification Accuracy in Brain PET Imaging
2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD), YokohamaYokohama, Japan, 1 Nov 2025 - 8 Nov 2025
IEEE 1-1 (2025) [10.1109/NSS/MIC/RTSD57106.2025.11287723]
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Journal Article
ASNR Consensus Statement: Integrating Neuro-PET Interpretation into Neuroradiology Training and Practice
American journal of neuroradiology , ajnr.A8959 - (2025) [10.3174/ajnr.A8959]
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Journal Article
Intraretinal Electrophysiology and Resistivity Profiles of WT and RCS Rat Retina
Sensors 25(12), 3765 (2025) [10.3390/s25123765]
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Journal Article
Late emergence of pathological oscillatory activity in the retina of the Retinitis pigmentosa model RCS (Royal College of Surgeons) rat
PLOS ONE 20(5), e0324345 - (2025) [10.1371/journal.pone.0324345]
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Journal Article
Beyond fluorodeoxyglucose: Molecular imaging of cancer in precision medicine
CA 75(3), 226-242 (2025) [10.3322/caac.70007]
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Abstract
IMG-98. Metabolic response using the PET RANO 1.0 criteria following chemoradiation is associated with an increase in functional connectivity
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, SNO / WFNOS 2025, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.1177]
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Journal Article
Autoradiography of Intracerebral Tumours in the Chick Embryo Model: A Feasibility Study Using Different PET Tracers
Molecular imaging & biology 27(1), 151–162 (2025) [10.1007/s11307-025-01983-9]
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Journal Article
Brain Tumor Characterization Using Multiple MR Parameters From Multi‐Contrast EPI With Keyhole ( GE ‐ SE EPIK ) Including Oxygen Extraction Fraction: A Comparison to O‐(2‐[ 18F ]Fluoroethyl)‐L‐Tyrosine (FET) Positron Emission Tomography
Journal of magnetic resonance imaging 62(3), 721-736 (2025) [10.1002/jmri.29795]
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Journal Article
Analysis of the BraTS 2023 Intracranial Meningioma Segmentation Challenge
Melba 3(March 2025), 38 - 58 (2025) [10.59275/j.melba.2025-bea1]
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Journal Article
Borderline Findings in O -(2-[ 18 F]-Fluoroethyl)-l-Tyrosine PET of Patients with Suspected Glioma Relapse: Role in Clinical Practice
Journal of nuclear medicine 66(2), 187-193 (2025) [10.2967/jnumed.124.268768]
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Journal Article
Influence of oral protein intake on [18F]FET uptake in brain tumours
EJNMMI Research 15(1), 109 (2025) [10.1186/s13550-025-01304-9]
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Journal Article
Fast maximum likelihood positioning for a staggered layer scintillation PET detector
Physics in medicine and biology 70(17), 175018 - (2025) [10.1088/1361-6560/adf8ab]
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Contribution to a conference proceedings/Contribution to a book
The BrainPET-7T Insert for Neuroscientific Applications: Performance with and without MRI
2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD) : [Proceedings] - IEEE, 2025. - ISBN 978-1-6654-7767-3 - doi:10.1109/NSS/MIC/RTSD57106.2025.11287328
2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD), YokohamaYokohama, Japan, 1 Nov 2025 - 8 Nov 2025
IEEE 1-1 (2025) [10.1109/NSS/MIC/RTSD57106.2025.11287328]
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Patent
METHOD FOR THE POSITION AND ENERGY DETERMINATION IN SCINTILLATION DETECTORS
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Contribution to a conference proceedings
Inter-Crystal Scattering Study in a Staggered-Layer Pixelated Scintillation Detector of the BrainPET-7T
2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD), YokohamaYokohama, Japan, 1 Nov 2025 - 8 Nov 2025
IEEE 1-1 (2025) [10.1109/NSS/MIC/RTSD57106.2025.11287648]
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Journal Article
Advancements in non-invasive visualization of the immune environment in glioblastoma: A Systematic Review
Neuro-oncology advances 7(1), vdaf176 (2025) [10.1093/noajnl/vdaf176]
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Abstract
P03.22.A USE OF POSITRON EMISSION TOMOGRAPHY (PET) IN PATIENTS WITH BRAIN TUMOURS AMONG EUROPEAN ORGANISATION FOR RESEARCH AND TREATMENT OF CANCER - BRAIN TUMOUR GROUP (EORTC-BTG) SITES
European Association of Neuro-Oncology 2025, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.181]
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Abstract
IMG-82. Positron emission tomography (PET) use among European Organisation for Research and Treatment of Cancer – Brain Tumour Group (EORTC-BTG) sites – a cross-sectional survey
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, SNO / WFNOS 2025, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.1161]
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Journal Article
Availability and use of PET in patients with brain tumours – a European Organisation for Research and Treatment of Cancer - Brain Tumour Group (EORTC-BTG) survey
European journal of nuclear medicine and molecular imaging 52, 4627-4638 (2025) [10.1007/s00259-025-07366-0]
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Journal Article
Evaluation of CT and MRI Radiomics for an Early Assessment of Diffuse Axonal Injury in Patients with Traumatic Brain Injury Compared to Conventional Radiological Diagnosis
Clinical neuroradiology 35, 521-532 (2025) [10.1007/s00062-025-01507-6]
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Journal Article
The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI
Machine learning for biomedical imaging 3(June 2025), 204 - 260 (2025) [10.59275/j.melba.2025-9bd3]
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Contribution to a conference proceedings/Journal Article - Online First
Sensitivity and Count Rate Performance Studies of the BrainPET-7T Insert with Standard and Non-Standard PET Isotopes
Seminar, Meeting location, 1 Nov 2025 - 8 Nov 2025
IEEE transactions on radiation and plasma medical sciences -, - (2025) [10.1109/TRPMS.2025.3650091]
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Contribution to a conference proceedings
Timing Calibration and Count Rate Performance for the Brainpet-7T Insert
2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD), YokohamaYokohama, Japan, 1 Nov 2025 - 8 Nov 2025
IEEE 1-1 (2025) [10.1109/NSS/MIC/RTSD57106.2025.11286355]
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Journal Article
7-Tesla ultra-high field MRI of the parahippocampal cortex reveals evidence of common neurobiological mechanisms of major depressive disorder and neurotic personality traits
Translational Psychiatry 15(1), 227 (2025) [10.1038/s41398-025-03435-y]
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Journal Article
Subjective cognitive decline in individuals with isolated REM sleep behavior disorder
npj Parkinson's Disease 11(1), 287 (2025) [10.1038/s41531-025-01161-2]
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Abstract
JS03.5.A ASSESSMENT OF 18F-FET PET-BASED RESPONSE TO BEVACIZUMAB-BASED REGIMENS IN PATIENTS WITH GLIOBLASTOMA AT RELAPSE USING THE PET RANO 1.0 CRITERIA
European Association of Neuro-Oncology 2025, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.005]
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Abstract
IMG-61. Assessment of18F-FET PET-based response to bevacizumab-based regimens in patients with glioblastoma at relapse using the PET RANO 1.0 criteria
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, SNO / WFNOS 2025, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.1140]
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Journal Article
ML-EM based dual tracer PET image reconstruction with inclusion of prompt gamma attenuation
Physics in medicine and biology 70(1), 015009 - (2025) [10.1088/1361-6560/ad9660]
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Abstract
BIOM-82. GLIOBLASTOMA BEYOND THE ENHANCING TUMOR MARGINS: A LONGITUDINAL CASE STUDY COMPARING FET PET WITH MRI-BASED AI INFILTRATION MAPS
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, WFNOS/SNO 2025, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.0170]
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Poster (Other)
MINDset: A FAIR Infrastructure for Multimodal Neuroimaging Data
Tag der Forschungsdaten in NRW 2025, RWTH AachenRWTH Aachen, Germany, 18 Nov 2025 - 18 Nov 2025
[10.34734/FZJ-2025-04524]
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Journal Article
Neurometabolic Signatures of Gastrointestinal Symptoms in the Insula of Crohn's Disease Patients: Explorative Findings from a 7T MRS Study
Frontiers in human neuroscience 2025, 1620488 (2025) [10.3389/fnhum.2025.1620488]
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Journal Article - Online First
European NeuroOncology Quality Assessment (ENOQUA): A European Organization for the Research and Treatment of Cancer (EORTC) Brain Tumor Group Research Project
Neuro-oncology practice -, npaf103 (2025) [10.1093/nop/npaf103]
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Abstract
P10.12.A DIAGNOSIS OF TREATMENT-RELATED CHANGES IN CHILDREN AND ADOLESCENTS WITH BRAIN AND SPINAL TUMORS: A COST-EFFECTIVENESS ANALYSIS USING MRI AND [18F]-FET PET
European Association of Neuro-Oncology 2025, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.323]
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Journal Article
Diagnosis of treatment-related changes in children and adolescents with brain and spinal tumors: a cost-effectiveness analysis using MRI and [18 F]FET PET
European journal of nuclear medicine and molecular imaging 52(12), 4616-4626 (2025) [10.1007/s00259-025-07377-x]
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Contribution to a conference proceedings
High-Throughput CPU/GPU Monte Carlo Scatter Simulation for the Jülich BrainPET-7T Insert
2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD), YokohamaYokohama, Japan, 1 Nov 2025 - 8 Nov 2025
IEEE 1-1 (2025) [10.1109/NSS/MIC/RTSD57106.2025.11287984]
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Journal Article
Structural alterations as a predictor of depression – a 7-Tesla MRI-based multidimensional approach
Molecular psychiatry 30, 2517–2524 (2025) [10.1038/s41380-024-02854-5]
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Poster (After Call)
Hirnaktivierung der auditiv semantischen und syntaktischen Sprachverarbeitung bei Menschen mit Aphasie mittels (f)MRT
Tagung der Gesellschaft zur Aphasieforschung und –behandlung (GAB), AachenAachen, Germany, 2 Oct 2025 - 4 Oct 2025
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Journal Article
Development of an echo‐shifted, multi‐echo, gradient‐echo sequence for T 2 * quantification of slow‐relaxing water pools
Magnetic resonance in medicine 94(5), 2057-2070 (2025) [10.1002/mrm.30624]
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Contribution to a conference proceedings
Final Draft of PETSIRD v1.0: A Proposed Standard for PET Raw Data
2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD), YokohamaYokohama, Japan, 1 Nov 2025 - 8 Nov 2025
IEEE 1-1 (2025) [10.1109/NSS/MIC/RTSD57106.2025.11287540]
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Poster (Invited)
Design and Construction of a Geometrical and Head Phantom with Internal Carotid Inserts for Flow Simulation in Image-Derived Input Function with 3T and 7T MR-Brainpet Insert Studies.
American Association of Physicists in Medicine, AAPM 2025, WashingtonWashington, USA, 27 Jul 2025 - 30 Jul 2025
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Abstract
INNV-35. Artificial intelligence in Neuro-Oncology: Mapping the field
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, SNO / WFNOS 2025, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.0924]
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Journal Article
Value of artificial intelligence in neuro-oncology
The lancet / Digital health 7(9), 100876 - (2025) [10.1016/j.landig.2025.100876]
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Abstract
P03.25.B CLINICAL UTILITY OF [18F]FET PET IN PATIENTS WITH CIRCUMSCRIBED ASTROCYTIC GLIOMA
European Association of Neuro-Oncology, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.184]
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Abstract
IMG-88. Prognostic relevance of preoperative FET PET in patients with newly diagnosed glioblastoma
7th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies, HonoluluHonolulu, USA, 20 Nov 2025 - 23 Nov 2025
(2025) [10.1093/neuonc/noaf201.1167]
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Journal Article
Editorial for “Sodium MRI of the Lumbar Intervertebral Disks of the Human Spine: An Ex Vivo Study”
Journal of magnetic resonance imaging 61(3), 1513-1514 (2025) [10.1002/jmri.29530]
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Abstract
OS02.6.A MICCAI BRAIN TUMOR SEGMENTATION - METASTASES (BRATS-METS) 2025 LIGHTHOUSE CHALLENGE: COMPETITIVE ENVIRONMENT FOR THE DEVELOPMENT OF ROBUST AUTOMATIC SEGMENTATION ALGORITHMS FOR PRE- AND POST-TREATMENT BRAIN METASTASES
European Association of Neuro-Oncology 2025, EANO 2025, PraguePrague, Czech Republic, 16 Oct 2025 - 19 Oct 2025
(2025) [10.1093/neuonc/noaf193.036]
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