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Synthetic Cell Factories

Head of Department

Gruppenfoto SyncellAugust 2021

Prof. Dr. Jan Marienhagen
Institute of Bio- and Geosciences
IBG-1: Biotechnology
Forschungszentrum Jülich GmbH
52425 Jülich
Germany








Cover ACS






We want to contribute to the understanding of bacterial metabolism and are interested in expanding the biosynthetic capabilities of microorganisms for applied purposes.

We focus on the engineering of Corynebacterium glutamicum for the sustainable production of value-added small molecules such as natural products, fine chemicals or pharmaceutical building blocks from biomass and other waste streams rich in carbon and energy.

In addition, we are developing new molecular tools for the editing of bacterial genomes and the high-throughput screening of metabolite producing bacteria at the single cell level using biosensors and fluorescence-activated cell sorting (FACS).



Former head of group

Dr. Lothar Eggeling


 

News and Highlights

January 2022Api´s cover design for an issue was selected by ACS Sustainable Chemistry and Engineering (https://pubs.acs.org/toc/ascecg/9/51)
December 2021Api´s paper on “Microbial Polyphenol Production in a Biphasic Process” accepted by ACS Sustainable Chemistry and Engineering (https://doi.org/10.1021/acssuschemeng.1c05865)
November 2021Joined manuscript with Julia Frunzke´s group on biosensor-based isolation of amino acid-producing Vibrio natriegens strains published (https://doi.org/10.1016/j.mec.2021.e00187)
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