The working group Radiotracer Development, led by Prof. Dr. Johannes Ermert, focuses on the radiosynthesis of novel positron emission tomography (PET) probes for studies on brain function and the diagnosis of neurodegenerative diseases. A key objective is to develop efficient synthesis protocols that allow for rapid and automated production of the desired radiotracers. The radiotracers undergo extensive preclinical evaluation, with promising candidates progressing to clinical applications.

The research primarily focuses on two main areas: the synthesis of new ¹⁸F-labeled amino acids for the diagnosis of brain tumors and neurodegenerative diseases, and the development of ¹¹C- and ¹⁸F-labeled ligands for various receptor systems in the brain. To achieve these objectives, the working group develops innovative radiolabeling strategies that enable the synthesis of these compounds.

Another important research area involves optimizing radiopharmaceutical synthesis methods to improve automation and product quality, ensuring efficient and reproducible production for clinical use.