In the Team “High-Energy X-Ray Scattering and Imaging”, we conceptualize and develop a variety of complementary high energy X-ray scattering and imaging methods. We use these to investigate bulk properties and transport phenomena of catalyst materials and corresponding devices under reaction conditions on the atomic to mesoscale. For example, we develop novel methods to minimize background scattering, to enable quantitative measurements on an absolute scale, to investigate the electronic structure of atoms on a site-specific basis and to measure three-dimensional local structural properties of micro- to nanoscale samples. These methodological advances allow us to gain novel insights into a wide range of scientific questions.