Positron emission tomography (PET) is a unique modality for imaging normal and diseased metabolical functions in vivo, in a quantitative manner.

To allow for optimum image quality, it is necessary to continuously improve the physical, technological and methodological prerequisites of simultaneous recording. For this purpose, we work to develop innovative reconstruction programs and procedures to correct for the different influences on the quantitative accuracy of PET. Furthermore, methods to extract and analyse diagnostically relevant parameters are studied.

Although PET is the most sensitive tool for metabolic in vivo imaging, magnetic resonance imaging (MRI) delivers unsurpassed anatomical images and additional functional information, which is complementary to that obtained from PET. The hybrid 3T MR-PET and 9.4T MR-PET scanners installed in our institute open new frontiers by utilising both imaging modalities simultaneously. This advance in technology means that new physical and methodological challenges must be addressed. Important issues relate to the assessment of the new PET detector technology, corrections for attenuation, scatter and motion correction, as well as PET reconstruction guided by MRI.

The hybrid scanners enable the simultaneous highlighting of activated brain networks via fMRI and a representation of the biochemistry using PET. Furthermore, the hybrid MR-PET scanner is also able to serve as a platform to validate MR-based measurements of biochemical and physiological functions with the help of PET.

Research Topics

  • Technical Aspects of Positron-Emmision-Tomography
  • Technical Aspects of MR-PET


Dr. Christoph Lerche


Building 15.9 / Room 2001e

+49 2461/61-96524


Research Group

Heba AlrakhPhD StudentBuilding 15.2v / Room 309+49 2461/61-96687
Dr.rer.medic. Claudia Régio BrambillaPostdoctoral researcherBuilding 15.2v / Room 308+49 2461/61-5738
Silke FrenschNoneBuilding 15.2 / Room 246+49 2461/61-6058
Ahlam IssaNoneBuilding 15.2 / Room r312+49 2461/61-96858
Yannic KittenNoneBuilding 15.2v / Room 309+49 2461/61-96687
Dr. Chong LiNoneBuilding 15.2v / Room 309+49 2461/61-96687
Debora NiekaemperNoneBuilding 15.2 / Room 312+49 2461/61-6343
Dr. Jürgen ScheinsNoneBuilding 15.9 / Room 2011+49 2461/61-2740
Dipl.-Ing. Lutz TellmannNoneBuilding 15.2 / Room 245+49 2461/61-5243

Last Modified: 16.02.2023